Primary Site >> Colorectal Cancer
Gene >> ITGAM
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Ref: Effect of anti-CD3 antibody on the generation of interleukin-2-activated lymphocytes from tumor tissues of gastrointestinal cancer. PMID: 1386555 |
Ref: Study of effect of surgical stress on immunity in patients with gastrointestinal cancer. PMID: 8274052 |
Ref: DCC protein expression in hematopoietic cell populations and its relation to leukemogenesis. PMID: 8609244 Ref: Mechanisms of tumor-induced immunosuppression: evidence for contact-dependent T cell suppression by monocytes. PMID: 8972484 |
Ref: Prothymosin alpha 1 effects in vitro on chemotaxis, cytotoxicity and oxidative response of neutrophils from melanoma, colorectal and breast tumor patients. PMID: 9568546 |
Ref: Acquired immunity in nude mice induced by expression of the IL-2 or IL-4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus. PMID: 10404069 |
Ref: Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells. PMID: 10679114 |
Ref: Hydrodynamic shear regulates the kinetics and receptor specificity of polymorphonuclear leukocyte-colon carcinoma cell adhesive interactions. PMID: 11698478 |
Ref: Fluid shear- and time-dependent modulation of molecular interactions between PMNs and colon carcinomas. PMID: 12225977 |
Ref: [Expression of leucocyte cell-surface antigens on colon cancer cell line HR8348]. PMID: 15067730 Ref: Neutrophils migrate across intestinal epithelium using beta2 integrin (CD11b/CD18)-independent mechanisms. PMID: 15086389 Ref: Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis. PMID: 15456639 Ref: Fluorouracil induces apoptosis and surface molecule modulation of peripheral blood leukocytes. PMID: 15485462 |
Ref: Effect of bone marrow-derived monocytes transfected with RNA of mouse colon carcinoma on specific antitumor immunity. PMID: 15655840 Ref: [Evaluation of the minimal invasiveness of laparoscopic operation for colorectal carcinoma]. PMID: 16224652 |
Ref: Multiplex detection of surface molecules on colorectal cancers. PMID: 16485257 Ref: In vivo tumor targeting using a novel intestinal pathogen-based delivery approach. PMID: 16849571 |
Ref: Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. PMID: 17178380 |
Ref: PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor. PMID: 17637826 Ref: CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer. PMID: 18830416 |
Ref: Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer. PMID: 19494278 Ref: Neutrophil influx and chemokine production during the early phases of the antitumor response to the vascular disrupting agent DMXAA (ASA404). PMID: 19649209 Ref: Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer. PMID: 19816950 |
Ref: Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo. PMID: 19669608 Ref: Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor. PMID: 20042467 Ref: Organ microenvironment plays significant roles through Fas ligand in vaccine-induced CD4(+) T cell dependent suppression of tumor growth at the orthotopic site. PMID: 20637014 |
Ref: Tumor infiltration by FcgammaRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma. PMID: 20715106 Ref: S100A8/A9 activate key genes and pathways in colon tumor progression. PMID: 21228116 Ref: Intratumoral injection of interleukin-2 augments the local and abscopal effects of radiotherapy in murine rectal cancer. PMID: 21443690 Ref: Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PMID: 21559338 Ref: Prognostic role of CD10(+) myeloid cells in association with tumor budding at the invasion front of colorectal cancer. PMID: 21599811 Ref: High-resolution imaging and antitumor effects of GFP(+) bone marrow-derived cells homing to syngeneic mouse colon tumors. PMID: 21975022 |
Ref: Myeloid cells positive for CD10 at invasion front can predict poor outcome in stage II colorectal cancer. PMID: 21773689 Ref: Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice. PMID: 22461519 Ref: Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma. PMID: 22783056 Ref: CXCL17 expression by tumor cells recruits CD11b+Gr1 high F4/80- cells and promotes tumor progression. PMID: 22952881 Ref: [Myeloid-derived suppressor cells in cancer patients]. PMID: 23267890 |
Ref: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer. PMID: 22469976 Ref: Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo. PMID: 22926062 Ref: Enhanced antitumoral activity of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models. PMID: 22949155 Ref: Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis. PMID: 23081697 Ref: Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells. PMID: 23184679 Ref: Circulating immunosuppressive cells of prostate cancer patients before and after radical prostatectomy: profile comparison. PMID: 23421558 Ref: Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma. PMID: 23437326 Ref: Bone marrow-derived CD11b+Jagged2+ cells promote epithelial-to-mesenchymal transition and metastasization in colorectal cancer. PMID: 23722542 Ref: Role of NK cell subsets in organ-specific murine melanoma metastasis. PMID: 23776508 Ref: Reduced type II interleukin-4 receptor signalling drives initiation, but not progression, of colorectal carcinogenesis: evidence from transgenic mouse models and human case-control epidemiological observations. PMID: 23784081 Ref: [Study on inhibitory effect of combined administration of bear bile powder and cyclophosphamide on colorectal cancer liver metastasis by regulating tumor microenvironment]. PMID: 23847953 Ref: MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. PMID: 23867499 Ref: Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1+ myeloid cells and facilitate liver metastasis. PMID: 23891973 Ref: Fms-like tyrosine kinase 3 receptor ligand (Flt3L)-based vaccination administered with an adenoviral vector prevents tumor growth of colorectal cancer in a BALB/c mouse model. PMID: 24114287 |
Ref: IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice. PMID: 24492468 Ref: A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model. PMID: 25051201 Ref: Immune consequences of decreasing tumor vasculature with antiangiogenic tyrosine kinase inhibitors in combination with therapeutic vaccines. PMID: 25092771 Ref: Extraintestinal helminth infection reduces the development of colitis-associated tumorigenesis. PMID: 25210492 Ref: Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer. PMID: 25294811 |
Ref: Preparation and Evaluation of 99mTc-labeled anti-CD11b Antibody Targeting Inflammatory Microenvironment for Colon Cancer Imaging. PMID: 25346241 Ref: Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment. PMID: 25351848 Ref: Intermittent chemotherapy can retain the therapeutic potential of anti-CD137 antibody during the late tumor-bearing state. PMID: 25363339 Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. PMID: 25445327 Ref: Pre- and post-operative evaluation: percentages of circulating myeloid-derived suppressor cells in rectal cancer patients. PMID: 25591589 Ref: Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer. PMID: 25638150 Ref: Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients. PMID: 25823653 Ref: Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer. PMID: 25869209 Ref: Activation of mucosal mast cells promotes inflammation-related colon cancer development through recruiting and modulating inflammatory CD11b(+)Gr1(+) cells. PMID: 25986744 Ref: Tumor-infiltrating lymphocytes, forkhead box P3, programmed death ligand-1, and cytotoxic T lymphocyte-associated antigen-4 expressions before and after neoadjuvant chemoradiation in rectal cancer. PMID: 26209749 Ref: TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases. PMID: 26483205 Ref: Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment. PMID: 26673090 Ref: IL-11 induces differentiation of myeloid-derived suppressor cells through activation of STAT3 signalling pathway. PMID: 28781374 |
Ref: Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis. PMID: 26341919 Ref: IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4(+) T cells. PMID: 26759006 Ref: Leukocyte populations and IL-6 in the tumor microenvironment of an orthotopic colorectal cancer model. PMID: 26893144 Ref: IL-15 superagonist/IL-15RalphaSushi-Fc fusion complex (IL-15SA/IL-15RalphaSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas. PMID: 26910920 Ref: Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma. PMID: 27045955 Ref: Vam3, a Compound Derived from Vitis amurensis Rupr., Attenuated Colitis-Related Tumorigenesis by Inhibiting NF-kappaB Signaling Pathway. PMID: 27679575 Ref: Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients. PMID: 28008330 Ref: The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells. PMID: 28123883 Ref: A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity. PMID: 29263903 |
Ref: IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis. PMID: 27120577 Ref: Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site. PMID: 28243692 Ref: Antitumor activity of orally administered maitake alpha-glucan by stimulating antitumor immune response in murine tumor. PMID: 28278221 Ref: Homeobox B9 Mediates Resistance to Anti-VEGF Therapy in Colorectal Cancer Patients. PMID: 28298545 Ref: Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors. PMID: 28337197 Ref: Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. PMID: 28385737 Ref: Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3(+) regulatory T cells in murine colon cancer. PMID: 28405523 Ref: [Circulating Myeloid Suppressor Cells and Their Role in Tumour Immunology]. PMID: 28471197 Ref: CD169 Expressing Macrophage, a Key Subset in Mesenteric Lymph Nodes Promotes Mucosal Inflammation in Dextran Sulfate Sodium-Induced Colitis. PMID: 28694804 Ref: Interleukin-6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapy. PMID: 28749573 Ref: Prolonged Deleterious Influences of Chemotherapeutic Agent CPT-11 on Resident Peritoneal Macrophages and B1 Cells. PMID: 29354128 |
Ref: Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis. PMID: 29636751 Ref: Intraperitoneal oxaliplatin administration inhibits the tumor immunosuppressive microenvironment in an abdominal implantation model of colon cancer. PMID: 29956798 Ref: Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment. PMID: 30021725 Ref: Surgical trauma contributes to progression of colon cancer by downregulating CXCL4 and recruiting MDSCs. PMID: 30055136 Ref: Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis. PMID: 30202097 |