Primary Site >> Colorectal Cancer
Gene >> IL4
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Ref: Cytokine effects and role of adhesive proteins and Fc receptors in human macrophage-mediated antibody dependent cellular cytotoxicity. PMID: 1675219 Ref: Adjuvant adoptive immunotherapy with IL2 and lymphocytes from tumor-bearing mice: in vitro tumor-stimulated lymphocytes are more effective than LAK cells. PMID: 1787836 Ref: Effects of cytokines on in vitro growth of tumor-infiltrating lymphocytes obtained from human primary and metastatic liver tumors. PMID: 1847844 Ref: Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state. PMID: 1913671 Ref: Interleukin-4 augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity. PMID: 2021957 |
Ref: Inhibition of colon and breast carcinoma cell growth by interleukin-4. PMID: 1728401 |
Ref: Expansion of tumor-infiltrating lymphocytes from human tumors using the T-cell growth factors interleukin-2 and interleukin-4. PMID: 8280717 Ref: A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin. PMID: 8314773 Ref: Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression. PMID: 8344757 |
Ref: Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. PMID: 7874864 Ref: Inhibition of IFN-gamma activity in supernatants from stimulated human intestinal mononuclear cells prevents up-regulation of the polymeric Ig receptor in an intestinal epithelial cell line. PMID: 8021503 |
Ref: The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells. PMID: 7600527 Ref: Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV). PMID: 7657667 Ref: Expansion of mucin-reactive T-helper lymphocytes from patients with colorectal cancer. PMID: 7663570 Ref: Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. PMID: 7674335 Ref: Recombinant human interleukin 4 has antiproliferative activity on human tumor cell lines derived from epithelial and nonepithelial histologies. PMID: 7743520 Ref: Superantigen-induced human CD4+ helper/killer T cell phenomenon. Selective induction of Th1 helper/killer T cells and application to tumor immunotherapy. PMID: 7836762 Ref: Interleukin 4 down-regulates expression of c-kit and autocrine stem cell factor in human colorectal carcinoma cells. PMID: 8519688 Ref: Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells. PMID: 8530527 Ref: Macrophage colony-stimulating factor enhancement of antibody-dependent cellular cytotoxicity against human colon carcinoma cells. PMID: 8537095 |
Ref: Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma. PMID: 8566049 Ref: IL-4 and TNF-alpha induce changes in integrin expression and adhesive properties and decrease the lung-colonizing potential of HT-29 colon carcinoma cells. PMID: 8605730 Ref: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. PMID: 8609418 Ref: Antitumor effect induced by the expression of granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells. PMID: 8620478 Ref: Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733. PMID: 8621241 Ref: Disregulation in TH1 and TH2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. PMID: 8625361 Ref: Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1. PMID: 8645156 Ref: Differential effect of interleukin-4 and transforming growth factor beta 1 on expression of proto-oncogenes and autocrine insulin-like growth factor II in colorectal carcinoma cells. PMID: 8645306 Ref: Mechanisms of colon cancer binding to substratum and cells. PMID: 8769278 Ref: Expression of interleukin-4 in colon 26 cells induces both eosinophil mediated local tumor killing and T-cell mediated systemic immunity in vivo. PMID: 8810556 Ref: The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-alpha and interleukin-4 predicts improved survival. PMID: 8826937 Ref: Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas. PMID: 8891890 Ref: Phenotypical and functional differences of tumor-infiltrating lymphocytes from human colorectal cancers induced by costimulation with rIL-2 and rIL-4 in vitro. PMID: 9042222 Ref: Prognostic significance of immunological evaluation in colorectal cancer. PMID: 10851496 Ref: Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer. PMID: 10851498 Ref: Immunological directives for biotherapy improvement in the treatment of colorectal cancer. PMID: 10851527 |
Ref: Antitumor effect of murine colon carcinoma cells retrovirally transduced with interleukin-4 and granulocyte macrophage-colony stimulating factor genes. PMID: 8978596 Ref: Inhibition of growth and enhancement of differentiation of colorectal carcinoma cell lines by MAb MR6 and IL-4. PMID: 9178815 Ref: alphaV Integrins on HT-29 colon carcinoma cells: adhesion to fibronectin is mediated solely by small amounts of alphaVbeta6, and alphaVbeta5 is codistributed with actin fibers. PMID: 9223381 Ref: Modulation of interleukin (IL)-13 binding and signaling by the gammac chain of the IL-2 receptor. PMID: 9242704 Ref: Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. PMID: 9259401 Ref: Genetic modification of a carcinoma with the IL-4 gene increases the influx of dendritic cells relative to other cytokines. PMID: 9341783 Ref: Regulation of 15-lipoxygenase expression by cytokines. PMID: 9547609 Ref: The sCEA molecule suppressive role in NK and TH1 cell functions in colorectal cancer. PMID: 10851473 Ref: IL-10 and sIL-2R serum levels as possible peripheral blood prognostic markers in the passage from adenoma to colorectal cancer. PMID: 10851474 Ref: The role of the soluble CD30 serum level in colorectal cancer: a possible marker for a patient subset which could benefit from IL-2 biotherapy. PMID: 10851480 Ref: Immunological implications of alterations in the c-Ki-ras and p53 genes in the stepwise progression of colorectal cancer: indications for the improvement of prognosis, biotherapy treatment and tumor biology understanding PMID: 10851492 |
Ref: The significance of an increase in soluble interleukin-2 receptor level in colorectal cancer and its biological regulating role in the physiological switching of the immune response cytokine network from TH1 to TH2 and back. PMID: 9439647 Ref: Molecular mimicry of carcinoembryonic antigen by peptides derived from the structure of an anti-idiotype antibody. PMID: 9515808 Ref: Induction of T cell dependent acquired immunity in syngeneic mice by the combined expression of interleukin-4 and granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells. PMID: 9673355 Ref: Anti-metastatic and immunomodulating properties of the water extract from Celosia argentea seeds. PMID: 9853404 Ref: IgG2a induced by interleukin (IL) 12-producing tumor cell vaccines but not IgG1 induced by IL-4 vaccine is associated with the eradication of experimental metastases. PMID: 9865740 Ref: Disease stage prognostic indices in the early clinical screening of colorectal cancer patients. PMID: 10850345 |
Ref: Local expression of cytokines in human colorectal carcinoma: evidence of specific interleukin-6 gene expression. PMID: 9924696 Ref: T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice. PMID: 10049944 Ref: Enhancement of antibody dependent cellular cytotoxicity (ADCC) by combination of cytokines. PMID: 10211790 Ref: Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver. PMID: 10228796 Ref: Acquired immunity in nude mice induced by expression of the IL-2 or IL-4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus. PMID: 10404069 Ref: Immunohistochemical analysis of inflammation in primary sclerosing cholangitis. PMID: 10445798 Ref: Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes. PMID: 10449520 Ref: Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. PMID: 10499513 Ref: Suppression of the reactive oxygen intermediates production of human macrophages by colorectal adenocarcinoma cell lines. PMID: 10594687 |
Ref: Diversion of intestinal flow decreases the numbers of interleukin 4 secreting and interferon gamma secreting T lymphocytes in small bowel mucosa. PMID: 10601053 Ref: IL-10 enhances IL-2-induced proliferation and cytotoxicity by human intestinal lymphocytes. PMID: 10691913 Ref: Interleukin-4 mediates cell growth inhibition through activation of Stat1. PMID: 10744706 Ref: Combinations of the cytokines IL-12, IL-2 and IFN-alpha significantly augment whereas the cytokine IL-4 suppresses the cytokine-induced antibody-dependent cellular cytotoxicity of monoclonal antibodies 17-1A and BR55-2. PMID: 10843759 Ref: Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo. PMID: 11086063 |
Ref: Crucial role of cytokines in sex steroid formation in normal and tumoral tissues. PMID: 11165008 Ref: Influence of cytokines, monoclonal antibodies and chemotherapeutic drugs on epithelial cell adhesion molecule (EpCAM) and LewisY antigen expression. PMID: 11167991 Ref: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. PMID: 11169257 Ref: Endogenous production of IL-8 by human colorectal cancer cells and its regulation by cytokines. PMID: 11179473 Ref: Antitumor activity of expanded human tumor-infiltrating gammadelta T lymphocytes. PMID: 11490159 Ref: Ex vivo host response to gastrointestinal cancer cells presented by autologous dendritic cells. PMID: 11516202 Ref: [The levels of selected cytokines in patients with colorectal cancer--a preliminary report]. PMID: 11770312 Ref: Minimal costimulatory requirements for T cell priming and TH1 differentiation: activation of naive human T lymphocytes by tumor cells armed with bifunctional antibody constructs. PMID: 12747771 |
Ref: Decreased production of interleukin-12 and type 2 immune responses are marked in cachectic patients with colorectal and gastric cancer. PMID: 11907352 Ref: Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer. PMID: 11915173 Ref: Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine. PMID: 12006514 Ref: Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate. PMID: 12503617 |
Ref: Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer. PMID: 12637942 Ref: Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. PMID: 12702049 Ref: Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity. PMID: 12782590 Ref: Intensification of antitumor effect by T helper 1-dominant adoptive immunogene therapy for advanced orthotopic colon cancer. PMID: 12796406 Ref: Prevention of brain metastasis formation by local expression of interleukin-4 or hemagglutinin antigen. PMID: 12838474 Ref: mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-alpha through a mitogen-activated protein kinase pathway in human colon cancer cells. PMID: 12848848 Ref: Infusion of unpulsed dendritic cells derived from granulocyte/macrophage colony-stimulating factor-mobilized peripheral blood CD34+ cells and monocytes in patients with advanced carcinoma. PMID: 12857369 Ref: Passage from normal mucosa to adenoma and colon cancer: alteration of normal sCD30 mechanisms regulating TH1/TH2 cell functions. PMID: 14503949 Ref: Magnitude and polarization of P53-specific T-helper immunity in connection to leukocyte infiltration of colorectal tumors. PMID: 14506743 |
Ref: Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs. PMID: 15010828 Ref: Yogurt feeding inhibits promotion and progression of experimental colorectal cancer. PMID: 15039638 Ref: The pattern of cytokine gene expression in human colorectal carcinoma. PMID: 15188028 Ref: Evidence for existence of oligoclonal tumor-infiltrating lymphocytes and predominant production of T helper 1/T cytotoxic 1 type cytokines in gastric and colorectal tumors. PMID: 15201998 Ref: Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer. PMID: 15259008 Ref: [The repetitive immune cell transfer therapy combining non-myelosuppressive chemotherapy for patients with advanced and refractory cancer]. PMID: 15553672 Ref: [Variation of cytokines with administration of chemotherapeutic and immuno-therapeutic drugs for colorectal cancer]. PMID: 15553673 |
Ref: Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13. PMID: 15523692 Ref: Exogenous histamine stimulates colorectal cancer implant growth via immunosuppression in mice. PMID: 15655289 Ref: Interleukin-4 gene transduced tumor cells promote a potent tumor-specific Th1-type response in cooperation with interferon-alpha transduction. PMID: 15772692 Ref: Immune responses in advanced colorectal cancer following repeated intradermal vaccination with the anti-CEA murine monoclonal antibody, PR1A3: results of a phase I study. PMID: 15864608 Ref: Diverse gene expression pattern during 5-fluorouridine-induced apoptosis. PMID: 16010409 Ref: Cytokine expression in colon carcinoma. PMID: 16158955 |
Ref: Predominant T helper type 2-inflammatory responses promote murine colon cancers. PMID: 16331625 Ref: Preoperative oral immune-enhancing nutritional supplementation corrects TH1/TH2 imbalance in patients undergoing elective surgery for colorectal cancer. PMID: 16421661 Ref: Antitumor activity and immune enhancement of murine interleukin-23 expressed in murine colon carcinoma cells. PMID: 16549049 Ref: Reverse of NK cytolysis resistance of type II cytokine predominant-human tumor cells. PMID: 16714222 Ref: Inflammation-related gene polymorphisms and colorectal adenoma. PMID: 16775170 Ref: Vaccination with melanoma lysate-pulsed dendritic cells, of patients with advanced colorectal carcinoma: report from a phase I study. PMID: 16918131 Ref: PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo. PMID: 17018620 |
Ref: Inhibition of angiogenesis by a Semliki Forest virus vector expressing VEGFR-2 reduces tumour growth and metastasis in mice. PMID: 17167497 Ref: Interleukin-4 and interleukin-4 receptor polymorphisms and colorectal cancer risk. PMID: 17258448 Ref: Xenovaccinotherapy for colorectal cancer. PMID: 17258887 Ref: Does impaired TH1/TH2 balance cause postoperative infectious complications in colorectal cancer surgery? PMID: 17292403 Ref: Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer. PMID: 17454884 Ref: The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer. PMID: 17566017 Ref: High incidence of CTLA-4 AA (CT60) polymorphism in renal cell cancer. PMID: 17678726 Ref: Sensitization of colorectal cancer cells to irradiation by IL-4 and IL-10 is associated with inhibition of NF-kappaB. PMID: 17949233 Ref: Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. PMID: 18371377 |
Ref: Lack of interleukin-4 receptor alpha chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice. PMID: 18220315 Ref: IL-4-mediated drug resistance in colon cancer stem cells. PMID: 18235245 Ref: IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells. PMID: 18294957 Ref: Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk. PMID: 18433468 Ref: Interleukin promoter polymorphisms and prognosis in colorectal cancer. PMID: 18448485 Ref: Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients. PMID: 18547033 Ref: Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation. PMID: 18690650 Ref: Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. PMID: 18691581 Ref: 15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity. PMID: 18785202 Ref: Systemic inflammatory response predicts prognosis in patients with advanced-stage colorectal cancer. PMID: 18794066 |
Ref: Differential IL-4/Stat6 activities correlate with differential expression of regulatory genes SOCS-1, SHP-1, and PP2A in colon cancer cells. PMID: 18536936 Ref: EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion. PMID: 19188665 Ref: IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. PMID: 19414811 Ref: DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells. PMID: 19551406 Ref: Suppression of dendritic cells by HMGB1 is associated with lymph node metastasis of human colon cancer. PMID: 19571604 Ref: Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity. PMID: 19585513 Ref: 15-lipoxygenase-1 in colorectal cancer: a review. PMID: 19752603 Ref: Changes in cytokine and biomarker blood levels in patients with colorectal cancer during dendritic cell-based vaccination. PMID: 19863224 Ref: Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi. PMID: 19915149 Ref: Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells. PMID: 19929568 |
Ref: The effect of colorectal cancer upon host peripheral immune cell function. PMID: 19250260 Ref: Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo. PMID: 19669608 Ref: Association between interleukin-4R and TGF-beta1 gene polymorphisms and the risk of colorectal cancer in a Korean population. PMID: 19863607 Ref: Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. PMID: 20061362 Ref: Epithelial interleukin-4 receptor expression promotes colon tumor growth. PMID: 20176658 Ref: Interleukin-4 downregulates CD127 expression and activity on human thymocytes and mature CD8+ T cells. PMID: 20201040 Ref: PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients. PMID: 20229169 Ref: Survivin is regulated by interleukin-4 in colon cancer stem cells. PMID: 20506498 Ref: Soybean and fish oil mixture increases IL-10, protects against DNA damage and decreases colonic inflammation in rats with dextran sulfate sodium (DSS) colitis. PMID: 20615224 Ref: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury. PMID: 20693423 Ref: Dendritic cell vaccination of patients with metastatic colorectal cancer. PMID: 20816019 Ref: [Influence of FOLFOX regimen on the immunologic function in patients with advanced colorectal cancer]. PMID: 20878571 |
Ref: Tumor-reactive CD4+ CD8alphabeta+ CD103+ alphabetaT cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers. PMID: 20824715 Ref: Cytokine disbalance in common human cancers. PMID: 21167870 Ref: Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor gamma expression. PMID: 21295961 Ref: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. PMID: 21303976 Ref: N-acetyl-D-glucosamine-coated polyamidoamine dendrimer promotes tumor-specific B cell responses via natural killer cell activation. PMID: 21349367 Ref: Intraoperative epidural analgesia prevents the early proinflammatory response to surgical trauma. Results from a prospective randomized clinical trial of intraoperative epidural versus general analgesia. PMID: 21479690 Ref: Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. PMID: 21678067 Ref: COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps. PMID: 21730361 Ref: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/beta-catenin/cyclin D1 signaling pathway in rats. PMID: 21764859 Ref: [Inflammatory factors promote the development of colorectal cancer]. PMID: 21873790 Ref: Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer. PMID: 22180364 Ref: Cellular Mechanism of Newly Synthesized Indoledione Derivative-induced Immunological Death of Tumor Cell. PMID: 22346779 Ref: Colorectal cancer stem cells and cell death. PMID: 24212789 |
Ref: Combined treatment with bevacizumab and standard chemotherapy restores abnormal immune parameters in advanced colorectal cancer patients. PMID: 20820907 Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel. PMID: 22305747 Ref: Interleukin-12 inhibits the survival of human colon cancer stem cells in vitro and their tumor initiating capacity in mice. PMID: 22366581 Ref: Effects of oral administration of Butyrivibrio fibrisolvens MDT-1 on the development and healing of atopic dermatitis in NC/Nga mice. PMID: 22377699 Ref: Knockdown of core 1 beta 1, 3-galactosyltransferase prolongs skin allograft survival with induction of galectin-1 secretion and suppression of CD8+ T cells: T synthase knockdown effects on galectin-1 and CD8+ T cells. PMID: 22392045 Ref: Interleukin-4 and CpG oligonucleotide therapy suppresses the outgrowth of tumors by activating tumor-specific Th1-type immune responses. PMID: 22426807 Ref: Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer. PMID: 22441356 Ref: Impact of COX-2, IL-1beta, TNF-alpha, IL-4 and IL-10 on the process of carcinogenesis in the large bowel. PMID: 23359190 Ref: The Effects of Isoproterenol and Propranolol on Cytokine Profile Secretion by Cultured Tumor-infiltrating Lymphocytes Derived from Colorectal Cancer Patients. PMID: 23507624 |
Ref: Association of plasma endotoxin, inflammatory cytokines and risk of colorectal adenomas. PMID: 23442743 Ref: Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis: early target in the anticancer strategy. PMID: 23514809 Ref: The -590C/T polymorphism in the IL-4 gene and the risk of cancer: a meta-analysis. PMID: 23576103 Ref: Influence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells. PMID: 23986643 Ref: Evaluation of immature monocyte-derived dendritic cells generated from patients with colorectal cancer. PMID: 24468592 Ref: Interleukin-13 and its receptors in colorectal cancer (Review). PMID: 24649010 |
Ref: The antibody-based targeted delivery of interleukin-4 and 12 to the tumor neovasculature eradicates tumors in three mouse models of cancer. PMID: 23818211 Ref: Association between IL-4 -589C>T polymorphism and colorectal cancer risk. PMID: 24218339 Ref: Activation of NF-kappaB: bridging the gap between inflammation and cancer in colitis-mediated colon carcinogenesis. PMID: 24269000 Ref: Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4. PMID: 24277698 Ref: Lack of association between interleukin-4 -524C>T polymorphism and colorectal cancer susceptibility. PMID: 24318972 Ref: Polymorphisms of inflammation-related genes and colorectal cancer risk: a population-based case-control study in China. PMID: 24762198 Ref: Exercise effects on polyp burden and immune markers in the ApcMin/+ mouse model of intestinal tumorigenesis. PMID: 24859893 Ref: Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage dysfunction and is associated with colon cancer. PMID: 24882011 Ref: Progastrin represses the alternative activation of human macrophages and modulates their influence on colon cancer epithelial cells. PMID: 24901518 Ref: Potential dual immunomodulatory role of VEGF in ulcerative colitis and colorectal carcinoma. PMID: 25076849 Ref: Extraintestinal helminth infection reduces the development of colitis-associated tumorigenesis. PMID: 25210492 Ref: Transcriptome analysis of CD133-positive stem cells and prognostic value of survivin in colorectal cancer. PMID: 25331798 Ref: Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunity. PMID: 25501829 |
Ref: Helicobacter cinaedi induced typhlocolitis in Rag-2-deficient mice. PMID: 25381744 Ref: Innate immune function after breast, lung, and colorectal cancer surgery. PMID: 25475022 Ref: Dietary inflammatory index and inflammatory gene interactions in relation to colorectal cancer risk in the Bellvitge colorectal cancer case-control study. PMID: 25488145 Ref: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors. PMID: 25875151 Ref: Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma. PMID: 25884547 Ref: Anti-tumour immune effect of oral administration of Lactobacillus plantarum to CT26 tumour-bearing mice. PMID: 25963256 Ref: Artesunate down-regulates immunosuppression from colorectal cancer Colon26 and RKO cells in vitro by decreasing transforming growth factor beta1 and interleukin-10. PMID: 25978851 Ref: Enhancement of the Immunostimulatory Functions of Ex Vivo-Generated Dendritic Cells from Early-Stage Colon Cancer Patients by Consecutive Exposure to Low Doses of Sequential-Kinetic-Activated IL-4 and IL-12. A Preliminary Study. PMID: 26310379 Ref: Radiation and SN38 treatments modulate the expression of microRNAs, cytokines and chemokines in colon cancer cells in a p53-directed manner. PMID: 26556872 |
Ref: Co-operation of alpha-galactosylceramide-loaded tumour cells and TLR9 agonists induce potent anti-tumour responses in a murine colon cancer model. PMID: 26450924 Ref: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer. PMID: 26493186 Ref: Treatment with cyclophosphamide supported by various dendritic cell-based vaccines induces diversification in CD4(+) T cell response against MC38 colon carcinoma. PMID: 26648160 Ref: Expression of COX-2, IL-1beta, TNF-alpha and IL-4 in epithelium of serrated adenoma, adenoma and hyperplastic polyp. PMID: 26925134 Ref: Erythronium japonicum attenuates histopathological lung abnormalities in a mouse model of ovalbumin-induced asthma. PMID: 27035741 Ref: Xenogeneic cell-based vaccine therapy for colorectal cancer: Safety, association of clinical effects with vaccine-induced immune responses. PMID: 27565847 |
Ref: Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways. PMID: 28241877 Ref: Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy. PMID: 28287848 Ref: TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells. PMID: 28376875 Ref: Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. PMID: 28498822 Ref: T cell immunity induced by a bivalent Salmonella-based CEACAM6 and 4-1BBL vaccines in a rat colorectal cancer model. PMID: 28521477 Ref: Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities. PMID: 28535011 Ref: Assessment of neutralizing interleukin-4 effect on CD133 gene expression in colon cancer cell line. PMID: 28578295 Ref: Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response. PMID: 28654863 Ref: Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps. PMID: 28689023 Ref: Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista. PMID: 28711499 Ref: Circulating inflammatory factors associated with worse long-term prognosis in colorectal cancer. PMID: 28974887 Ref: IL-8 Is Involved in Estrogen-Related Receptor alpha-Regulated Proliferation and Migration of Colorectal Cancer Cells. PMID: 28993941 Ref: Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features. PMID: 29085228 Ref: Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development in Apc(min/+) mice. PMID: 29228651 Ref: Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice. PMID: 29326691 Ref: Analysis of 12 variants in the development of gastric and colorectal cancers. PMID: 29358861 |
Ref: CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease. PMID: 29304229 Ref: PKN2 in colon cancer cells inhibits M2 phenotype polarization of tumor-associated macrophages via regulating DUSP6-Erk1/2 pathway. PMID: 29368606 Ref: Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages. PMID: 29690889 Ref: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer. PMID: 29801973 Ref: E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells. PMID: 29901191 Ref: Antitumor Effects of Umbelliprenin in a Mouse Model of Colorectal Cancer. PMID: 30127820 Ref: Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis. PMID: 30202097 Ref: Association study on IL-4, IL-4Ralpha and IL-13 genetic polymorphisms in Swedish patients with colorectal cancer. PMID: 30227113 Ref: Positive correlation between interleukin-1 receptor antagonist gene 86bp VNTR polymorphism and colorectal cancer susceptibility: a case-control study. PMID: 30382562 |