Primary Site >> Colorectal Cancer

Gene >> IL1A

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Ref: Correlation between human cell growth response to interleukin 1 and receptor binding.
PMID: 2970890
Ref: Membrane-associated interleukin 1 alpha as a mediator of tumor cell killing by human blood monocytes fixed with paraformaldehyde.
PMID: 2463072
Ref: Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state.
PMID: 1913671
Ref: Murine endothelioma cell lines transformed by polyoma middle T oncogene as target for and producers of cytokines.
PMID: 1918946
Ref: Impaired cytokine production in whole blood cell cultures from patients with colorectal carcinomas as compared to benign colorectal tumors and controls.
PMID: 1403351
Ref: Mechanisms of Kupffer cell cytotoxicity in vitro against the syngeneic murine colon adenocarcinoma line MCA26.
PMID: 8315355
Ref: Interleukin-10 production by human carcinoma cell lines and its relationship to interleukin-6 expression.
PMID: 8344757
Ref: Superantigen-induced cytokines suppress growth of human colon-carcinoma cells.
PMID: 8509223
Ref: Enhanced cytotoxicity with interleukin-1 alpha and 5-fluorouracil in HCT116 colon cancer cells.
PMID: 7787251
Ref: Expression of cytokines, TNF-alpha and IL-1 alpha, in MAM acetate and 1-hydroxyanthraquinone-induced colon carcinogenesis of rats.
PMID: 8149497
Ref: The role of cytokines in mediating the bystander effect using HSV-TK xenogeneic cells.
PMID: 7600527
Ref: The correlation of thymidine phosphorylase activity with the expression of interleukin 1 alpha, interferon alpha and interferon gamma in human colorectal carcinoma.
PMID: 7656244
Ref: Establishment and characterization of cachexia-inducing and -non-inducing clones of murine colon 26 carcinoma.
PMID: 7759158
Ref: Mechanisms of colon cancer binding to substratum and cells.
PMID: 8769278
Ref: IL-1alpha gene-transfected human melanoma cells increase tumor-cell adhesion to endothelial cells and their retention in the lung of nude mice.
PMID: 8824559
Ref: [The relation between pyrimidine nucleoside phosphorylase (PyNPase) activity in colorectal cancer tissues and pathological effects].
PMID: 9126307
Ref: IL-2-Activated Killer Cells and Native Cytokines in Treatment of Patients with Advanced Cancer.
PMID: 12687071
Ref: The significance of an increase in soluble interleukin-2 receptor level in colorectal cancer and its biological regulating role in the physiological switching of the immune response cytokine network from TH1 to TH2 and back.
PMID: 9439647
Ref: Active specific immunotherapy for metastatic colorectal carcinoma: phase I study of an allogeneic cell vaccine plus low-dose interleukin-1 alpha.
PMID: 10335485
Ref: Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism.
PMID: 10358077
Ref: Colitis-related rat colon carcinogenesis induced by 1-hydroxy-anthraquinone and methylazoxymethanol acetate (Review).
PMID: 10767359
Ref: Interaction of tumor cells with vascular endothelia: role of platelet-activating factor.
PMID: 11206844
Ref: In vivo destruction of tumor tissue by cryoablation can induce inhibition of secondary tumor growth: an experimental study.
PMID: 11336489
Ref: Induction of alpha1-acid glycoprotein mRNA by cytokines and differentiation in human colon carcinoma cell.
PMID: 11355696
Ref: Group IID heparin-binding secretory phospholipase A(2) is expressed in human colon carcinoma cells and human mast cells and up-regulated in mouse inflammatory tissues.
PMID: 12047378
Ref: In vivo gene transfer of murine interleukin-4 inhibits colon-26-mediated cancer cachexia in mice.
PMID: 12529962
Ref: Combined effect of hydrogen peroxide induced oxidative stress and IL-1 alpha on IL-8 production in CaCo-2 cells (a human colon carcinoma cell line) and normal intestinal epithelial cells.
PMID: 12875365
Ref: Human colon carcinomas constitutively express and shed type II IL-1 receptor, an IL-1 antagonist.
PMID: 14560993
Ref: Zerumbone, an anti-inflammatory phytochemical, induces expression of proinflammatory cytokine genes in human colon adenocarcinoma cell lines.
PMID: 15630177
Ref: Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia.
PMID: 15920164
Ref: The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the northeast of Scotland.
PMID: 16030091
Ref: Cytokine expression in colon carcinoma.
PMID: 16158955
Ref: Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice.
PMID: 16424015
Ref: Prostaglandin E2 induces the expression of IL-1alpha in colon cancer cells.
PMID: 17371964
Ref: HETEs enhance IL-1-mediated COX-2 expression via augmentation of message stability in human colonic myofibroblasts.
PMID: 17640979
Ref: Inhibition of proinflammatory cytokine-induced invasiveness of HT-29 cells by chitosan oligosaccharide.
PMID: 18167453
Ref: Cancer cell-derived IL-1alpha induces IL-8 release in endothelial cells.
PMID: 17622559
Ref: Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
PMID: 18064302
Ref: GPx2 counteracts PGE2 production by dampening COX-2 and mPGES-1 expression in human colon cancer cells.
PMID: 18479189
Ref: Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer.
PMID: 19119184
Ref: Differences in cytokine levels due to gender in colorectal cancer patients.
PMID: 20116278
Ref: Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival.
PMID: 20162422
Ref: Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-2, and IL-8.
PMID: 20846456
Ref: The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer.
PMID: 20920199
Ref: Intraoperative epidural analgesia prevents the early proinflammatory response to surgical trauma. Results from a prospective randomized clinical trial of intraoperative epidural versus general analgesia.
PMID: 21479690
Ref: Gallotannin inhibits NFkB signaling and growth of human colon cancer xenografts.
PMID: 21532339
Ref: Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array.
PMID: 22363134
Ref: [Perioperative immunologic changes in colorectal cancer patients].
PMID: 22480118
Ref: IL-1RN +2018T>C polymorphism is correlated with colorectal cancer.
PMID: 23192617
Ref: Hemoptysis and acute respiratory syndrome (ARDS) as delayed-type hypersensitivity after FOLFOX4 plus bevacizumab treatment.
PMID: 24229039
Ref: Structurally characterized arabinogalactan from Anoectochilus formosanus as an immuno-modulator against CT26 colon cancer in BALB/c mice.
PMID: 24315348
Ref: Expression profiles of 507 proteins from a biotin label-based antibody array in human colorectal cancer.
PMID: 24366523
Ref: Association between the IFN-gamma and IL-1 genetic polymorphisms and colorectal cancer in the Chinese Han population.
PMID: 24840847
Ref: Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
PMID: 25218594
Ref: Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach.
PMID: 25271420
Ref: Cobalt chloride induces necroptosis in human colon cancer HT-29 cells.
PMID: 25824798
Ref: Obesity and Obese-related Chronic Low-grade Inflammation in Promotion of Colorectal Cancer Development.
PMID: 26028066
Ref: Lack of association between an insertion/deletion polymorphism in IL1A and risk of colorectal cancer.
PMID: 26345777
Ref: The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116.
PMID: 26519257
Ref: IL-1 in Colon Inflammation, Colon Carcinogenesis and Invasiveness of Colon Cancer.
PMID: 26686225
Ref: [Effect of colon cancer cell-derived IL-1alpha on the migration and proliferation of vascular endothelial cells].
PMID: 26887509
Ref: Antitumor Activity of Total Flavonoids from Daphne genkwa in Colorectal Cancer.
PMID: 26646778
Ref: Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
PMID: 26951793
Ref: MK2: an unrecognized regulator of tumor promoting macrophages in colorectal cancer?
PMID: 26998523
Ref: Inflammatory bowel disease, colorectal cancer and type 2 diabetes mellitus: The links.
PMID: 27051585
Ref: Stromal CCR6 drives tumor growth in a murine transplantable colon cancer through recruitment of tumor-promoting macrophages.
PMID: 27622061
Ref: A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors.
PMID: 27708224
Ref: IL-33 regulates the IgA-microbiota axis to restrain IL-1alpha-dependent colitis and tumorigenesis.
PMID: 27775548
Ref: Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
PMID: 27825961
Ref: Inflammasomes and Cancer.
PMID: 28093447
Ref: MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study.
PMID: 28094194
Ref: A food-based approach that targets interleukin-6, a key regulator of chronic intestinal inflammation and colon carcinogenesis.
PMID: 28193578
Ref: Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma.
PMID: 28533893
Ref: Chemopreventive effects of Ku-jin tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis.
PMID: 29162930
Ref: Analysis of 12 variants in the development of gastric and colorectal cancers.
PMID: 29358861
Ref: The mechanisms linking obesity to colon cancer: An overview.
PMID: 29428365
Ref: Association between an insertion/deletion polymorphism in the interleukin-1alpha gene and the risk of colorectal cancer in a Chinese population.
PMID: 30016900
Ref: A Novel Role for the Interleukin-1 Receptor Axis in Resistance to Anti-EGFR Therapy.
PMID: 30261609
Ref: Senescence marker protein 30 protects intestinal epithelial cells against inflammation-induced cell death by enhancing Nrf2 activity.
PMID: 30266650