Primary Site >> Esophagus Cancer

Gene >> IGF2

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Ref: Effects of various growth factors on growth of a cloned human esophageal squamous cancer cell line in a protein-free medium.
PMID: 1746916
Ref: Relaxation of insulin-like growth factor 2 gene imprinting in esophageal cancer.
PMID: 8945613
Ref: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
PMID: 9809981
Ref: Analysis of genomic imprinting of insulin-like growth factor 2 in colorectal cancer.
PMID: 11053988
Ref: LOI of IGF2 is associated with esophageal cancer and linked to methylation status of IGF2 DMR.
PMID: 17310846
Ref: Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.
PMID: 21668571
Ref: Id1-induced IGF-II and its autocrine/endocrine promotion of esophageal cancer progression and chemoresistance--implications for IGF-II and IGF-IR-targeted therapy.
PMID: 24599933
Ref: Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance.
PMID: 26475334
Ref: Elevated expression of the IGF2 mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinoma.
PMID: 27391348
Ref: IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness.
PMID: 29604392