Primary Site >> Pancreatic Cancer
Gene >> IL1B
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Ref: Importance of E-selectin (ELAM-1) and sialyl Lewis(a) in the adhesion of pancreatic carcinoma cells to activated endothelium. PMID: 7687590 Ref: Cytokine regulation of cell-to-cell interactions in lymphokine-activated killer cell cytotoxicity in vitro. PMID: 8093857 |
Ref: [Molecular mechanism in hematogenous metastasis of pancreas carcinoma--possible implication of tumor-derived cytokine in a cell-to-cell interaction of pancreas carcinoma and vascular endothelial cells]. PMID: 7525435 Ref: Lymphokine-activated killer cytotoxicity against pancreas adenocarcinoma cell lines and vascular endothelial cells. PMID: 7804431 |
Ref: E-selectin expression induced by pancreas-carcinoma-derived interleukin-1 alpha results in enhanced adhesion of pancreas-carcinoma cells to endothelial cells. PMID: 7532161 Ref: Tumor-associated lymphocytes (TAL) are competent to produce higher levels of cytokines in neoplastic pleural and peritoneal effusions than those found in sera and are able to release into culture higher levels of IL-2 and IL-6 than those released by PBMC. PMID: 8528743 |
Ref: Human intestinal Vdelta1+ lymphocytes recognize tumor cells of epithelial origin. PMID: 8666926 Ref: In vivo murine tumor gene delivery and expression by systemic recombinant vaccinia virus encoding interleukin-1beta. PMID: 9166494 |
Ref: Involvement of adhesion molecules in metastasis of SW1990, human pancreatic cancer cells. PMID: 9486777 Ref: Nitric oxide-induced apoptosis in human pancreatic carcinoma cell lines is associated with a G1-arrest and an increase of the cyclin-dependent kinase inhibitor p21WAF1/CIP1. PMID: 9716178 Ref: Portal but not peripheral serum levels of interleukin 6 could interfere with glucose metabolism in patients with pancreatic cancer. PMID: 9853701 |
Ref: Cytokines modulate MIA PaCa 2 and CAPAN-1 adhesion to extracellular matrix proteins. PMID: 10547196 |
Ref: Transforming growth factor-beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines. PMID: 10707928 Ref: Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kappaB. PMID: 10822373 Ref: The expression of chemokine genes correlates with nuclear factor-kappaB activation in human pancreatic cancer cell lines. PMID: 10881930 |
Ref: Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia. PMID: 11962246 |
Ref: Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines. PMID: 11830551 Ref: The role of oxygen-derived free radicals and nitric oxide in cytokine-induced antiproliferation of pancreatic cancer cells. PMID: 11854621 |
Ref: Experimental studies of serum cytokine concentration following pancreatic electrolytic ablation. PMID: 12552236 Ref: The CC chemokine MCP-1/CCL2 in pancreatic cancer progression: regulation of expression and potential mechanisms of antimalignant activity. PMID: 14612545 |
Ref: The lack of a systemic inflammatory response syndrome supports the safety of pancreatic electrolysis: experimental studies. PMID: 14732357 Ref: Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. PMID: 14973050 Ref: [Autocrine IL-1beta secretion leads to NF-kappabeta-mediated chemoresistance in pancreatic carcinoma cells in vivo]. PMID: 15085288 Ref: Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis. PMID: 15526319 |
Ref: Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells. PMID: 15735017 Ref: Intrahepatic cholestasis as a paraneoplastic syndrome associated with pheochromocytoma. PMID: 15887866 Ref: Pancreatic cancer cells invasiveness is mainly affected by interleukin-1beta not by transforming growth factor-beta1. PMID: 16398405 |
Ref: Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival. PMID: 16094523 Ref: Acquired chemoresistance in pancreatic carcinoma cells: induced secretion of IL-1beta and NO lead to inactivation of caspases. PMID: 16474845 Ref: The expression of adhesion molecules and the influence of inflammatory cytokines on the adhesion of human pancreatic carcinoma cells to mesothelial monolayers. PMID: 16670622 |
Ref: Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. PMID: 17332938 Ref: Mechanisms of skeletal muscle degradation and its therapy in cancer cachexia. PMID: 17455154 Ref: Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-alpha and leukemia inhibitory factor in pancreatic carcinoma cells: Impact of CXCL-8 as an autocrine growth factor. PMID: 17671691 |
Ref: Mononuclear cell-derived interleukin-1 beta confers chemoresistance in pancreatic cancer cells by upregulation of cyclooxygenase-2. PMID: 18571585 Ref: Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells. PMID: 18639630 |
Ref: Interleukin 1 beta gene promoter SNPs are associated with risk of pancreatic cancer. PMID: 19251436 Ref: Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer: a multicentre prospective randomized trial. PMID: 19309495 Ref: Interleukin-32 expression in the pancreas. PMID: 19386602 Ref: Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. PMID: 19671674 Ref: Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes. PMID: 19692203 Ref: Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. PMID: 19768141 |
Ref: Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats. PMID: 19900821 Ref: Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis. PMID: 20065943 Ref: Protective effect of cyclosporin A on brain injury in rats with acute necrotic pancreatitis. PMID: 20561905 Ref: Nuclear expression of interleukin-33 in pancreatic stellate cells. PMID: 20689058 |
Ref: Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer. PMID: 21339327 Ref: STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice. PMID: 21991388 |
Ref: Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells. PMID: 22293948 Ref: Gene expression profiling and pathway analysis identify the integrin signaling pathway to be altered by IL-1beta in human pancreatic cancer cells: role of JNK. PMID: 22313544 Ref: [Protective effects and possible mechanism of lipoxin A(4) analogue in rats with acute pancreatitis]. PMID: 22781577 Ref: Protective effects of alpha-pinene in mice with cerulein-induced acute pancreatitis. PMID: 22982349 Ref: In vitro cytokine profiles and viability of different human cells treated with whole cell lysate of Mycobacterium avium subsp. paratuberculosis. PMID: 23006537 Ref: Role of janus kinase/signal transducers and activators of transcription in the pathogenesis of pancreatitis and pancreatic cancer. PMID: 23170143 |
Ref: Impact of cytokines on diffuse splenic 18F-fluorodeoxyglucose uptake during positron emission tomography/computed tomography. PMID: 23076270 Ref: Disrupting cytokine signaling in pancreatic cancer: a phase I/II study of etanercept in combination with gemcitabine in patients with advanced disease. PMID: 23429495 Ref: Dimethylaminoparthenolide and gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancer. PMID: 23590467 Ref: Serum levels of IL-6 and IL-1beta can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer. PMID: 23591198 |
Ref: Depression, cytokines, and pancreatic cancer. PMID: 24136882 Ref: Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy? PMID: 24163144 Ref: Complementary induction of immunogenic cell death by oncolytic parvovirus H-1PV and gemcitabine in pancreatic cancer. PMID: 24574398 Ref: Serum cytokine biomarker panels for discriminating pancreatic cancer from benign pancreatic disease. PMID: 24884871 Ref: [Impact of chemotherapies on immunosuppression and discovery of new therapeutic targets]. PMID: 24899072 Ref: Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. PMID: 24912820 Ref: Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. PMID: 25356049 Ref: Effects of a novel cytokine haemoadsorbtion system on inflammatory response in septic shock after cephalic pancreatectomy - a case report. PMID: 28913446 |
Ref: Measuring sickness behavior in the context of pancreatic cancer. PMID: 25659492 Ref: Inflammatory cytokines regulate the expression of glycosyltransferases involved in the biosynthesis of tumor-associated sialylated glycans in pancreatic cancer cell lines. PMID: 25934648 Ref: Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. PMID: 25993999 Ref: Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. PMID: 26641266 |
Ref: Combined inhibition of IL1, CXCR1/2, and TGFbeta signaling pathways modulates in-vivo resistance to anti-VEGF treatment. PMID: 26473526 Ref: Subclinical Inflammation and Endothelial Dysfunction in Patients with Chronic Pancreatitis and Newly Diagnosed Pancreatic Cancer. PMID: 26597191 Ref: Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. PMID: 27246539 Ref: Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats. PMID: 27297425 Ref: Hyperglycemia, tumorigenesis, and chronic inflammation. PMID: 27931833 |
Ref: Apelin Regulates Nuclear Factor-kappaB's Involvement in the Inflammatory Response of Pancreatitis. PMID: 27846147 Ref: Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia. PMID: 27901481 Ref: A predictive model of inflammatory markers and patient-reported symptoms for cachexia in newly diagnosed pancreatic cancer patients. PMID: 28111717 Ref: Pathogenic mechanisms of pancreatitis. PMID: 28217371 Ref: Intestinal permeability changes, systemic endotoxemia, inflammatory serum markers and sepsis after Whipple's operation for carcinoma of the pancreas head. PMID: 28803860 Ref: Immunomodulation after radiofrequency ablation of locally advanced pancreatic cancer by monitoring the immune response in 10 patients. PMID: 29037917 Ref: Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer. PMID: 29228654 Ref: Apolipoprotein A-I mimetic peptide 4F suppresses tumor-associated macrophages and pancreatic cancer progression. PMID: 29245934 |
Ref: NFkappaB-Mediated Invasiveness in CD133(+) Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling. PMID: 28970361 Ref: Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1beta from activated macrophages leads to poor prognosis in pancreatic cancer. PMID: 29224225 Ref: Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naive pancreatic cancer patients. PMID: 29316343 Ref: Tumor-Stroma IL1beta-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer. PMID: 29363544 Ref: Antimicrobial Peptide Human Neutrophil Peptide 1 as a Potential Link Between Chronic Inflammation and Ductal Adenocarcinoma of the Pancreas. PMID: 29683978 Ref: Impact of targeting transforming growth factor beta-2 with antisense OT-101 on the cytokine and chemokine profile in patients with advanced pancreatic cancer. PMID: 29785126 Ref: Nrf2 activation drive macrophages polarization and cancer cell epithelial-mesenchymal transition during interaction. PMID: 30180849 Ref: Serum levels of IL-6, IL-8, and IL-10 are indicators of prognosis in pancreatic cancer. PMID: 30304975 Ref: Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages. PMID: 30383833 |