Primary Site >> Colorectal Cancer
Gene >> IFNG
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Ref: Effects of human immune interferon on cell viability, (2',5')oligoadenylate synthesis, and polyamine-dependent protein phosphorylation in human colon carcinoma cells in vitro. PMID: 6424936 |
Ref: Differential gamma-interferon response of human colon carcinoma cells: inhibition of proliferation and modulation of immunogenicity as independent effects of gamma-interferon on tumor cell growth. PMID: 3160456 Ref: Recombinant interferon-gamma can induce the expression of HLA-DR and -DC on DR-negative melanoma cells and enhance the expression of HLA-ABC and tumor-associated antigens. PMID: 3918869 Ref: Synergistic effect of human immune interferon and double-stranded RNA against human colon carcinoma cells in vitro. PMID: 3921246 |
Ref: Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma. PMID: 3005411 Ref: Potentiation of the cytocidal effect of human immune interferon by different synthetic double-stranded RNAs in the refractory human colon carcinoma cell line BE. PMID: 3081254 Ref: Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines. PMID: 3089802 Ref: Biologic effects of gamma interferon pre-treatment followed by monoclonal antibody 17-1A administration in patients with gastrointestinal carcinoma. PMID: 3091476 Ref: [Synergistic effect of recombinant human interferon-beta and -gamma on human colon cancer transplanted into nude mice]. PMID: 3096215 |
Ref: Analysis of effector cells in human antibody-dependent cellular cytotoxicity with murine monoclonal antibodies. PMID: 2437198 Ref: Synergistic antitumor effects of tumor necrosis factor and gamma-interferon on human colon carcinoma cell lines. PMID: 3105867 Ref: [Combined effect of human recombinant interferon-beta and interferon-gamma against an experimental model of peritonitis carcinomatosa in nude mice]. PMID: 3109328 Ref: Modulation of cell proliferation by human recombinant interleukin-1 and immune interferon. PMID: 3110477 Ref: Anti-tumor activity of recombinant mouse tumor necrosis factor (TNF) on colon cancer in rats is promoted by recombinant rat interferon gamma; toxicity is reduced by indomethacin. PMID: 3117712 Ref: Antitumor effect of human recombinant interferon-gamma alone and in combination with adriamycin on a human colon cancer cell line (RPMI 4788) in vitro and in nude mice. PMID: 3123441 Ref: Successful treatment of colon cancer in rats with recombinant interferon-gamma. PMID: 3124877 |
Ref: In vivo antitumor activity of multiple injections of recombinant interleukin 2, alone and in combination with three different types of recombinant interferon, on various syngeneic murine tumors. PMID: 2446744 Ref: Interferon-gamma activates the voltage-gated calcium channel in RPMI 4788 cells. PMID: 2455515 Ref: Antibody delivery and effector cell activation in a phase II trial of recombinant gamma-interferon and the murine monoclonal antibody CO17-1A in advanced colorectal carcinoma. PMID: 3128400 Ref: Antiproliferative effects exerted by recombinant human tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human pancreatic tumor cell lines. PMID: 3131759 Ref: Cooperative effect of interferon-gamma and tumor necrosis factor-alpha on the induction of the class II antigen-associated invariant chain expression. PMID: 3144453 Ref: Natural killer, lymphokine-activated killer and interferon-gamma producing activities of peripheral blood- and regional lymph node-mononuclear cells in 23 cases of colorectal cancer. PMID: 3145895 |
Ref: Mechanisms of combined effects of gamma-interferon and 5-fluorouracil on human colon cancers implanted into nude mice. PMID: 2492206 Ref: Phenotypic expression of histocompatibility antigens in human primary tumours and metastases. PMID: 2493352 Ref: Impaired local natural killer cell activity in human colorectal carcinomas. PMID: 2495180 Ref: Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma. PMID: 2499663 Ref: Heterogeneous response of human colon cancer cells to the cytostatic and cytotoxic effects of recombinant human cytokines: interferon-alpha, interferon-gamma, tumor necrosis factor, and interleukin-1. PMID: 2499665 Ref: Recombinant interferon-gamma lacks activity against metastatic colorectal cancer but increases serum levels of CA 19-9. PMID: 2784711 |
Ref: Rat monoclonal antibodies produced against rat colorectal adenocarcinomas define tumor- and colon-associated, auto-immunogenic antigens. PMID: 1692306 Ref: Interaction of gamma interferon and 5-fluorouracil in the H630 human colon carcinoma cell line. PMID: 1697502 Ref: Characterization of the synergistic antiproliferative effects of interferon-gamma and tumor necrosis factor on human colon carcinoma cell lines. PMID: 2111352 Ref: Interferon gamma increases in vitro and in vivo expression of C1 inhibitor. PMID: 2112412 Ref: Anti-proliferative effects of tumor necrosis factor, gamma interferon and 5-fluorouracil on human colorectal carcinoma cell lines. PMID: 2114374 Ref: A phase II trial of recombinant human interferon-gamma and recombinant tumor necrosis factor in patients with advanced gastrointestinal malignancies: results of a trial terminated by excessive toxicity. PMID: 2123922 Ref: In vitro augmentation of macrophage-activating-factor release from peripheral blood cells of cancer patients by a DNA fraction from Mycobacterium bovis BCG. PMID: 2126049 Ref: Humoral and cellular responses of colorectal cancer patients treated with monoclonal antibodies and interferon gamma. PMID: 2126982 Ref: Modulation of interferon receptor expression during combination beta ser-interferon and gamma-interferon treatment of human colon carcinoma cells. PMID: 2136700 Ref: Tumor necrosis factor up-regulates gamma-interferon binding in a human carcinoma cell line. PMID: 2141333 Ref: Effects of combinations of interferon-beta ser and interferon-gamma on interferon-inducible proteins and on the cell cycle. PMID: 2395002 |
Ref: Carcinoembryonic antigen regulation in human colorectal tumor cells by a site-selective cyclic AMP analogue: a comparison with interferon-gamma. PMID: 1645700 Ref: Vectorial release of carcinoembryonic antigen induced by IFN-gamma in human colon cancer cells cultured in serum-free medium. PMID: 1828970 Ref: The effects of gamma-interferon combined with 5-fluorouracil or 5-fluoro-2'-deoxyuridine on proliferation and antigen expression in a panel of human colorectal cancer cell lines. PMID: 1830034 Ref: Halothane potentiates the antitumor activity of gamma-interferon and mimics calmodulin-blocking agents. PMID: 1898840 Ref: Reduced tumorigenicity of murine tumor cells secreting gamma-interferon is due to nonspecific host responses and is unrelated to class I major histocompatibility complex expression. PMID: 1900037 Ref: Interferon enhancement of radioimmunotherapy for colon carcinoma. PMID: 1901760 Ref: Cloning and expression of a cDNA encoding mouse indoleamine 2,3-dioxygenase. PMID: 1937018 Ref: Implications of current therapeutic approaches in colorectal cancer for other gastrointestinal malignancies. PMID: 1992529 |
Ref: Effect of tumor size on the enhancement by gamma interferon of the localization of radiolabeled F(ab')2 fragments of anti-intercellular adhesion molecule-1 monoclonal antibodies in human colon carcinoma cells grafted in nude mice. PMID: 1346588 Ref: Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro. PMID: 1362041 Ref: Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells. PMID: 1477074 Ref: Locally superantigen-activated peritoneal cytolytic T lymphocytes belong to the CD8+ CD45RC- subset and lyse MHC class II+ tumor cells. PMID: 1487309 Ref: [Clinical studies on locoregional immunochemotherapy of peritonitis carcinomatosa]. PMID: 1530341 Ref: Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations. PMID: 1557656 Ref: The expression of class I major histocompatibility antigens by human retinal pigment epithelium in vitro. PMID: 1577302 Ref: Expression of class II major histocompatibility complex molecules correlates with human colon tumor vaccine efficacy. PMID: 1596903 Ref: Spontaneous cytotoxicity of human intraepithelial lymphocytes against epithelial cell tumors. PMID: 1727781 Ref: Identification and characterization of a rat protein (p 105) auto-antigenic in rats bearing a progressive syngeneic colon carcinoma. PMID: 1730526 |
Ref: Amplified expression of intercellular adhesion molecule-1 (ICAM-1) and M(r) 40K protein by DLD-1 colon tumor cells by interferon-gamma. PMID: 8096438 Ref: Interactions between interferon gamma and retinoic acid with transforming growth factor beta in the induction of immune recognition molecules. PMID: 8100485 Ref: The mucosal T cell integrin alpha M290 beta 7 recognizes a ligand on mucosal epithelial cell lines. PMID: 8100775 Ref: Interferon-gamma-induced intercellular adhesion molecule-1: expression on human tumor cells enhances bifunctional antibody-mediated lysis through a lymphocyte function-associated antigen-1 dependent mechanism. PMID: 8104686 Ref: Spontaneous cytotoxicity of intestinal intraepithelial lymphocytes: clues to the mechanism. PMID: 8252812 Ref: Carcinoembryonic antigen mediates in vitro cell aggregation induced by interferon-gamma in a human colon cancer cell line: requirement for active metabolism and intact cytoskeleton. PMID: 8364886 Ref: The human colon cancer cell line CaCo-2 produces secretory components during enterocytic differentiation. PMID: 8375626 Ref: Phorbol myristate acetate-differentiated THP-1 cells display increased levels of MHC class I and class II mRNA and interferon-gamma-inducible tumoricidal activity. PMID: 8396466 Ref: Improved radioimmunotherapeutic efficacy of an anticarcinoma monoclonal antibody (131I-CC49) when given in combination with gamma-interferon. PMID: 8425194 Ref: Growth inhibition of a human colorectal carcinoma cell line by interleukin 1 is associated with enhanced expression of gamma-interferon receptors. PMID: 8425199 Ref: Monocyte-conditioned media possess a novel factor which increases motility of cancer cells. PMID: 8428796 Ref: Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon. PMID: 8453631 Ref: Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma. PMID: 8474431 Ref: Effect of cytokines on the epithelial function of the human colon carcinoma cell line HT29 cl 19A. PMID: 8504961 |
Ref: Tumor cells suppress cytokine-induced nitric-oxide (NO) production in cerebral endothelial cells. PMID: 7525497 Ref: Positive interactions between human interferon and cepharanthin against human cancer cells in vitro and in vivo. PMID: 7527303 Ref: Enhanced killing capacity of human Kupffer cells after activation with human granulocyte/macrophage-colony-stimulating factor and interferon gamma. PMID: 7923248 Ref: Interferon-gamma enhances monoclonal antibody 17-1A-dependent neutrophil cytotoxicity toward colorectal carcinoma cell line SW11-16. PMID: 8137553 Ref: Adoptive cellular therapy of human breast and colorectal tumor targets using ex vivo activated memory T lymphocytes with potentiation by cis-diamminedichloroplatinum(II). PMID: 8159004 Ref: Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium. PMID: 8168998 |
Ref: Cloning and expression of human uridine phosphorylase. PMID: 7488099 Ref: In vitro and in vivo footprint analysis of the promoter of carcinoembryonic antigen in colon carcinoma cells: effects of interferon gamma treatment. PMID: 7641207 Ref: Expansion of mucin-reactive T-helper lymphocytes from patients with colorectal cancer. PMID: 7663570 Ref: Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth. PMID: 7674335 Ref: CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (Gly13-->Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation. PMID: 7728775 Ref: Synergistic effects of IL-6 and IFN-gamma on carcinoembryonic antigen (CEA) and HLA expression by human colorectal carcinoma cells: role for endogenous IFN-beta. PMID: 7780031 Ref: Improved tumor radioimmunodetection using a single-chain Fv and gamma-interferon: potential clinical applications for radioimmunoguided surgery and gamma scanning. PMID: 7796413 Ref: Phase I trial of escalating doses of interleukin-1 beta in combination with a fixed dose of interleukin-2. PMID: 7844609 Ref: Isolation and purification of large quantities of fresh human Kupffer cells, which are cytotoxic against colon carcinoma. PMID: 7875672 Ref: Immunological alterations induced by adjuvant treatment of postoperative colon carcinoma Duke's B or C with levamisole in combination with 5-FU. PMID: 8572636 Ref: Development of immunogenic colorectal cancer cell lines for vaccination: expression of CD80 (B7.1) is not sufficient to restore impaired primary T cell activation in vitro. PMID: 8652275 |
Ref: Expression of a single-chain HLA class I molecule in a human cell line: presentation of exogenous peptide and processed antigen to cytotoxic T lymphocytes. PMID: 8552612 Ref: Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733. PMID: 8621241 Ref: Disregulation in TH1 and TH2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. PMID: 8625361 Ref: Tumor necrosis factor and interferon-gamma augment anticolon antibody- dependent cellular cytotoxicity in ulcerative colitis. PMID: 8683036 Ref: The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-alpha and interleukin-4 predicts improved survival. PMID: 8826937 Ref: Expression of co-stimulatory molecules by tumor cells decreases tumorigenicity but may also reduce systemic antitumor immunity. PMID: 8886848 Ref: Role of interferon regulatory factor-1 in the induction of biliary glycoprotein (cell CAM-1) by interferon-gamma. PMID: 8910434 Ref: Modulation of mdr1 expression by cytokines in human colon carcinoma cells: an approach for reversal of multidrug resistance. PMID: 8912533 Ref: The expression of costimulatory molecules CD80 and CD86 in human carcinoma cell lines: its regulation by interferon gamma and interleukin-10. PMID: 9003466 Ref: Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: enhancement with interferon gamma. PMID: 9003467 |
Ref: Microglial cells induce cytotoxic effects toward colon carcinoma cells: measurement of tumor cytotoxicity with a gamma-glutamyl transpeptidase assay. PMID: 9009156 Ref: Induction of nonspecific cross-reacting antigen mRNA by interferon-gamma and anti-fibronectin receptor antibody in colon cancer cells. PMID: 9085168 Ref: Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. PMID: 9259401 Ref: Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer. PMID: 9435872 Ref: Clinical experience with CD64-directed immunotherapy. An overview. PMID: 9435876 Ref: Biliary glycoprotein is overexpressed in human colon cancer cells with high metastatic potential. PMID: 9834361 Ref: [Activation of the immune system in colorectal carcinoma and its assessment]. PMID: 10103145 |
Ref: Phase I trial of adoptive immunotherapy of cancer patients using monocyte-derived macrophages activated with interferon gamma and lipopolysaccharide. PMID: 9439648 Ref: Transcriptional silencing of perlecan gene expression by interferon-gamma. PMID: 9468523 Ref: Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression. PMID: 9472684 Ref: Selective expression of carcinoembryonic antigen promoter in cancer cell lines: targeting strategy for gene therapy in colorectal cancer. PMID: 9645743 Ref: Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor. PMID: 9653090 Ref: Relation between depression and circulating immune products in patients with advanced colorectal cancer. PMID: 9816354 Ref: Involvement of macrophage migration inhibitory factor (MIF) in the mechanism of tumor cell growth. PMID: 9932108 Ref: Expression of genes that regulate Fas signalling and Fas-mediated apoptosis in colon carcinoma cells. PMID: 10200495 Ref: Anti-Fas antibody-induced apoptosis in human colorectal carcinoma cell lines: role of the p53 gene. PMID: 14646476 |
Ref: Activated natural killer cell tumor retention and cytokine production in colon tumor using a tissue-isolated model. PMID: 10068530 Ref: Early events of hepatic metastasis formation in mice: role of Kupffer and NK-cells in natural and interferon-gamma-stimulated defense. PMID: 10090831 Ref: Expression and regulation by interferon-gamma of the membrane-bound complement regulators CD46 (MCP), CD55 (DAF) and CD59 in gastrointestinal tumours. PMID: 10211099 Ref: Combined antitumour activity of mitomycin C, 5-fluorouracil and interleukin-2 against human colon cancer cells. PMID: 10226560 Ref: Expression of inducible nitric oxide synthase in tumors in relation with their regression induced by lipid A in rats. PMID: 10328229 Ref: Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice. PMID: 10341884 Ref: Modulation of interleukin-18 expression in human colon carcinoma: consequences for tumor immune surveillance. PMID: 10371355 Ref: Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody. PMID: 10391559 Ref: Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes. PMID: 10449520 Ref: Cell surface expression and metabolism of major histocompatibility complex class II invariant chain (CD74) by diverse cell lines. PMID: 10540230 Ref: Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12. PMID: 10608348 |
Ref: Diversion of intestinal flow decreases the numbers of interleukin 4 secreting and interferon gamma secreting T lymphocytes in small bowel mucosa. PMID: 10601053 Ref: Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells. PMID: 10673399 Ref: IL-10 enhances IL-2-induced proliferation and cytotoxicity by human intestinal lymphocytes. PMID: 10691913 Ref: Interleukin-18 in combination with IL-2 enhances natural killer cell activity without inducing large amounts of IFN-gamma in vivo. PMID: 10714558 Ref: Suppression of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure. PMID: 10783318 Ref: Regrowth of 5-fluorouracil-treated human colon cancer cells is prevented by the combination of interferon gamma, indomethacin, and phenylbutyrate. PMID: 10866311 Ref: Regulation of HLA-DR antigen in monocytes from colorectal cancer patients by in vitro treatment with human recombinant interferon-gamma. PMID: 10879996 Ref: Influence of interferon gamma on modulation of Fas expression by human colon carcinoma cells and their subsequent sensitivity to antigen-specific CD8+ cytotoxic T lymphocyte attack. PMID: 10941902 Ref: Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12. PMID: 10961892 Ref: Cytokines secreted by lymphokine-activated killer cells induce endogenous nitric oxide synthesis and apoptosis in DLD-1 colon cancer cells. PMID: 11006006 Ref: A short course of oral aspirin increases IL-18-induced interferon-gamma production in whole blood cultures. PMID: 11022121 Ref: Isolation and molecular characterization of the 5'-upstream region of the human TRAIL gene. PMID: 11027498 Ref: Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis. PMID: 11056003 Ref: [Tumor escape mechanism involving Fas and Fas-L molecules in human colorectal tumors]. PMID: 11173732 Ref: Drug-induced modulation of carcinoembryonic antigen (CEA) expression in neoplastic cells from a patient with rectal cancer. PMID: 11277324 |
Ref: p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. PMID: 11139340 Ref: Effect of inflammatory cytokines and growth factors on tumour cell adhesion to the peritoneum. PMID: 11276014 Ref: Colon epithelial cellular protein induces oral tolerance in the experimental model of colitis by trinitrobenzene sulfonic acid. PMID: 11574820 Ref: Serum factors attenuating the anti-tumor activity of 5-fluorouracil. PMID: 11603002 Ref: Expression of WNT14 and WNT14B mRNAs in human cancer, up-regulation of WNT14 by IFNgamma and up-regulation of WNT14B by beta-estradiol. PMID: 11713592 Ref: Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells. PMID: 11911240 |
Ref: Decreased production of interleukin-12 and type 2 immune responses are marked in cachectic patients with colorectal and gastric cancer. PMID: 11907352 Ref: Pharmacological modulation of carcinoembryonic antigen in human cancer cells: studies with staurosporine. PMID: 12013504 Ref: Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism. PMID: 12058282 Ref: Interferon-alpha (Intron A) upregulates urokinase-type plasminogen activator receptor gene expression. PMID: 12070711 Ref: Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. PMID: 12087451 Ref: Gamma interferon down-regulates Fer and induces its association with inactive Stat3 in colon carcinoma cells. PMID: 12118379 Ref: Modulation of the Fas signaling pathway by IFN-gamma in therapy of colon cancer: phase I trial and correlative studies of IFN-gamma, 5-fluorouracil, and leucovorin. PMID: 12171874 Ref: Hypoxia upregulates Bcl-2 expression and suppresses interferon-gamma induced antiangiogenic activity in human tumor derived endothelial cells. PMID: 12173346 Ref: Nitrosation and nitration of 2-amino-3-methylimidazo[4,5-f]quinoline by reactive nitrogen oxygen species. PMID: 12184790 Ref: Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8(+) T-cell epitope, which mediates tumor killing in CEA transgenic mice. PMID: 12208761 Ref: Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells. PMID: 12297499 Ref: Adjuvant effect of a Flt3 ligand (FL) gene-transduced xenogeneic cell line in a murine colon cancer model. PMID: 12443727 Ref: Generation of human interferon gamma and tumor Necrosis factor alpha chimeric TNT-3 fusion proteins. PMID: 12573106 |
Ref: Autologous and MHC class I-negative allogeneic tumor cells secreting IL-12 together cure disseminated A20 lymphoma. PMID: 12393660 Ref: Impaired expression of proteasome subunits and human leukocyte antigens class I in human colon cancer cells. PMID: 12519221 Ref: Vitamin E supplementation does not alter azoxymethane-induced colonic aberrant crypt foci formation in young or old mice. PMID: 12566495 Ref: Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts. PMID: 12637939 Ref: Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. PMID: 12702049 Ref: Induction of systemic immunity by expression of interleukin-23 in murine colon carcinoma cells. PMID: 12767068 Ref: Phorbol myristate acetate and Bryostatin 1 rescue IFN-gamma inducibility of MHC class II molecules in LS1034 colorectal carcinoma cell line. PMID: 12787470 Ref: Frequent death-associated protein-kinase promoter hypermethylation in brain metastases of solid tumors. PMID: 12792765 Ref: Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-gamma. PMID: 12794166 Ref: Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines. PMID: 12865931 Ref: A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8+ T cells. PMID: 12874012 Ref: Synergistic effect of a granulocyte-macrophage colony-stimulating factor-transduced tumor vaccine and systemic interleukin-2 in the treatment of murine colorectal cancer hepatic metastases. PMID: 12900373 Ref: Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression. PMID: 12972432 Ref: Glutamine prevents cytokine-induced apoptosis in human colonic epithelial cells. PMID: 14519785 Ref: Antitumor effects of interleukin-18 gene-modified hepatocyte cell line on implanted liver carcinoma. PMID: 14570604 Ref: Locoregional immunotherapy of malignant effusion from colorectal cancer using the streptococcal preparation OK-432 plus interleukin-2: induction of autologous tumor-reactive CD4+ Th1 killer lymphocytes. PMID: 14612896 Ref: Treatment of human solid malignancies with autologous activated lymphocytes and cimetidine: a phase II trial of the cancer biotherapy research group. PMID: 14629821 Ref: Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence. PMID: 14636419 |
Ref: Angiopoietin decoy secreted at tumor site impairs tumor growth and metastases by inducing local inflammation and altering neoangiogenesis. PMID: 14985859 Ref: Nitric oxide differentially regulates pro- and anti-angiogenic markers in DLD-1 colon carcinoma cells. PMID: 15063730 Ref: In vitro antitumor immune response induced by fusion of dendritic cells and colon cancer cells. PMID: 15069718 Ref: Interferon-gamma and TRAIL in human breast tumor cells. PMID: 15110183 Ref: LIGHT sensitizes IFN-gamma-mediated apoptosis of HT-29 human carcinoma cells through both death receptor and mitochondria pathways. PMID: 15115612 Ref: [Dendritomas plays an important role in the activation of anti-tumor immune responses]. PMID: 15200907 Ref: Nitric oxide from rat liver sinusoidal endothelial cells induces apoptosis in IFN gamma-sensitized CC531s colon carcinoma cells. PMID: 15246201 Ref: IL-6-induced survival of colorectal carcinoma cells is inhibited by butyrate through down-regulation of the IL-6 receptor. PMID: 15284182 Ref: Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients. PMID: 15328177 Ref: Cytotoxic T-cell immunity against telomerase reverse transcriptase in colorectal cancer patients. PMID: 15375515 Ref: The effect of Edrecolomab (Mo17-1A) or fluorouracil-based chemotherapy on specific immune parameters in patients with colorectal cancer. A comparative study. PMID: 15713997 Ref: Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. PMID: 15790545 |
Ref: Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor. PMID: 15713431 Ref: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma. PMID: 15856455 Ref: Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer. PMID: 15914572 Ref: Therapeutic potential of Kupffer cells in prevention of liver metastases outgrowth. PMID: 16164033 Ref: Cellular differentiation-induced attenuation of LPS response in HT-29 cells is related to the down-regulation of TLR4 expression. PMID: 16202385 Ref: Effector memory T cells, early metastasis, and survival in colorectal cancer. PMID: 16371631 |
Ref: A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells. PMID: 16188919 Ref: Tumor necrosis factor-alpha and interferon-gamma increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine. PMID: 16328452 Ref: Predominant T helper type 2-inflammatory responses promote murine colon cancers. PMID: 16331625 Ref: Strong HLA-DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c-myc suppression by interferon-gamma in situ. PMID: 16367922 Ref: Preoperative oral immune-enhancing nutritional supplementation corrects TH1/TH2 imbalance in patients undergoing elective surgery for colorectal cancer. PMID: 16421661 Ref: Immunomodulation with low dose levamisole in patients with colonic polyps. PMID: 16458451 Ref: Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4. PMID: 16630022 Ref: Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer. PMID: 16641897 Ref: Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases. PMID: 16773688 Ref: Effect of milk fermented with a Lactobacillus helveticus R389(+) proteolytic strain on the immune system and on the growth of 4T1 breast cancer cells in mice. PMID: 16831211 Ref: ICAM-1 inhibits the homocluster formation of MHC-I in colon carcinoma cells. PMID: 16844085 Ref: Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen. PMID: 16895556 Ref: Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation. PMID: 16928387 |
Ref: STAT1-independent inhibition of cyclooxygenase-2 expression by IFNgamma; a common pathway of IFNgamma-mediated gene repression but not gene activation. PMID: 17016440 Ref: Xenovaccinotherapy for colorectal cancer. PMID: 17258887 Ref: Does impaired TH1/TH2 balance cause postoperative infectious complications in colorectal cancer surgery? PMID: 17292403 Ref: Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients. PMID: 17349080 Ref: [Effect of tumor burden on differentiation of T lymphocytes in the peripheral blood of patients with colorectal cancer]. PMID: 17403305 Ref: Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. PMID: 17457211 Ref: [Effects of two different antigen-loading methods on the activity of dendritic cell vaccine for colorectal carcinoma cell inhibition in vitro]. PMID: 17545041 Ref: Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice. PMID: 17631136 Ref: Tumor doubling time and local immune response to hepatic metastases from colorectal cancer. PMID: 17654526 Ref: Adenoviral B7-H3 therapy induces tumor specific immune responses and reduces secondary metastasis in a murine model of colon cancer. PMID: 17671729 Ref: Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides. PMID: 17893568 Ref: How relevant are cytokines in colorectal cancer wasting? PMID: 18032977 |
Ref: Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand. PMID: 18284469 Ref: Metinel node--the first lymph node draining a metastasis--contains tumor-reactive lymphocytes. PMID: 18299934 Ref: The specific immune response to tumor antigen CP1 and its correlation with improved survival in colon cancer patients. PMID: 18395081 Ref: Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo. PMID: 18603231 Ref: CpG methylation of the IFNG gene as a mechanism to induce immunosuppression [correction of immunosupression] in tumor-infiltrating lymphocytes. PMID: 18684979 Ref: Anti-proliferative effect of interferon-gamma is enhanced by iron chelation in colon cancer cell lines in vitro. PMID: 18795672 Ref: Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. PMID: 18929641 |
Ref: IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. PMID: 18418598 Ref: Impact of surgery on immunologic function: comparison between minimally invasive techniques and conventional laparotomy for surgical resection of colorectal tumors. PMID: 18639228 Ref: Contribution of intestinal epithelial cells to innate immunity of the human gut--studies on polarized monolayers of colon carcinoma cells. PMID: 19170965 Ref: Activation of tumor-specific T lymphocytes after laser-induced thermotherapy in patients with colorectal liver metastases. PMID: 19184001 Ref: EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion. PMID: 19188665 Ref: Substantially reduced expression of PIAS1 is associated with colon cancer development. PMID: 19288270 Ref: Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy. PMID: 19401694 Ref: Cyclophosphamide unmasks an antimetastatic effect of local tumor cryoablation. PMID: 19407102 Ref: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide--interference with interferon-gamma-STAT1-mediated killing. PMID: 19476491 Ref: Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer. PMID: 19816950 |
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