Primary Site >> Colorectal Cancer

Gene >> ITGB2

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Ref: Antibody-mediated killing of human tumor cells by attached effector cells.
PMID: 3335025
Ref: Endothelial leukocyte adhesion molecule 1: direct expression cloning and functional interactions.
PMID: 1689848
Ref: Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro.
PMID: 1362041
Ref: Interleukin-2-activated killer cell activity in colorectal tumor patients: evaluation of in vitro effects by prothymosin alpha1.
PMID: 9292704
Ref: Preclinical studies with prothymosin alpha1 on mononuclear cells from tumor patients.
PMID: 9637344
Ref: [Overexpression of B7-1 amd B7-2 by LFA-1 positive lymphocytes in chronic inflammatory bowel diseases].
PMID: 14518246
Ref: Involvement of LFA-1 in hepatic NK cell (pit cell)-mediated cytolysis and apoptosis of colon carcinoma cells.
PMID: 10424290
Ref: Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer.
PMID: 10433007
Ref: Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients.
PMID: 10458690
Ref: Initial exposed phosphatidylserine levels correlate with cellular response to cytotoxic drugs.
PMID: 12581191
Ref: Correlation between invasiveness of colorectal tumor cells and adhesive potential under flow.
PMID: 14981941
Ref: Neutrophils migrate across intestinal epithelium using beta2 integrin (CD11b/CD18)-independent mechanisms.
PMID: 15086389
Ref: Fluorouracil induces apoptosis and surface molecule modulation of peripheral blood leukocytes.
PMID: 15485462
Ref: Analysis of gene expression profiles reveals novel correlations with the clinical course of colorectal cancer.
PMID: 18306933
Ref: Human eosinophils exert TNF-alpha and granzyme A-mediated tumoricidal activity toward colon carcinoma cells.
PMID: 21068403
Ref: Predicting ulcerative colitis-associated colorectal cancer using reverse-transcription polymerase chain reaction analysis.
PMID: 21859567
Ref: Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma.
PMID: 22783056
Ref: Innate immunity gene polymorphisms and the risk of colorectal neoplasia.
PMID: 23803696
Ref: Quantitative proteomic analysis of paired colorectal cancer and non-tumorigenic tissues reveals signature proteins and perturbed pathways involved in CRC progression and metastasis.
PMID: 26054784
Ref: Decreased expression of the beta2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice.
PMID: 29207960