Primary Site >> Pancreatic Cancer
Gene >> IFI27
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Ref: Vitamin D analogues up-regulate p21 and p27 during growth inhibition of pancreatic cancer cell lines. PMID: 9328147 |
Ref: Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells. PMID: 9516449 |
Ref: A clinicopathologic and immunohistochemical study of 22 intraductal papillary mucinous neoplasms of the pancreas, with a review of the literature. PMID: 10349991 |
Ref: The proteasome controls the expression of a proliferation-associated nuclear antigen Ki-67. PMID: 10653979 Ref: An immunohistochemical analysis of p27 expression in human pancreatic carcinomas. PMID: 11039465 Ref: Prognostic Significance of p27, Ki-67, and Topoisomerase lla Expression in Clinically Nonfunctioning Pancreatic Endocrine Tumors. PMID: 12114695 |
Ref: Deregulated expression of cell cycle-associated proteins in solid pseudopapillary tumor of the pancreas. PMID: 11235905 Ref: The epidermal growth factor receptor as a target for cancer therapy. PMID: 11350723 Ref: Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines. PMID: 11522750 |
Ref: Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. PMID: 12010891 Ref: Fas and Fas ligand expression in pancreatic adenocarcinoma. PMID: 12370548 |
Ref: MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac. PMID: 14576498 Ref: Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines. PMID: 14586404 |
Ref: Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3. PMID: 14742320 Ref: The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts. PMID: 14749476 Ref: Suppression of human pancreatic cancer cell proliferation by AGN194204, an RXR-selective retinoid. PMID: 14976133 Ref: Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines. PMID: 15084985 Ref: The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity. PMID: 15309028 Ref: Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins. PMID: 15345676 |
Ref: Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. PMID: 15811853 Ref: A novel retinoid-related molecule inhibits pancreatic cancer cell proliferation by a retinoid receptor independent mechanism via suppression of cell cycle regulatory protein function and induction of caspase-associated apoptosis. PMID: 15856029 Ref: Neutral lipid isolated from endosperm of Job's tears inhibits the growth of pancreatic cancer cells via apoptosis, G2/M arrest, and regulation of gene expression. PMID: 15955213 Ref: Expression of transforming growth factor-beta-1 and p27Kip1 in pancreatic adenocarcinomas: relation with cell-cycle-associated proteins and clinicopathologic characteristics. PMID: 16086840 Ref: Molecular prognostic markers in pancreatic cancer: a systematic review. PMID: 16146690 Ref: Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma. PMID: 16170025 |
Ref: Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells. PMID: 16546962 Ref: Cyclin E expression and outcome in pancreatic ductal adenocarcinoma. PMID: 17035403 |
Ref: Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells. PMID: 17138864 Ref: Solid pseudopapillary neoplasms of the pancreas show an interruption of the Wnt-signaling pathway and express gene products of 11q. PMID: 17632456 Ref: Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. PMID: 17804744 Ref: Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth. PMID: 17875936 |
Ref: Curcumin as "Curecumin": from kitchen to clinic. PMID: 17900536 Ref: 19-nor-1 alpha,25-dihydroxyvitamin D2 (paricalcitol) inhibits the proliferation of human pancreatic cancer cells in vitro and in vivo. PMID: 18094617 Ref: Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. PMID: 18559508 Ref: PDX-1 acts as a potential molecular target for treatment of human pancreatic cancer. PMID: 18665085 Ref: Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. PMID: 18694622 |
Ref: Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas. PMID: 18957496 Ref: Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. PMID: 19020940 Ref: Induction of apoptosis and nonsteroidal anti-inflammatory drug-activated gene 1 in pancreatic cancer cells by a glycyrrhetinic acid derivative. PMID: 19125423 Ref: Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer. PMID: 19421011 Ref: The nonsteroidal anti-inflammatory drug tolfenamic acid inhibits BT474 and SKBR3 breast cancer cell and tumor growth by repressing erbB2 expression. PMID: 19435870 Ref: Vitamin D for the prevention and treatment of pancreatic cancer. PMID: 19610135 Ref: Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression. PMID: 19672266 Ref: Antisense inhibition of microRNA-21 or -221 arrests cell cycle, induces apoptosis, and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma. PMID: 19730150 |
Ref: Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. PMID: 19910837 Ref: Blocking angiotensin II Type 1 receptor triggers apoptotic cell death in human pancreatic cancer cells. PMID: 20118823 Ref: Differential cell cycle and proliferation marker expression in ductal pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia (PanIN). PMID: 20350215 Ref: Gankyrin promotes the proliferation of human pancreatic cancer. PMID: 20483533 Ref: Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer. PMID: 20642839 Ref: KLF4alpha up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer. PMID: 20727893 |
Ref: CacyBP/SIP protein promotes proliferation and G1/S transition of human pancreatic cancer cells. PMID: 21268134 Ref: Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway. PMID: 21350002 Ref: Dysregulation of the cell cycle and chromosomal imbalances in juxtaglomerular cell tumors - a comparative study with endocrine tumors of the pancreas. PMID: 21482036 Ref: Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer. PMID: 21644238 Ref: Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells. PMID: 21720559 Ref: Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors. PMID: 21980390 Ref: Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-I. PMID: 22028818 |
Ref: The PPAR-gamma agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-beta treated pancreatic cancer cells. PMID: 21871555 Ref: Effect of a combination of S-1 and gemcitabine on cell cycle regulation in pancreatic cancer cell lines. PMID: 22334000 Ref: The detection of EBP50 expression using quantum dot immunohistochemistry in pancreatic cancer tissue and down-regulated EBP50 effect on PC-2 cells. PMID: 22622406 Ref: Gatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53. PMID: 23133524 |
Ref: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. PMID: 22971992 Ref: Evaluation of the potential therapeutic role of a new generation of vitamin D analog, MART-10, in human pancreatic cancer cells in vitro and in vivo. PMID: 23549173 |
Ref: SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers. PMID: 24552806 Ref: Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses vasculogenic mimicry and proliferation of highly aggressive pancreatic cancer PaTu8988 cells. PMID: 24886166 Ref: Secreted protein acidic and rich in cysteine inhibits the growth of human pancreatic cancer cells with G1 arrest induction. PMID: 25027401 Ref: Histone deacetylase 3 promotes pancreatic cancer cell proliferation, invasion and increases drug-resistance through histone modification of P27, P53 and Bax. PMID: 25070540 Ref: IL-35 promotes pancreas cancer growth through enhancement of proliferation and inhibition of apoptosis: evidence for a role as an autocrine growth factor. PMID: 25073578 Ref: Cyr61 promotes growth of pancreatic carcinoma via nuclear exclusion of p27. PMID: 25104090 |
Ref: The Interplay Between miR-148a and DNMT1 Might be Exploited for Pancreatic Cancer Therapy. PMID: 25950085 Ref: Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells. PMID: 25955843 Ref: Application of chemokine receptor antagonist with stents reduces local inflammation and suppresses cancer growth. PMID: 26044561 Ref: Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway. PMID: 26166196 Ref: Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation. PMID: 26260159 Ref: MicroRNA-222 Controls Human Pancreatic Cancer Cell Line Capan-2 Proliferation by P57 Targeting. PMID: 26535064 |
Ref: KLF8 knockdown triggered growth inhibition and induced cell phase arrest in human pancreatic cancer cells. PMID: 26995652 Ref: Bufalin inhibits pancreatic cancer by inducing cell cycle arrest via the c-Myc/NF-kappaB pathway. PMID: 27686271 |
Ref: Progesterone inhibits proliferation and modulates expression of proliferation-Related genes in classical progesterone receptor-negative human BxPC3 pancreatic adenocarcinoma cells. PMID: 27449817 Ref: MiR-216a decreases MALAT1 expression, induces G2/M arrest and apoptosis in pancreatic cancer cells. PMID: 28034748 Ref: Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells. PMID: 28841232 Ref: The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators. PMID: 29029505 Ref: The lncRNA XIST interacts with miR-140/miR-124/iASPP axis to promote pancreatic carcinoma growth. PMID: 29371940 |
Ref: Mitochondrial glutamine metabolism via GOT2 supports pancreatic cancer growth through senescence inhibition. PMID: 29352139 Ref: miR448 targets Rab2B and is pivotal in the suppression of pancreatic cancer. PMID: 30015954 Ref: Manzamine A Exerts Anticancer Activity against Human Colorectal Cancer Cells. PMID: 30060617 Ref: WAVE2 is associated with poor prognosis in pancreatic cancers and promotes cell motility and invasiveness via binding to ACTN4. PMID: 30353690 Ref: Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1. PMID: 30374056 |