Primary Site >> Liver Cancer

Gene >> IQGAP1

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Ref: Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.
PMID: 18180285
Ref: miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma.
PMID: 19843643
Ref: IQGAP1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation by Akt activation.
PMID: 20530982
Ref: IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.
PMID: 20977743
Ref: Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
PMID: 21104785
Ref: Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma.
PMID: 22973521
Ref: Bile acids activate YAP to promote liver carcinogenesis.
PMID: 24268772
Ref: Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.
PMID: 24998570
Ref: Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression.
PMID: 26464624
Ref: IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.
PMID: 27488117
Ref: Hepatitis B Virus X Protein Stimulates Proliferation, Wound Closure and Inhibits Apoptosis of HuH-7 Cells via CDC42.
PMID: 28282856