Primary Site >> Colorectal Cancer

Gene >> ITGAV

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Ref: A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6.
PMID: 7513610
Ref: Von Willebrand's factor mediates the adherence of human tumoral cells to human endothelial cells and ticlopidine interferes with this effect.
PMID: 11100896
Ref: Activated T lymphocytes bind in situ to stromal tissue of colon carcinoma but lack adhesion to tumor cells.
PMID: 11169447
Ref: Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells.
PMID: 15260832
Ref: Netrin-1 specifically enhances cell spreading on fibronectin in human glioblastoma cells.
PMID: 19967060
Ref: Relationship between the expression of the extracellular matrix genes SPARC, SPP1, FN1, ITGA5 and ITGAV and clinicopathological parameters of tumor progression and colorectal cancer dissemination.
PMID: 23128103
Ref: Expression of integrin genes and proteins in progression and dissemination of colorectal adenocarcinoma.
PMID: 23705994
Ref: Overexpression of the ITGAV gene is associated with progression and spread of colorectal cancer.
PMID: 25275062
Ref: Genetic and Immunohistochemical Expression of Integrins ITGAV, ITGA6, and ITGA3 As Prognostic Factor for Colorectal Cancer: Models for Global and Disease-Free Survival.
PMID: 26674523
Ref: CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells.
PMID: 27593923
Ref: miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells.
PMID: 28905214
Ref: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
PMID: 29068474
Ref: Genetic variants in the VEGF pathway as prognostic factors in stages II and III colon cancer.
PMID: 29282362
Ref: Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells.
PMID: 29515254