Primary Site >> Pancreatic Cancer

Gene >> IL18

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Ref: Antitumor effect of human pancreatic cancer cells transduced with cytokine genes which activate Th1 helper T cells.
PMID: 9568099
Ref: The immunotherapeutic effect of dendritic cells vaccine modified with interleukin-18 gene and tumor cell lysate on mice with pancreatic carcinoma.
PMID: 12378640
Ref: Human pancreatic carcinoma cells secrete bioactive interleukin-18 after treatment with 5-fluorouracil: implications for anti-tumor immune response.
PMID: 15684607
Ref: Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival.
PMID: 16094523
Ref: Systemic immune dysfunction in pancreatic cancer patients.
PMID: 17235586
Ref: Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes.
PMID: 19692203
Ref: Blocking NF-kappaB Is Essential for the Immunotherapeutic Effect of Recombinant IL18 in Pancreatic Cancer.
PMID: 27297583
Ref: Pathogenic mechanisms of pancreatitis.
PMID: 28217371
Ref: Identification of molecular mechanisms of glutamine in pancreatic cancer.
PMID: 29163679
Ref: Regulatory B cells induced by pancreatic cancer cell-derived interleukin-18 promote immune tolerance via the PD-1/PD-L1 pathway.
PMID: 29599908