Primary Site >> Colorectal Cancer
Gene >> HSF1
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Ref: Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells. PMID: 11322385 |
Ref: Induction of HSF1 expression is associated with sporadic colorectal cancer. PMID: 15457556 Ref: [Induction of HSF1 expression and sporadic colorectal cancer]. PMID: 15476319 |
Ref: Overexpression of heat shock factor 1 inhibits butyrate-induced differentiation in colon cancer cells. PMID: 17009592 |
Ref: [Expression of HSF1 and XAF1 in gastro-intestinal cancer]. PMID: 17884799 |
Ref: [Expression of heat-shock transcription factor 1 and X-linked inhibitor of apoptosis protein-associated factor-1 in gastrointestinal cancer]. PMID: 18546582 |
Ref: HSF1-mediated BAG3 expression attenuates apoptosis in 4-hydroxynonenal-treated colon cancer cells via stabilization of anti-apoptotic Bcl-2 proteins. PMID: 19179333 |
Ref: Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus containing constitutive HSF1 delivery to rodent tumors. PMID: 22613625 Ref: Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer. PMID: 22669480 |
Ref: Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin alpha6beta4-dependent Akt, GSK-3beta, and HSF-1 in mesenchymal stem cells. PMID: 23538444 Ref: Enhanced sensitivity of colon tumour cells to natural killer cell cytotoxicity after mild thermal stress is regulated through HSF1-mediated expression of MICA. PMID: 23902341 Ref: The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. PMID: 23983126 |
Ref: DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells. PMID: 25380824 |
Ref: ERK-dependent phosphorylation of HSF1 mediates chemotherapeutic resistance to benzimidazole carbamates in colorectal cancer cells. PMID: 25811962 Ref: Role of membrane Hsp70 in radiation sensitivity of tumor cells. PMID: 26197988 Ref: Heat shock factor 1 induces cancer stem cell phenotype in breast cancer cell lines. PMID: 26223813 Ref: Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics. PMID: 26320184 |
Ref: 2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression. PMID: 27922674 Ref: piR-823 contributes to colorectal tumorigenesis by enhancing the transcriptional activity of HSF1. PMID: 28618124 Ref: Vitexin confers HSF-1 mediated autophagic cell death by activating JNK and ApoL1 in colorectal carcinoma cells. PMID: 29348836 |
Ref: BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922. PMID: 29068469 Ref: Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis. PMID: 29730197 Ref: Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells. PMID: 29930764 |