Primary Site >> Colorectal Cancer

Gene >> IHH

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Ref: Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation.
PMID: 14770182
Ref: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico.
PMID: 15645142
Ref: Comparative genomics on Sonic hedgehog orthologs.
PMID: 16142377
Ref: WNT antagonist, SFRP1, is Hedgehog signaling target.
PMID: 16328026
Ref: Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
PMID: 17089004
Ref: Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
PMID: 17683069
Ref: Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa.
PMID: 18405344
Ref: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation.
PMID: 19280222
Ref: Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters.
PMID: 19856079
Ref: Estrogen receptor alpha or beta loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFbeta and HNF3beta signaling.
PMID: 24104551
Ref: Expression of Indian hedgehog is negatively correlated with APC gene mutation in colorectal tumors.
PMID: 25232400
Ref: Colorectal Cancer Metastases Settle in the Hepatic Microenvironment Through alpha5beta1 Integrin.
PMID: 25857463
Ref: Influence of components of tumour microenvironment on the response of HCT-116 colorectal cancer to the ruthenium-based drug NAMI-A.
PMID: 28064102