Primary Site >> Stomach Cancer
Gene >> IQGAP1
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Ref: Decreased binding sites of angiotensin II in rat LY-80 and AH109A tumour and human gastric cancer using quantitative in vitro autoradiography. PMID: 10853686 |
Ref: Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e-cadherin in gastric cancers. PMID: 11275980 Ref: IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A. PMID: 11289714 |
Ref: MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain. PMID: 12739007 |
Ref: Nucleotide variants within the IQGAP1 gene in diffuse-type gastric cancers. PMID: 15611933 Ref: Helicobacter felis eradication restores normal architecture and inhibits gastric cancer progression in C57BL/6 mice. PMID: 15940628 |
Ref: IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells. PMID: 17957782 Ref: Combined analysis of Rac1, IQGAP1, Tiam1 and E-cadherin expression in gastric cancer. PMID: 18246045 |
Ref: Genetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancer. PMID: 21318219 Ref: RhoC protein stimulates migration of gastric cancer cells through interaction with scaffold protein IQGAP1. PMID: 21537845 |
Ref: RhoC regulates the proliferation of gastric cancer cells through interaction with IQGAP1. PMID: 23145020 |
Ref: Helicobacter pylori-induced alteration of epithelial cell signaling and polarity: a possible mechanism of gastric carcinoma etiology and disparity. PMID: 23629919 |
Ref: An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2. PMID: 25398317 |
Ref: Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer. PMID: 26919099 |
Ref: Asparaginyl endopeptidase improves the resistance of microtubule-targeting drugs in gastric cancer through IQGAP1 modulating the EGFR/JNK/ERK signaling pathway. PMID: 28223821 Ref: Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers. PMID: 29073199 |