Primary Site >> Esophagus Cancer
Gene >> IGF1R
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Ref: A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma. PMID: 21707510 Ref: [Expression of IGF-1R in esophageal squamous cell carcinoma and the effect of its silencing by siRNA on the proliferation of esophageal cancer EC9706 cells in vitro]. PMID: 22325222 |
Ref: Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity. PMID: 22753744 |
Ref: Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer. PMID: 24608110 Ref: Genetic variations in the IGF-IGFR-IGFBP axis confer susceptibility to lung and esophageal cancer. PMID: 24615087 |
Ref: Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming. PMID: 26148236 Ref: Impact of IGF-1, IGF-1R, and IGFBP-3 promoter methylation on the risk and prognosis of esophageal carcinoma. PMID: 26662570 |