Primary Site >> Colorectal Cancer
Gene >> IL17A
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Ref: Control of tumor development by intratumoral cytokines. PMID: 10397168 |
Ref: Prestimulation of monocytes by the cytokines GM-CSF or IL-2 enhances the antibody dependent cellular cytotoxicity of monoclonal antibody 17-1A. PMID: 11031784 |
Ref: Expression of interleukin-17 in human colorectal cancer. PMID: 17201135 |
Ref: High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas. PMID: 17965063 |
Ref: Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma. PMID: 19737943 |
Ref: IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. PMID: 20228195 Ref: In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. PMID: 20308560 Ref: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury. PMID: 20693423 Ref: Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer. PMID: 20885960 |
Ref: Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer. PMID: 20952660 Ref: Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques. PMID: 21150855 Ref: Microbial dysbiosis in colorectal cancer (CRC) patients. PMID: 21297998 Ref: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. PMID: 21303976 Ref: IL-17+ regulatory T cells in the microenvironments of chronic inflammation and cancer. PMID: 21357259 Ref: IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. PMID: 21396350 Ref: Involvement of interleukin-21 in the regulation of colitis-associated colon cancer. PMID: 21987656 |
Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Role of IL-17A in the development of colitis-associated cancer. PMID: 22354874 Ref: Immunoregulatory mechanisms underlying prevention of colitis-associated colorectal cancer by probiotic bacteria. PMID: 22511958 Ref: LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer. PMID: 22879386 Ref: IL-17A in the tumor microenvironment of the human colorectal adenoma-carcinoma sequence. PMID: 22989213 Ref: The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers. PMID: 22994684 Ref: Expression of RORgammat marks a pathogenic regulatory T cell subset in human colon cancer. PMID: 23241743 Ref: The Effects of Isoproterenol and Propranolol on Cytokine Profile Secretion by Cultured Tumor-infiltrating Lymphocytes Derived from Colorectal Cancer Patients. PMID: 23507624 |
Ref: Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Galphai2-deficient mouse. PMID: 22962436 Ref: Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. PMID: 23002055 Ref: Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model. PMID: 23589566 Ref: The role of interleukin-17A in colorectal tumorigenesis. PMID: 23701420 Ref: The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer. PMID: 23773923 Ref: [Comparison of local immune microenvironment between liver-metastasis colorectal cancer and non-liver-metastasis colorectal cancer]. PMID: 23801208 Ref: Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer. PMID: 23805328 Ref: [Effect of Achyranthes bidentata polysaccharides stimulated dendritic cells co-cultured with cytokine induced killer cells against SW480 cells]. PMID: 23847957 Ref: TNFalpha and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells. PMID: 23866118 Ref: Fish oil decreases C-reactive protein/albumin ratio improving nutritional prognosis and plasma fatty acid profile in colorectal cancer patients. PMID: 23888317 Ref: Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer. PMID: 23912334 Ref: Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-gamma. PMID: 24040001 Ref: Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. PMID: 24323355 |
Ref: Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. PMID: 24232001 Ref: Significant association between IL23R and IL17F polymorphisms and clinical features of colorectal cancer. PMID: 24440568 Ref: Correlation between genetic polymorphisms within IL-1B and TLR4 genes and cancer risk in a Russian population: a case-control study. PMID: 24446182 Ref: Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells. PMID: 24480808 Ref: Intratumoral regulatory T cells are associated with suppression of colorectal carcinoma metastasis after resection through overcoming IL-17 producing T cells. PMID: 24487033 Ref: [Correlations between tumor infiltrating Th17 cells and clinicopathological parameters in patients with colorectal cancer]. PMID: 24606752 Ref: Effect of interleukin-17 on gene expression profile of fibroblasts from Crohn's disease patients. PMID: 24637010 Ref: Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. PMID: 24651526 Ref: Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. PMID: 24677375 Ref: Significant association between interleukin-17A polymorphism and colorectal cancer. PMID: 24699997 Ref: gammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. PMID: 24816404 Ref: Colorectal cancer progression is associated with accumulation of Th17 lymphocytes in tumor tissues and increased serum levels of interleukin-6. PMID: 24990228 Ref: The effect of immune microenvironment on the progression and prognosis of colorectal cancer. PMID: 25034363 Ref: Potential dual immunomodulatory role of VEGF in ulcerative colitis and colorectal carcinoma. PMID: 25076849 Ref: Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer. PMID: 25187386 Ref: Association between Toll-like receptor 4 and interleukin 17 gene polymorphisms and colorectal cancer susceptibility in Northeast China. PMID: 25216863 Ref: Role of IL-17 and IL-22 in autoimmunity and cancer. PMID: 25398491 Ref: IL-17 cuts to the chase in colon cancer. PMID: 25526302 Ref: Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis. PMID: 25526314 Ref: Innate gammadeltaT17 cells convert cancer-elicited inflammation into immunosuppression through myeloid-derived suppressor cells. PMID: 25610744 |
Ref: Elevated proinflammatory cytokine IL-17A in the adjacent tissues along the adenoma-carcinoma sequence. PMID: 24859972 Ref: The frequency of Th17 and Th22 cells in patients with colorectal cancer at pre-operation and post-operation. PMID: 25026244 Ref: Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. PMID: 25174402 Ref: Therapeutic efficacy of IL-17A antibody injection in preventing the development of colitis associated carcinogenesis in mice. PMID: 25239511 Ref: Involvement of heat shock protein a4/apg-2 in refractory inflammatory bowel disease. PMID: 25437815 Ref: Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. PMID: 25667306 Ref: Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression. PMID: 25680555 Ref: Human papillomavirus infection correlates with inflammatory Stat3 signaling activity and IL-17 level in patients with colorectal cancer. PMID: 25706309 Ref: RORgammat(+) hematopoietic cells are necessary for tumor cell proliferation during colitis-associated tumorigenesis in mice. PMID: 25820779 Ref: Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses. PMID: 25834404 Ref: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors. PMID: 25875151 Ref: Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma. PMID: 25884547 Ref: The immune microenvironment of the colorectal tumor: Involvement of immunity genes and microRNAs belonging to the TH17 pathway. PMID: 25911397 Ref: Anti-tumour immune effect of oral administration of Lactobacillus plantarum to CT26 tumour-bearing mice. PMID: 25963256 Ref: [Compound K suppresses myeloid-derived suppressor cells in a mouse model bearing CT26 colorectal cancer xenograft]. PMID: 26018276 Ref: Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer. PMID: 26047578 Ref: Involvement of IL17A, IL17F and IL23R Polymorphisms in Colorectal Cancer Therapy. PMID: 26083022 Ref: Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis. PMID: 26201900 Ref: Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-gamma. PMID: 26297765 Ref: Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice. PMID: 26344057 Ref: Vitamin D, Inflammation, and Colorectal Cancer Progression: A Review of Mechanistic Studies and Future Directions for Epidemiological Studies. PMID: 26396142 Ref: IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer. PMID: 26429861 Ref: The IL-23 to IL-17 cascade inflammation-related cancers. PMID: 26457610 Ref: Moderately Fermentable Potato Fiber Attenuates Signs and Inflammation Associated with Experimental Colitis in Mice. PMID: 26491118 Ref: IL-17A Levels in the Sera of Patients with Gastric Cancer Show Limited Elevation. PMID: 26514504 Ref: Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer. PMID: 26645238 |
Ref: Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer. PMID: 25838550 Ref: Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer. PMID: 25994220 Ref: Distinctive expression pattern of interleukin-17 cytokine family members in colorectal cancer. PMID: 26304506 Ref: Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice. PMID: 26502315 Ref: Deficiency of IL-17A, but not the prototypical Th17 transcription factor RORgammat, decreases murine spontaneous intestinal tumorigenesis. PMID: 26559812 Ref: A Novel Immune Marker Model Predicts Oncological Outcomes of Patients with Colorectal Cancer. PMID: 26581202 Ref: Overexpression of interleukins IL-17 and IL-8 with poor prognosis in colorectal cancer induces metastasis. PMID: 26678893 Ref: Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer. PMID: 26712311 Ref: Circulating and tumor-infiltrating mucosal associated invariant T (MAIT) cells in colorectal cancer patients. PMID: 26837580 Ref: Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis. PMID: 26880802 Ref: Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice. PMID: 26884164 Ref: Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment. PMID: 26908749 Ref: Expression of CD27, CD28 and IL-17A in peripheral blood from patients with colorectal carcinoma. PMID: 26957265 Ref: Enrichment of Inflammatory IL-17 and TNF-alpha Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1. PMID: 27014625 Ref: IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kappaB-Mediated MMP Expression. PMID: 27098148 Ref: Induction of immunogenic cell death by radiation-upregulated karyopherin alpha 2 in vitro. PMID: 27107455 Ref: Feedback mechanisms between M2 macrophages and Th17 cells in colorectal cancer patients. PMID: 27235120 Ref: Decreased Anti-Tumor Cytotoxic Immunity among Microsatellite-Stable Colon Cancers from African Americans. PMID: 27310868 Ref: Microsatellite instability as a predictive factor for immunotherapy in malignant melanoma. PMID: 27372860 Ref: The Membrane-Bound Form of IL-17A Promotes the Growth and Tumorigenicity of Colon Cancer Cells. PMID: 27378226 Ref: Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlbeta (RELMbeta) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility. PMID: 27397737 Ref: Association between circulating galectin-3 levels and the immunological, inflammatory and nutritional parameters in patients with colorectal cancer. PMID: 27446542 Ref: Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer. PMID: 27517754 Ref: Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer. PMID: 27622025 Ref: TGF-beta1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis. PMID: 27626488 Ref: Circulating and tissue galectin-1 and galectin-3 in colorectal carcinoma: association with clinicopathological parameters, serum CEA, IL-17 and IL23. PMID: 27685917 Ref: Retraction Note to: Overexpression of interleukins IL-17 and IL-8 with poor prognosis in colorectal cancer induces metastasis. PMID: 27826943 Ref: IL-17A produced by peritoneal macrophages promote the accumulation and function of granulocytic myeloid-derived suppressor cells in the development of colitis-associated cancer. PMID: 27909978 Ref: Functional impairment of infiltrating T cells in human colorectal cancer. PMID: 27999752 Ref: Effect of IL-17 in the development of colon cancer in mice. PMID: 28101230 Ref: Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells. PMID: 28439450 |
Ref: Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. PMID: 27375020 Ref: Anti-inflammatory natural product goniothalamin reduces colitis-associated and sporadic colorectal tumorigenesis. PMID: 27797827 Ref: T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. PMID: 27935860 Ref: Local and systemic Th17 immune response associated with advanced stage colon cancer. PMID: 27993206 Ref: The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3. PMID: 28160571 Ref: Deficiency of the immunostimulatory cytokine IL-21 promotes intestinal neoplasia via dysregulation of the Th1/Th17 axis. PMID: 28197386 Ref: A possible association of baseline serum IL-17A concentrations with progression-free survival of metastatic colorectal cancer patients treated with a bevacizumab-based regimen. PMID: 28347290 Ref: Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. PMID: 28385737 Ref: Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors. PMID: 28483840 Ref: Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice. PMID: 28823860 Ref: Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats. PMID: 28848081 Ref: Upregulation of Treg-Related Genes in Addition with IL6 Showed the Significant Role for the Distant Metastasis in Colorectal Cancer. PMID: 28868572 Ref: Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice. PMID: 28881611 Ref: Suppression Colitis and Colitis-Associated Colon Cancer by Anti-S100a9 Antibody in Mice. PMID: 29326691 |
Ref: Unique invariant natural killer T cells promote intestinal polyps by suppressing TH1 immunity and promoting regulatory T cells. PMID: 28401935 Ref: MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors. PMID: 29031499 Ref: Monoclonal Antibodies Targeting the IL-17/IL-17RA Axis: An Opportunity to Improve the Efficiency of Anti-VEGF Therapy in Fighting Metastatic Colorectal Cancer? PMID: 29153431 Ref: Th17 cytokine profiling of colorectal cancer patients with or without enterovirus 71 antigen expression. PMID: 29175261 Ref: Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe? PMID: 29470597 Ref: Andrographolide presents therapeutic effect on ulcerative colitis through the inhibition of IL-23/IL-17 axis. PMID: 29511440 Ref: Expression and location of IL-17A, E, F and their receptors in colorectal adenocarcinoma: Comparison with benign intestinal disease. PMID: 29548809 Ref: Cardiotrophin-1 attenuates experimental colitis in mice. PMID: 29572384 Ref: Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response. PMID: 29630898 Ref: Association of interleukin-17A polymorphisms with the risk of colorectal cancer: A case-control study. PMID: 29689450 Ref: Analysis of Th22, Th17 and CD4(+)cells co-producing IL-17/IL-22 at different stages of human colon cancer. PMID: 29710675 Ref: Prognostic roles for IL-2-producing and CD69(+) T cell subsets in colorectal cancer patients. PMID: 29752720 Ref: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer. PMID: 29801973 Ref: Immuno-therapeutic potential of Schistosoma mansoni and Trichinella spiralis antigens in a murine model of colon cancer. PMID: 29808307 Ref: Levels of peripheral Th17 cells and serum Th17-related cytokines in patients with colorectal cancer: a meta-analysis. PMID: 29808807 Ref: Association between polymorphisms of interleukin-17A G197A and interleukin-17F A7488G and risk of colorectal cancer. PMID: 29970680 Ref: beta-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC. PMID: 30186819 Ref: Roles for Interleukin 17 and Adaptive Immunity in Pathogenesis of Colorectal Cancer. PMID: 30218667 Ref: IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression. PMID: 30233234 Ref: Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A. PMID: 30279518 Ref: Single probiotic supplement suppresses colitis-associated colorectal tumourigenesis by modulating inflammatory development and microbial homeostasis. PMID: 30357910 |