Primary Site >> Colorectal Cancer
Gene >> IFI27
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. PMID: 9018245 Ref: High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. PMID: 9177226 Ref: Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. PMID: 9202067 Ref: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. PMID: 9310133 |
Ref: Low p27 expression predicts poor disease-free survival in patients with prostate cancer. PMID: 9474188 Ref: Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. PMID: 9736017 |
Ref: Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a). PMID: 10207115 Ref: NA22598, a novel antitumor compound, reduces cyclin D1 levels, arrests cell cycle at G1 phase, and inhibits anchorage-independent growth of human tumor cells. PMID: 10366423 Ref: Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization. PMID: 10398135 Ref: p27 modulates cell cycle progression and chemosensitivity in human malignant glioma. PMID: 10441521 Ref: Variable genetic alterations and survival in head and neck cancer. PMID: 10488977 Ref: Abnormalities in the expression of cell cycle-related proteins in tumors of the small bowel. PMID: 10613343 Ref: beta-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells. PMID: 10656873 Ref: p27(kipl) protein expression: an independent prognostic factor in rectal carcinoma stages I-III. PMID: 23574593 |
Ref: Expression of cell cycle control proteins in primary colorectal tumors does not always predict expression in lymph node metastases. PMID: 10741741 Ref: Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. PMID: 10783304 Ref: Down-regulation of p27 is a significant predictor of poor overall survival and may facilitate metastasis in colorectal carcinomas. PMID: 10861495 Ref: Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production. PMID: 10873106 Ref: Augmentation of antitumor activity of 5-fluorouracil by interferon alpha is associated with up-regulation of p27Kip1 in human hepatocellular carcinoma cells. PMID: 10914738 Ref: Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen Colorectal Initiative. PMID: 10964085 Ref: Altered expression of p53 and p27 proteins, alone or combined, as a predictor of metastatic potential in early invasive carcinoma of colon and rectum--a comparative clinicopathologic and molecular analysis. PMID: 11059565 Ref: Human colorectal cancers with an intact p16/cyclin D1/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters. PMID: 11106567 Ref: Colorectal carcinomas with high microsatellite instability: defining a distinct immunologic and molecular entity with respect to prognostic markers. PMID: 11150376 |
Ref: Butyrate-induced differentiation of Caco-2 cells occurs independently from p27. PMID: 11181044 Ref: Effect of the nonsteroidal anti-inflammatory drug indomethacin on proliferation and apoptosis of colon carcinoma cells. PMID: 11260862 Ref: Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody. PMID: 11313939 Ref: Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. PMID: 11325813 Ref: The epidermal growth factor receptor as a target for cancer therapy. PMID: 11350723 Ref: Loss of p27 expression predicts poor prognosis in patients with Dukes' B stage or proximal colorectal cancer. PMID: 11408921 Ref: Activation of cyclin E-dependent kinase activity in colorectal cancer. PMID: 11680595 Ref: Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells. PMID: 11713597 |
Ref: 5-FU improves p27-related poor prognosis in patients with Astler-Coller B2-C colorectal carcinoma. PMID: 11748451 Ref: Induction of cell cycle arrest and apoptosis in human colon adenocarcinoma cell lines by beta-carotene through down-regulation of cyclin A and Bcl-2 family proteins. PMID: 11756218 Ref: Molecular staging of colorectal cancer in African-American and Caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 AND p27(kip-1). PMID: 11802199 Ref: Primary colorectal tumour is not an accurate predictor of thymidylate synthase in lymph node metastasis. PMID: 11836585 Ref: Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. PMID: 11884591 Ref: Analysis of key cell-cycle checkpoint proteins in colorectal tumours. PMID: 11920733 Ref: Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest. PMID: 11922774 Ref: p21, p27, cyclin D1, and p53 in rectal cancer: immunohistology with prognostic significance? PMID: 12018448 Ref: Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells. PMID: 12055189 Ref: The prognostic value of invariant chain (Ii) and Her-2/neu expression in curatively resected colorectal cancer. PMID: 12074327 Ref: Resveratrol enhances the differentiation induced by butyrate in caco-2 colon cancer cells. PMID: 12097697 Ref: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1. PMID: 12124333 Ref: Fighting colorectal cancer: molecular epidemiology differences among Ashkenazi and Sephardic Jews and Palestinians. PMID: 12196377 Ref: Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. PMID: 12244568 Ref: Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells. PMID: 12376477 Ref: Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms. PMID: 12395374 Ref: Prognostic significance of p21 and p27 protein, apoptosis, clinical and histologic factors in rectal cancer without lymph node metastases. PMID: 12403937 Ref: Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. PMID: 12404222 Ref: Tissue microarray molecular profiling of early, node-negative adenocarcinoma of the rectum: a comprehensive analysis. PMID: 12473598 Ref: [Relationship between expression of p27 and DNA ploidy in colorectal carcinoma]. PMID: 12500398 Ref: [Relationship between p27 expression and prognosis of colorectal carcinoma]. PMID: 12508646 |
Ref: Rapid turnover of cell-cycle regulators found in Mirk/dyrk1B transfectants. PMID: 12455049 Ref: Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. PMID: 12615711 Ref: In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest. PMID: 12794767 Ref: Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells. PMID: 12810668 Ref: Poor prognosis of colorectal cancer in patients over 80 years old is associated with down-regulation of tumor suppressor genes. PMID: 12811209 Ref: [Expression of P27 protein and cyclin E in colon cancer]. PMID: 14558959 Ref: Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. PMID: 14608092 Ref: Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. PMID: 14614451 |
Ref: N-methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA. PMID: 14728717 Ref: Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. PMID: 15041464 Ref: Immunohistochemical expression of cyclin D1, cyclin E, p21/waf1 and p27/kip1 in inflammatory bowel disease: correlation with other cell-cycle-related proteins (Rb, p53, ki-67 and PCNA) and clinicopathological features. PMID: 15060836 Ref: Comparative analysis of cell adhesion molecules, cell cycle regulatory proteins, mismatch repair genes, cyclooxygenase-2, and DPC4 in carcinomas arising in inflammatory bowel disease and sporadic colon cancer. PMID: 15069531 Ref: Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK. PMID: 15122344 Ref: Determination of molecular marker expression can predict clinical outcome in colon carcinomas. PMID: 15161706 Ref: Thermal enhancement of oxaliplatin-induced inhibition of cell proliferation and cell cycle progression in human carcinoma cell lines. PMID: 15204521 Ref: [The construction of yeast two-hybrid method in the protein-interactions and its significance in hepatic metastasis of colorectal carcinoma]. PMID: 15329257 Ref: Expression profiling of colorectal carcinomas using tissue microarrays: cell cycle regulatory proteins p21, p27, and p53 as immunohistochemical prognostic markers in univariate and multivariate analysis. PMID: 15354735 Ref: Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. PMID: 15453709 Ref: Mad2 and p27 expression profiles in colorectal cancer and its clinical significance. PMID: 15457580 Ref: Microsatellite status and cell cycle associated markers in rectal cancer patients undergoing a combined regimen of 5-FU and CPT-11 chemotherapy and radiotherapy. PMID: 15510606 Ref: Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome. PMID: 15525823 Ref: Prognostic value of p27, p53, and vascular endothelial growth factor in Dukes A and B colon cancer patients undergoing potentially curative surgery. PMID: 15622584 Ref: Thymidylate synthase expression, p53, bcl-2, Ki-67 and p27 in colorectal cancer: relationships with tumor recurrence and survival. PMID: 15627889 Ref: Cyclin E, p27 and mutant p53 do not predict the prognosis in AJCC stage II colorectal carcinomas. PMID: 15665575 |
Ref: Characterization of the N-methoxyindole-3-carbinol (NI3C)--induced cell cycle arrest in human colon cancer cell lines. PMID: 15483186 Ref: Calcium sensing receptor in human colon carcinoma: interaction with Ca(2+) and 1,25-dihydroxyvitamin D(3). PMID: 15695391 Ref: The clinical significance of p53, p21, and p27 expressions in rectal carcinoma. PMID: 15722792 Ref: Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways. PMID: 15919146 Ref: Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy. PMID: 15929791 Ref: Adjuvant treatment of colon cancer. PMID: 15933474 Ref: Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. PMID: 16002406 Ref: Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells. PMID: 16112579 Ref: Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer. PMID: 16166444 Ref: Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. PMID: 16192633 Ref: Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/p21 expression in human colon cancer cells. PMID: 16224795 Ref: Escherichia coli verotoxin 1 mediates apoptosis in human HCT116 colon cancer cells by inducing overexpression of the GADD family of genes and S phase arrest. PMID: 16297916 |
Ref: Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations. PMID: 16108056 Ref: Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines. PMID: 16170347 Ref: Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells. PMID: 16344270 Ref: Truncated APC is required for cell proliferation and DNA replication. PMID: 16450383 Ref: Profiling markers of prognosis in colorectal cancer. PMID: 16489072 Ref: The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer. PMID: 16525652 Ref: Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway. PMID: 16574813 Ref: Prognostic significance of epidermal growth factor receptor expression in colon cancer patients undergoing curative surgery. PMID: 16614884 Ref: Over-expressed estrogen receptor-alpha up-regulates hTNF-alpha gene expression and down-regulates beta-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells. PMID: 16628468 Ref: Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. PMID: 16648559 Ref: Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner. PMID: 16830793 Ref: Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer. PMID: 17007015 Ref: Loss of p27 expression and microsatellite instability in sporadic colorectal cancer. PMID: 17123889 Ref: Effect of ligand troglitazone on peroxisome proliferator-activated receptor gamma expression and cellular growth in human colon cancer cells. PMID: 17143939 Ref: Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis. PMID: 17178856 Ref: p53 and p27 as predictors of clinical outcome for rectal-cancer patients receiving neoadjuvant therapy. PMID: 17360176 |
Ref: Distinct molecular patterns based on proximal and distal sporadic colorectal cancer: arguments for different mechanisms in the tumorigenesis. PMID: 17021745 Ref: Different matrix micro-environments in colon cancer and diverticular disease. PMID: 17021746 Ref: Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP. PMID: 17086168 Ref: Prognostic value of cell cycle and apoptosis regulatory proteins in mismatch repair-proficient colorectal cancer: a tissue microarray-based approach. PMID: 17145638 Ref: Domain 5 of kininogen inhibits proliferation of human colon cancer cell line (HCT-116) by interfering with G1/S in the cell cycle. PMID: 17155949 Ref: Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype. PMID: 17239930 Ref: Epistatic relationship between the cancer susceptibility genes CHEK2 and p27. PMID: 17372254 Ref: Sulindac treatment in hereditary non-polyposis colorectal cancer. PMID: 17434727 Ref: 18F-FDG PET scanning correlates with tissue markers of poor prognosis and predicts mortality for patients after liver resection for colorectal metastases. PMID: 17475966 Ref: p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation. PMID: 17486059 Ref: The growth-inhibitory effects of tomatoes digested in vitro in colon adenocarcinoma cells occur through down regulation of cyclin D1, Bcl-2 and Bcl-xL. PMID: 17490506 Ref: Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase. PMID: 17545604 Ref: Identification of JTP-70902, a p15(INK4b)-inductive compound, as a novel MEK1/2 inhibitor. PMID: 17784872 Ref: Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. PMID: 17950073 Ref: Bilirubin inhibits tumor cell growth via activation of ERK. PMID: 18073533 |
Ref: Curcumin as "Curecumin": from kitchen to clinic. PMID: 17900536 Ref: BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. PMID: 18098337 Ref: Expression of P53, P27 and KI-67 in colorectal cancer patients of various ethnic origins: clinical and tissue microarray based analysis. PMID: 18286523 Ref: A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization. PMID: 18305109 Ref: Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. PMID: 18320073 Ref: Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. PMID: 18377871 Ref: p27 Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells. PMID: 18408738 Ref: Crude extracts of Solanum lyratum induced cytotoxicity and apoptosis in a human colon adenocarcinoma cell line (colo 205). PMID: 18507053 Ref: Lycopene inhibits growth of human colon cancer cells via suppression of the Akt signaling pathway. PMID: 18537129 Ref: RHAMM, p21 combined phenotype identifies microsatellite instability-high colorectal cancers with a highly adverse prognosis. PMID: 18559599 Ref: Activation of protein kinase G Increases the expression of p21CIP1, p27KIP1, and histidine triad protein 1 through Sp1. PMID: 18593937 Ref: Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype. PMID: 18983468 Ref: [Hic-5/ARA55 inhibits the growth of Lovo cells by up-regulating the expression of P27]. PMID: 19035221 Ref: Anti-cancer effects of xanthones from pericarps of mangosteen. PMID: 19325754 |
Ref: Impact of p27mt gene on transplantation model of human colorectal cancer in nude mice. PMID: 19140239 Ref: Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene expression in breast cancer and normal mammary epithelial cells. PMID: 19144873 Ref: Inhibition of STAT5 induces G1 cell cycle arrest and reduces tumor cell invasion in human colorectal cancer cells. PMID: 19290007 Ref: Curcumin synergizes the growth inhibitory properties of Indian toad (Bufo melanostictus Schneider) skin-derived factor (BM-ANF1) in HCT-116 colon cancer cells. PMID: 19331178 Ref: Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. PMID: 19423215 Ref: A cohort study of p27 localization in colon cancer, body mass index, and patient survival. PMID: 19505918 Ref: Radiosensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate. PMID: 19507186 Ref: A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis. PMID: 19513025 Ref: Effect of p27mt gene on apoptosis of the colorectal cancer cell line Lovo. PMID: 19522032 Ref: A cohort study of cyclin D1 expression and prognosis in 602 colon cancer cases. PMID: 19549773 Ref: E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. PMID: 19562678 Ref: Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells. PMID: 19602591 Ref: A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers. PMID: 19686742 Ref: Low p27 expression predicts early relapse and death in postmenopausal hormone receptor-positive breast cancer patients receiving adjuvant tamoxifen therapy. PMID: 19723645 Ref: Interaction of molecular markers and physical activity on mortality in patients with colon cancer. PMID: 19723652 Ref: Influence of paeonol on expression of COX-2 and p27 in HT-29 cells. PMID: 19764092 Ref: Depletion of PI3K p85alpha induces cell cycle arrest and apoptosis in colorectal cancer cells. PMID: 19885597 Ref: Inhibitory effects of the ethanol extract of Gleditsia sinensis thorns on human colon cancer HCT116 cells in vitro and in vivo. PMID: 19885606 Ref: Xanthorrhizol, a natural sesquiterpenoid, induces apoptosis and growth arrest in HCT116 human colon cancer cells. PMID: 19926935 |
Ref: RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer. PMID: 19686745 Ref: CDK8 expression in 470 colorectal cancers in relation to beta-catenin activation, other molecular alterations and patient survival. PMID: 19790197 Ref: CD133 expression predicts for non-response to chemotherapy in colorectal cancer. PMID: 20081809 Ref: Tissue microarray constructs to predict a response to chemoradiation in rectal cancer. PMID: 20227932 Ref: Gankyrin promotes the proliferation of human pancreatic cancer. PMID: 20483533 Ref: [Hath1 gene transfer inhibits the proliferation of colonic cancer cells in vitro]. PMID: 20501407 Ref: Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways. PMID: 20504360 Ref: miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation. PMID: 20647341 Ref: Significance of p27 as potential biomarker for intracellular oxidative status. PMID: 21103079 Ref: Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT116 Human Colon Cancer Cells; Involvement of Reactive Oxygen Species. PMID: 21311680 |
Ref: Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body of Antrodia camphorate. PMID: 19293251 Ref: Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review. PMID: 20473920 Ref: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. PMID: 21286718 Ref: Parafibromin expression is an independent prognostic factor for colorectal carcinomas. PMID: 21315421 Ref: Modulation of liver X receptor signaling as a prevention and therapy for colon cancer. PMID: 21333456 Ref: Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells. PMID: 21462330 Ref: Folate receptor-alpha expression in resectable hepatic colorectal cancer metastases: patterns and significance. PMID: 21572402 Ref: Aspirin reduces the apoptotic effect of etoposide via Akt activation and up-regulation of p21(cip). PMID: 21617849 Ref: Thermostable direct hemolysin downregulates human colon carcinoma cell proliferation with the involvement of E-cadherin, and beta-catenin/Tcf-4 signaling. PMID: 21625458 Ref: Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF-kappaB nucleus translocation in macrophages and induce apoptosis by activating caspases-8 and -3 in human colon cancer cells. PMID: 21656672 Ref: Study of the Anti-Proliferative Activity of 5-Substituted 4,7-Dimethoxy-1,3-Benzodioxole Derivatives of SY-1 from Antrodia camphorata on Human COLO 205 Colon Cancer Cells. PMID: 21785624 Ref: Pretreatment CD133 and cyclooxygenase-2 expression as the predictive markers of the pathological effect of chemoradiotherapy in rectal cancer patients. PMID: 21825889 Ref: Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth. PMID: 21847367 Ref: Cell cycle arrest and apoptosis induced by methyl 3,5-dicaffeoyl quinate in human colon cancer cells: Involvement of the PI3K/Akt and MAP kinase pathways. PMID: 21872580 Ref: Valproate inhibits colon cancer growth through cell cycle modification in vivo and in vitro. PMID: 22977502 |
Ref: Expression of cell cycle regulators p21 and p27 as predictors of disease outcome in colorectal carcinoma. PMID: 21637966 Ref: The use of molecular markers as a method to predict the response to neoadjuvant therapy for advanced stage rectal adenocarcinoma. PMID: 21689364 Ref: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells. PMID: 21901254 Ref: B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells. PMID: 22008852 Ref: Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells. PMID: 22307336 Ref: Cell cycle proteins predict recurrence in stage II and III colon cancer. PMID: 22311118 Ref: In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway. PMID: 22429157 Ref: Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression. PMID: 22511578 Ref: MicroRNA-223 regulates FOXO1 expression and cell proliferation. PMID: 22569260 Ref: Chloroquine enhances the chemotherapeutic activity of 5-fluorouracil in a colon cancer cell line via cell cycle alteration. PMID: 22716215 Ref: 6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest. PMID: 22719783 Ref: Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model. PMID: 23209640 Ref: Hath1 inhibits proliferation of colon cancer cells probably through up-regulating expression of Muc2 and p27 and down-regulating expression of cyclin D1. PMID: 23464457 |
Ref: miR-574-5p negatively regulates Qki6/7 to impact beta-catenin/Wnt signalling and the development of colorectal cancer. PMID: 22490519 Ref: PIK3CA overexpression is a possible prognostic factor for favorable survival in ovarian clear cell carcinoma. PMID: 22955107 Ref: Associations of beta-catenin alterations and MSI screening status with expression of key cell cycle regulating proteins and survival from colorectal cancer. PMID: 23337059 Ref: 3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer. PMID: 23341544 Ref: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells. PMID: 23363659 Ref: Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions. PMID: 23434653 Ref: Olean-12-eno[2,3-c] [1,2,5]oxadiazol-28-oic acid (OEOA) induces G1 cell cycle arrest and differentiation in human leukemia cell lines. PMID: 23696836 Ref: ERRalpha metabolic nuclear receptor controls growth of colon cancer cells. PMID: 23720198 Ref: Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions. PMID: 23844038 Ref: Particled Mica, STB-HO has chemopreventive potential via G1 arrest, and inhibition of proliferation and vascular endothelial growth factor receptor 2 in HCT colorectal cancer cells. PMID: 23883349 Ref: Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer. PMID: 24006921 Ref: Adiponectin and metformin additively attenuate IL1beta-induced malignant potential of colon cancer. PMID: 24157941 |
Ref: Interleukin-17F attenuates H2O2-induced cell cycle arrest. PMID: 24423465 Ref: Matrine inhibits proliferation and induces apoptosis of human colon cancer LoVo cells by inactivating Akt pathway. PMID: 24452711 Ref: MicroRNA-147 induces a mesenchymal-to-epithelial transition (MET) and reverses EGFR inhibitor resistance. PMID: 24454732 Ref: CELLFOOD induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways. PMID: 24598211 Ref: T-oligo as an anticancer agent in colorectal cancer. PMID: 24632202 Ref: Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome? PMID: 24728517 Ref: p27 expression in post-treatment rectal cancer: a potential novel approach for predicting residual nodal disease. PMID: 24814310 Ref: [Expression and significance of c-Jun activation domain binding protein 1 in human colorectal carcinoma]. PMID: 24854908 Ref: Nrdp1 inhibits growth of colorectal cancer cells by nuclear retention of p27. PMID: 24867101 Ref: Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Srcmediated phosphorylation of EGF receptor tyrosine kinase. PMID: 24890449 Ref: FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways. PMID: 25069037 Ref: Free radical derivatives formed from cyclooxygenase-catalyzed dihomo-gamma-linolenic acid peroxidation can attenuate colon cancer cell growth and enhance 5-fluorouracil's cytotoxicity. PMID: 25114837 Ref: Concomitant depletion of PTEN and p27 and overexpression of cyclin D1 may predict a worse prognosis for patients with post-operative stage II and III colorectal cancer. PMID: 25202365 Ref: Heme oxygenase-1 has antitumoral effects in colorectal cancer: involvement of p53. PMID: 25236576 Ref: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination. PMID: 25386076 Ref: Estradiol agonists inhibit human LoVo colorectal-cancer cell proliferation and migration through p53. PMID: 25469035 |
Ref: Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress. PMID: 24819444 Ref: MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients. PMID: 25256312 Ref: Myeloid cell leukemia-1 is associated with tumor progression by inhibiting apoptosis and enhancing angiogenesis in colorectal cancer. PMID: 25628923 Ref: Grainyhead-like 2 Promotes Tumor Growth and is Associated with Poor Prognosis in Colorectal Cancer. PMID: 25767604 Ref: Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells. PMID: 25861415 Ref: [(18)F]-FLT PET to predict early response to neoadjuvant therapy in KRAS wild-type rectal cancer: a pilot study. PMID: 25899481 Ref: Knockdown of biglycan expression by RNA interference inhibits the proliferation and invasion of, and induces apoptosis in, the HCT116 colon cancer cell line. PMID: 26459740 Ref: Pterostilbine, an active component of blueberries, sensitizes colon cancer cells to 5-fluorouracil cytotoxicity. PMID: 26472352 Ref: Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells. PMID: 26595875 Ref: Argentatin B Inhibits Proliferation of Prostate and Colon Cancer Cells by Inducing Cell Senescence. PMID: 26633316 |
Ref: The AhR is involved in the regulation of LoVo cell proliferation through cell cycle-associated proteins. PMID: 26861731 Ref: microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway. PMID: 27191497 Ref: Progesterone receptor activation is required for folic acid-induced anti-proliferation in colorectal cancer cell lines. PMID: 27233474 Ref: B-cell translocation gene 3 overexpression inhibits proliferation and invasion of colorectal cancer SW480 cells via Wnt/beta-catenin signaling pathway. PMID: 27468874 Ref: FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer. PMID: 27685445 Ref: Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action. PMID: 27716288 Ref: Stereoisomers of Astaxanthin Inhibit Human Colon Cancer Cell Growth by Inducing G2/M Cell Cycle Arrest and Apoptosis. PMID: 27726394 Ref: Effects and Mechanism of Imatinib in Inhibiting Colon Cancer Cell Proliferation. PMID: 27799652 Ref: Evaluation of anti-tumorigenic activity of BP3B against colon cancer with patient-derived tumor xenograft model. PMID: 27863496 |
Ref: Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression. PMID: 26824338 Ref: Cigarette smoke extracts induced the colon cancer migration via regulating epithelial mesenchymal transition and metastatic genes in human colon cancer cells. PMID: 27087172 Ref: Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells. PMID: 27862857 Ref: Loss of periplakin expression is associated with the tumorigenesis of colorectal carcinoma. PMID: 28068625 Ref: Anticancer and anti-inflammatory activities of girinimbine isolated from Murraya koenigii. PMID: 28096658 Ref: Identification of terpenoids from Rubus corchorifolius L. f. leaves and their anti-proliferative effects on human cancer cells. PMID: 28134947 Ref: Antitumorigenic effect of atmospheric-pressure dielectric barrier discharge on human colorectal cancer cells via regulation of Sp1 transcription factor. PMID: 28225083 Ref: Surface-bound galectin-4 regulates gene transcription and secretion of chemokines in human colorectal cancer cell lines. PMID: 28345468 Ref: New insights into the molecular mechanism of Boletus edulis ribonucleic acid fraction (BE3) concerning antiproliferative activity on human colon cancer cells. PMID: 28401225 Ref: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study. PMID: 28407690 Ref: P53-induced miR-30e-5p inhibits colorectal cancer invasion and metastasis by targeting ITGA6 and ITGB1. PMID: 28656629 Ref: YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway. PMID: 28740556 Ref: Antitumor effect of Quercetin on Y79 retinoblastoma cells via activation of JNK and p38 MAPK pathways. PMID: 29237430 Ref: NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway. PMID: 29296214 |
Ref: miR-133a-3p Targets SUMO-Specific Protease 1 to Inhibit Cell Proliferation and Cell Cycle Progress in Colorectal Cancer. PMID: 28748780 Ref: miR-1290 Contributes to Colorectal Cancer Cell Proliferation by Targeting INPP4B. PMID: 28915933 Ref: Knockdown of the long non-coding RNA HOTTIP inhibits colorectal cancer cell proliferation and migration and induces apoptosis by targeting SGK1. PMID: 29274585 Ref: Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27. PMID: 29456745 Ref: [Role of allograft inflammatory factor-1 in regulating the proliferation, migration and apoptosis of colorectal cancer cells]. PMID: 29891445 Ref: Cancer-associated fibroblasts enhance cell proliferation and metastasis of colorectal cancer SW480 cells by provoking long noncoding RNA UCA1. PMID: 29948578 Ref: Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide. PMID: 29993185 Ref: Manzamine A Exerts Anticancer Activity against Human Colorectal Cancer Cells. PMID: 30060617 Ref: Tenascin-C as a prognostic determinant of colorectal cancer through induction of epithelial-to-mesenchymal transition and proliferation. PMID: 30170017 Ref: Sorbus commixta water extract induces apoptotic cell death via a ROS-dependent pathway. PMID: 30197667 |