Primary Site >> Colorectal Cancer
Gene >> HSPB1
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Ref: Effect of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on HSP70 and HSP28 gene expression and thermotolerance development in human colon carcinoma cells. PMID: 7802695 |
Ref: Heat shock proteins are differentially expressed in human gastrointestinal cancers. PMID: 8528482 |
Ref: Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27. PMID: 8647109 Ref: Heat-shock protein expression in cisplatin-sensitive and -resistant human tumor cells. PMID: 8824551 Ref: Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta. PMID: 8991187 |
Ref: HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs. PMID: 9205074 |
Ref: Heat shock protein 27 enhances the tumorigenicity of immunogenic rat colon carcinoma cell clones. PMID: 9850085 |
Ref: Preoperative treatment of rectal cancer with radiation, chemotherapy and hyperthermia: analysis of treatment efficacy and heat-shock response. PMID: 10190501 |
Ref: Differential anthracycline sensitivity in two related human colon carcinoma cell lines expressing similar levels of P-glycoprotein. PMID: 11248426 Ref: Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells. PMID: 11448946 |
Ref: Proteome analysis of butyrate-treated human colon cancer cells (HT-29). PMID: 11920611 Ref: Up-regulation of Hsp27 plays a role in the resistance of human colon carcinoma HT29 cells to photooxidative stress. PMID: 12126313 Ref: Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis. PMID: 12460647 |
Ref: Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases. PMID: 12633846 Ref: Tumor suppressor function of Betaig-h3 gene in radiation carcinogenesis. PMID: 12971413 |
Ref: Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis. PMID: 14604899 Ref: Heat shock protein 70 is induced in mouse human colon tumor xenografts after sublethal radiofrequency ablation. PMID: 15070600 Ref: Effective photoimmunotherapy of murine colon carcinoma induced by the combination of photodynamic therapy and dendritic cells. PMID: 15240542 |
Ref: Increased BNip3 and decreased mutant p53 in cisplatin-sensitive PDT-resistant HT29 cells. PMID: 15850808 Ref: Gefitinib-responsive EGFR-positive colorectal cancers have different proteome profiles from non-responsive cell lines. PMID: 16115757 Ref: The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells. PMID: 16289864 |
Ref: Dietary resistant starch type 3 prevents tumor induction by 1,2-dimethylhydrazine and alters proliferation, apoptosis and dedifferentiation in rat colon. PMID: 16597648 |
Ref: TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response. PMID: 17373661 Ref: Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer. PMID: 17376711 Ref: Heat shock protein 27 is associated with irinotecan resistance in human colorectal cancer cells. PMID: 17395183 Ref: Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues. PMID: 17431102 Ref: Differential proteomic analysis of human colorectal carcinoma cell lines metastasis-associated proteins. PMID: 17503081 Ref: Proteome analysis and tissue microarray for profiling protein markers associated with lymph node metastasis in colorectal cancer. PMID: 17542627 Ref: Photodynamic therapy resistant human colon carcinoma HT29 cells show cross-resistance to UVA but not UVC light. PMID: 17576382 Ref: Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells. PMID: 17640799 Ref: Thermal sensitization through ROS modulation: a strategy to improve the efficacy of hyperthermic intraperitoneal chemotherapy. PMID: 17723891 Ref: Hsp27 modulates p53 signaling and suppresses cellular senescence. PMID: 18089808 Ref: Proteasome inhibition potentiates the cytotoxic effects of hyperthermia in HT-29 colon cancer cells through inhibition of heat shock protein 27. PMID: 18337621 |
Ref: [Expression of HSP27 in colorectal carcinoma and its relationship with lymphatic metastasis]. PMID: 18227023 Ref: Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry. PMID: 18575723 Ref: Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil. PMID: 18757417 Ref: Modulation of intestinal environment by prebiotic germinated barley foodstuff prevents chemo-induced colonic carcinogenesis in rats. PMID: 18813820 Ref: Heat shock protein 27, a novel regulator of 5-fluorouracil resistance in colon cancer. PMID: 18949417 |
Ref: The role of Hsp27 and actin in the regulation of movement in human cancer cells responding to heat shock. PMID: 19224398 Ref: Comparative proteomic analysis of colon cancer cells in response to oxaliplatin treatment. PMID: 19520192 Ref: Using dual-tracer PET to predict the biologic behavior of human colorectal cancer. PMID: 19837754 Ref: Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11. PMID: 20093746 |
Ref: Identification of HSP27 as a potential tumor marker for colorectal cancer by the two-dimensional polyacrylamide gel electrophoresis. PMID: 19842058 Ref: [Expression and clinical significance of 14-3-3 sigma and heat shock protein 27 in colorectal cancer]. PMID: 20336542 Ref: A novel quinone-based derivative (DTNQ-Pro) induces apoptotic death via modulation of heat shock protein expression in Caco-2 cells. PMID: 20590589 Ref: Hepatocyte growth factor (HGF), heat shock proteins (HSPs) and multidrug resistance protein (MRP) expression in co-culture of colon tumor spheroids with normal cells after incubation with interleukin-1beta (IL-1beta) and/or camptothecin (CPT-11). PMID: 20726333 Ref: Low molecular weight heat shock protein HSP27 is a prognostic indicator in rectal cancer but not colon cancer. PMID: 20947885 Ref: Clinical significance of HSP27 expression in colorectal cancer. PMID: 21472339 |
Ref: Identification of biomarkers to improve diagnostic sensitivity of sporadic colorectal cancer in patients with low preoperative serum carcinoembryonic antigen by clinical proteomic analysis. PMID: 21185818 Ref: Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer. PMID: 21497196 Ref: Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4. PMID: 21521691 Ref: SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer. PMID: 21528083 Ref: Experimental study of HSP27 differential expression in left sided colon cancer and right sided colon cancer. PMID: 21566277 Ref: Lymphovascular invasion of colorectal cancer is correlated to SPARC expression in the tumor stromal microenvironment. PMID: 21725199 Ref: Cell to cell interaction in clusters enhances thermosensitivity in HT29 human colon cancer cells. PMID: 22024067 |
Ref: Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer. PMID: 21861207 Ref: Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics. PMID: 21989268 Ref: The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer. PMID: 22322011 Ref: Soluble HSPB1 regulates VEGF-mediated angiogenesis through their direct interaction. PMID: 22350794 Ref: Effects of hyperthermia on Hsp27 (HSPB1), Hsp72 (HSPA1A) and DNA repair proteins hMLH1 and hMSH2 in human colorectal cancer hMLH1-deficient and hMLH1-proficient cell lines. PMID: 22515340 Ref: High HSP27 and HSP70 expression levels are independent adverse prognostic factors in primary resected colon cancer. PMID: 22535481 Ref: ESM-1 regulates cell growth and metastatic process through activation of NF-kappaB in colorectal cancer. PMID: 22735811 Ref: Comparative proteomics analysis of colorectal cancer. PMID: 22799385 Ref: Suppression of heat shock protein 27 expression promotes 5-fluorouracil sensitivity in colon cancer cells in a xenograft model. PMID: 22842517 Ref: Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors. PMID: 22984537 Ref: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27. PMID: 23185379 |
Ref: HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53. PMID: 22982087 Ref: Comparative proteomic study for profiling differentially expressed proteins between Chinese left- and right-sided colon cancers. PMID: 23004678 Ref: Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis. PMID: 23017941 Ref: Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin alpha6beta4-dependent Akt, GSK-3beta, and HSF-1 in mesenchymal stem cells. PMID: 23538444 Ref: Evaluation of (1)(8)F-FDG and (1)(8)F-FLT for monitoring therapeutic responses of colorectal cancer cells to radiotherapy. PMID: 23639776 Ref: DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment. PMID: 23710334 Ref: [Antitumor effect of capsaicin on colorectal carcinoma xenograft in nude mice]. PMID: 23985252 |
Ref: MMP9 processing of HSPB1 regulates tumor progression. PMID: 24465581 Ref: Up-regulation of microRNA-145 associates with lymph node metastasis in colorectal cancer. PMID: 25019299 Ref: Inhibition of heat shock protein 27 phosphorylation promotes sensitivity to 5-fluorouracil in colorectal cancer cells. PMID: 25364415 |
Ref: The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells. PMID: 25544765 Ref: Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases. PMID: 25793600 Ref: Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines. PMID: 26043026 Ref: Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells. PMID: 26320187 |
Ref: Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity. PMID: 26861248 |
Ref: microRNA-577 suppresses tumor growth and enhances chemosensitivity in colorectal cancer. PMID: 28150434 Ref: Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF. PMID: 28182330 Ref: Re-examining HSPC1 inhibitors. PMID: 28255900 Ref: Comparative proteomics-network analysis of proteins responsible for ursolic acid-induced cytotoxicity in colorectal cancer cells. PMID: 28347227 Ref: Cetuximab promotes SN38 sensitivity via suppression of heat shock protein 27 in colorectal cancer cells with wild-type RAS. PMID: 28656305 Ref: Mechanism of reversal of multidrug resistance by curcumin in human colorectal cancer cell line HCT-8/5-FU. PMID: 28671249 Ref: EB1 protein alteration characterizes sporadic but not ulcerative colitis associated colorectal cancer. PMID: 28903393 Ref: Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis. PMID: 29403306 |
Ref: Knockdown of immature colon carcinoma transcript 1 induces suppression of proliferation, S-phase arrest and apoptosis in leukemia cells. PMID: 29328466 Ref: Heat shock protein 27 knockdown using nucleotidebased therapies enhances sensitivity to 5-FU chemotherapy in SW480 human colon cancer cells. PMID: 29328475 Ref: Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging. PMID: 29717105 Ref: shRNAinduced knockdown of the SPERT gene inhibits proliferation and promotes apoptosis of human colorectal cancer RKO cells. PMID: 29845259 Ref: Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation. PMID: 30056019 Ref: Decreasing O-GlcNAcylation affects the malignant transformation of MCF-7 cells via Hsp27 expression and its O-GlcNAc modification. PMID: 30106436 Ref: Hsp27 regulates epithelial mesenchymal transition, metastasis and proliferation in colorectal carcinoma. PMID: 30250600 |