Primary Site >> Colorectal Cancer

Gene >> HTRA2

  • 2003
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  • 2017
Ref: Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
PMID: 12670894
Ref: Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
PMID: 12941843
Ref: [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers].
PMID: 15843754
Ref: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
PMID: 16998592
Ref: Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells.
PMID: 18176793
Ref: Participation of Omi Htra2 serine-protease activity in the apoptosis induced by cisplatin on SW480 colon cancer cells.
PMID: 18606591
Ref: Apoptosis-inducing factor and colon cancer.
PMID: 18061616
Ref: Inhibition of Human Pancreatic Cancer Cell Proliferation by Devil's Club Oplopanax horridus and Its Polyacetylene Bioactive Compound.
PMID: 26221768
Ref: YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways.
PMID: 29241219