Primary Site >> Pancreatic Cancer

Gene >> IQGAP1

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Ref: Expression of MTA1 promotes motility and invasiveness of PANC-1 pancreatic carcinoma cells.
PMID: 14735193
Ref: Rac1 activation inhibits E-cadherin-mediated adherens junctions via binding to IQGAP1 in pancreatic carcinoma cells.
PMID: 19737400
Ref: A molecular rheostat at the interface of cancer and diabetes.
PMID: 23639840
Ref: Overexpression of IQGAP1 in human pancreatic cancer.
PMID: 24103286
Ref: IQGAP1 selectively interacts with K-Ras but not with H-Ras and modulates K-Ras function.
PMID: 24462863
Ref: Potential involvement of IQGAP1 in proliferation and metastasis of human pancreatic cancer.
PMID: 27100492
Ref: Fructose-1,6-bisphosphatase Inhibits ERK Activation and Bypasses Gemcitabine Resistance in Pancreatic Cancer by Blocking IQGAP1-MAPK Interaction.
PMID: 28720574
Ref: Interleukin-6 promotes pancreatic cancer cell migration by rapidly activating the small GTPase CDC42.
PMID: 29853638