Primary Site >> Liver Cancer

Gene >> IQGAP2

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Ref: Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.
PMID: 18180285
Ref: Quantitative proteomic signature of liver cancer cells: tissue transglutaminase 2 could be a novel protein candidate of human hepatocellular carcinoma.
PMID: 18646787
Ref: IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.
PMID: 20977743
Ref: Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
PMID: 21104785
Ref: Subcellular tissue proteomics of hepatocellular carcinoma for molecular signature discovery.
PMID: 21913717
Ref: IQGAP2, A candidate tumour suppressor of prostate tumorigenesis.
PMID: 22406297
Ref: Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma.
PMID: 22973521
Ref: Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma.
PMID: 23951254
Ref: Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.
PMID: 24998570
Ref: Role of the tumor suppressor IQGAP2 in metabolic homeostasis: Possible link between diabetes and cancer.
PMID: 25254002
Ref: Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression.
PMID: 26464624
Ref: IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-kappaB pathway.
PMID: 27401546
Ref: IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.
PMID: 27488117