Primary Site >> Biliary tract Cancer

Gene >> IGF1

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Ref: Expression of IGF-I, IGF-II, and IGF-IR in gallbladder carcinoma. A systematic analysis including primary and corresponding metastatic tumours.
PMID: 16443739
Ref: Estrogens and insulin-like growth factor 1 modulate neoplastic cell growth in human cholangiocarcinoma.
PMID: 16936263
Ref: Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis.
PMID: 17909206
Ref: Relationship between the GH-IGFs axis and the proliferation of bile duct cancer cell line QBC939 in vitro.
PMID: 18234643
Ref: Serum and bile biomarkers for cholangiocarcinoma.
PMID: 19396965
Ref: Lack of association between risk of biliary tract cancer and circulating IGF (Insulin-like Growth Factor) -I, IGF-II or IGFBP-3 (IGF-binding Protein-3): A nested case-control study in a large scale cohort study in Japan.
PMID: 20553084
Ref: Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance.
PMID: 20066734
Ref: Increased prevalence of gallbladder polyps in acromegaly.
PMID: 21543430
Ref: Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers.
PMID: 22044563
Ref: Suppression of cholangiocarcinoma cell growth by human umbilical cord mesenchymal stem cells: a possible role of Wnt and Akt signaling.
PMID: 23646150
Ref: Modulatory role of garlicin in migration and invasion of intrahepatic cholangiocarcinoma via PI3K/AKT pathway.
PMID: 26823715
Ref: Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells.
PMID: 26470769
Ref: Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway.
PMID: 29110119
Ref: Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway.
PMID: 29170841