Primary Site >> Colorectal Cancer

Gene >> ID2

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Ref: Id2 is a target of the beta-catenin/T cell factor pathway in colon carcinoma.
PMID: 11572874
Ref: Expression of Id helix-loop-helix proteins in colorectal adenocarcinoma correlates with p53 expression and mitotic index.
PMID: 11751402
 Ref: 1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells.
PMID: 16007183
 Ref: Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations.
PMID: 18701504
Ref: Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver.
PMID: 18806828
 Ref: Dietary fiber enhances TGF-beta signaling and growth inhibition in the gut.
PMID: 21454444
Ref: Protein kinase Calpha signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium.
PMID: 21454537
Ref: Analysis of the role of the BMP7-Smad4-Id2 signaling pathway in SW480 colorectal carcinoma cells.
PMID: 21523323
 Ref: Down-regulation of Smad4 enhances proliferation and invasion of colorectal carcinoma HCT116 cells and up-regulates Id2.
PMID: 21956276
 Ref: Suppression of Src/ERK and GSK-3/beta-catenin signaling by pinosylvin inhibits the growth of human colorectal cancer cells.
PMID: 23333577
 Ref: Id2 deletion attenuates Apc-deficient ileal tumor formation.
PMID: 26163528
 Ref: The Wnt/beta-catenin signaling/Id2 cascade mediates the effects of hypoxia on the hierarchy of colorectal-cancer stem cells.
PMID: 26965643
 Ref: Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
PMID: 28767654