Primary Site >> Colorectal Cancer
Gene >> ITGB1
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Ref: Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration. PMID: 2369727 |
Ref: Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1. PMID: 1716464 Ref: Role of beta 1 integrins in tumor cell adhesion to cultured human endothelial cells. PMID: 1753702 |
Ref: Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. PMID: 1384639 |
Ref: Altered glycosylation of integrin adhesion molecules in colorectal cancer cells and decreased adhesion to the extracellular matrix. PMID: 8314518 Ref: Models of colorectal tumour differentiation. PMID: 8348537 Ref: Loss of cell-cell and cell-matrix adhesion molecules in colorectal cancer. PMID: 8353041 Ref: Expression of 67 kDa laminin receptor in human breast cancer cells: regulation by progestins. PMID: 8472397 |
Ref: A novel mechanism of colon carcinoma cell adhesion to the endothelium triggered by beta 1 integrin chain. PMID: 7509799 Ref: Expression of beta 1 integrin in laminin-adhesion-selected human colon cancer cell lines of varying tumorigenicity. PMID: 7544773 Ref: How intestinal epithelial cell differentiation inhibits the cell-entry of Yersinia pseudotuberculosis in colon carcinoma Caco-2 cell line in culture. PMID: 7867897 Ref: Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines. PMID: 7954430 Ref: Phenotypical and functional characteristics of tumor-infiltrating lymphocytes from colon carcinomas stimulated with rIL-2 and rIL-4 in vitro: comparison with lymphocytes of the normal colon mucosa and the peripheral blood. PMID: 8074499 |
Ref: A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma. PMID: 7495750 Ref: Effect of TGF-beta on differentiated organoids of the colon carcinoma cell line LIM 1863. PMID: 7590899 Ref: Morphological and functional characteristics of tumor-infiltrating lymphocytes from human colorectal cancers after stimulation with rIL-2. PMID: 7649213 Ref: CEA-mediated homotypic aggregation of human colorectal carcinoma cells in a malignant effusion. PMID: 7850776 |
Ref: Colon-cancer cell variants producing regressive tumors in syngeneic rats, unlike variants yielding progressive tumors, attach to interstitial collagens through integrin alpha2beta1. PMID: 8631595 Ref: Mechanisms of colon cancer binding to substratum and cells. PMID: 8769278 Ref: Induction of fibroblast gelatinase B expression by direct contact with cell lines derived from primary tumor but not from metastases. PMID: 8968108 |
Ref: Role of integrins and evidence for two distinct mechanisms mediating human colorectal carcinoma cell interaction with peritoneal mesothelial cells and extracellular matrix. PMID: 9177905 Ref: Oncogenic Ki-ras but not oncogenic Ha-ras blocks integrin beta1-chain maturation in colon epithelial cells. PMID: 9388239 |
Ref: Expression of 32/67-kDa laminin receptor in laminin adhesion-selected human colon cancer cell lines. PMID: 9459140 Ref: Enhancement of metastatic activity of colon cancer as influenced by expression of cell surface antigens. PMID: 9733622 |
Ref: Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes. PMID: 10022502 Ref: Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer. PMID: 10433007 Ref: Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients. PMID: 10458690 Ref: Beta1-integrin-mediated dynamic adhesion of colon carcinoma cells to extracellular matrix under laminar flow. PMID: 10651304 |
Ref: Effects of increased ambient pressure on colon cancer cell adhesion. PMID: 10797565 Ref: Establishment of a human colon cancer cell line (PMF-ko14) displaying highly metastatic activity. PMID: 10853016 |
Ref: Colon cancer cell adhesion to endothelial E-selectin inhibits detachment of endothelial cells through activation of beta(1)-integrin. PMID: 11485302 |
Ref: Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. PMID: 12134161 Ref: Ionizing radiation modulates cell surface integrin expression and adhesion of COLO-320 cells to collagen and fibronectin in vitro. PMID: 12491059 |
Ref: Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism. PMID: 12517943 Ref: Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-beta1 integrin complex in colon cancer cells. PMID: 12865932 Ref: ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. PMID: 12892714 |
Ref: Hypertonic saline impedes tumor cell-endothelial cell interaction by reducing adhesion molecule and laminin expression. PMID: 15232542 Ref: Inhibition of alpha5 integrin decreases PI3K activation and cell adhesion of human colon cancers. PMID: 15300173 Ref: Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. PMID: 15466189 |
Ref: Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy. PMID: 15644133 Ref: Selective inhibition of cyclooxygenase-2 inhibits colon cancer cell adhesion to extracellular matrix by decreased expression of beta1 integrin. PMID: 15723653 Ref: Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells. PMID: 15769846 Ref: Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility. PMID: 15930282 |
Ref: FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. PMID: 17317726 Ref: The relationship between GDNF and integrins in human colorectal cancer cell activity. PMID: 17708263 Ref: Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction. PMID: 17898132 Ref: The impact of conventional and heavy ion irradiation on tumor cell migration in vitro. PMID: 18058372 |
Ref: Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer. PMID: 18245490 Ref: Alpha2beta1 integrin regulates lineage commitment in multipotent human colorectal cancer cells. PMID: 18664572 Ref: Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis. PMID: 18676377 Ref: Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. PMID: 18765800 |
Ref: Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas. PMID: 19714342 Ref: Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. PMID: 20332776 Ref: Colon cancer stem cells: promise of targeted therapy. PMID: 20420952 Ref: Molecular identification and targeting of colorectal cancer stem cells. PMID: 21311095 |
Ref: Proteome of human colon cancer stem cells: a comparative analysis. PMID: 21455326 Ref: Gene expression profile can predict pathological response to preoperative chemoradiotherapy in rectal cancer. PMID: 21471518 Ref: Common cancer stem cell gene variants predict colon cancer recurrence. PMID: 21918173 |
Ref: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers. PMID: 22670157 Ref: [Differential analysis of lymphocyte subsets between colorectal carcinoma patients and healthy individuals]. PMID: 22768866 Ref: Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer : future possibilities for personalised treatment by use of biomarkers. PMID: 22825001 |
Ref: [Changes of lymphocyte subsets before and after chemotherapy in colorectal carcinoma patients]. PMID: 23643003 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 |
Ref: Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma. PMID: 24173294 Ref: Prognostic value of beta1 integrin expression in colorectal liver metastases. PMID: 24427350 Ref: SNPs in microRNA-binding sites in the ITGB1 and ITGB3 3'-UTR increase colorectal cancer risk. PMID: 24777809 Ref: beta1 integrin modulates tumor growth and apoptosis of human colorectal cancer. PMID: 24807392 Ref: Stem cells, colorectal cancer and cancer stem cell markers correlations. PMID: 25729599 |
Ref: beta1 integrin mediates colorectal cancer cell proliferation and migration through regulation of the Hedgehog pathway. PMID: 25387809 Ref: Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer. PMID: 25487679 Ref: Functional polymorphisms of ITGB1 are associated with clinical outcome of Chinese patients with resected colorectal cancer. PMID: 25894721 Ref: CD4+CD29+T cells are blamed for the persistent inflammatory response in ulcerative colitis. PMID: 26045768 Ref: Expression of ITGB1 predicts prognosis in colorectal cancer: a large prospective study based on tissue microarray. PMID: 26722470 |
Ref: KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway. PMID: 26847701 Ref: Effect of colorectal cancer on the number of normal stem cells circulating in peripheral blood. PMID: 27779706 |
Ref: Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer. PMID: 27593447 Ref: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer. PMID: 28237538 Ref: P53-induced miR-30e-5p inhibits colorectal cancer invasion and metastasis by targeting ITGA6 and ITGB1. PMID: 28656629 |
Ref: Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells. PMID: 29515254 Ref: Prognostic value of increased integrin-beta 1 expression in solid cancers: a meta-analysis. PMID: 29636624 Ref: Laminin alpha1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma. PMID: 29907957 Ref: Cancer stem cells as targets for DC-based immunotherapy of colorectal cancer. PMID: 30104575 |