Primary Site >> Colorectal Cancer

Gene >> IL1R1

  • 1994
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  • 2018
Ref: Caco-2 cells express type I interleukin-1 receptors: ligand binding enhances proliferation.
PMID: 7810657
Ref: Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma.
PMID: 8566049
Ref: Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.
PMID: 22791816
Ref: Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
PMID: 26344057
Ref: miR-148a inhibits colitis and colitis-associated tumorigenesis in mice.
PMID: 28960206
Ref: Interleukin-1 Signaling Mediates Obesity-Promoted Elevations in Inflammatory Cytokines, Wnt Activation, and Epithelial Proliferation in the Mouse Colon.
PMID: 30328795