Primary Site >> Colorectal Cancer
Gene >> IFIH1
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Ref: PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo. PMID: 25898986 Ref: DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts. PMID: 26317465 |
Ref: Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis. PMID: 28224203 Ref: The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy. PMID: 28917654 |
Ref: The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer. PMID: 28940253 Ref: Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production. PMID: 29367762 Ref: Fascin1 suppresses RIG-I-like receptor signaling and interferon-beta production by associating with IkappaB kinase (IKK) in colon cancer. PMID: 29496994 |