Primary Site >> Colorectal Cancer
Gene >> HPRT1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Induction of increased salvage pathways of nucleotide synthesis by dosage effect due to chromosome imbalances may be fundamental in carcinogenesis: the example of colorectal carcinoma. PMID: 2424358 |
Ref: Inhibition of c-myc expression in human promyelocytic leukemia and colon adenocarcinoma cells by 6-thioguanine. PMID: 1702632 |
Ref: Relationship between the levels of purine salvage pathway enzymes and clinical/biological aggressiveness of human colon carcinoma. PMID: 7796389 Ref: Slippage--misalignment: to what extent does it contribute to mammalian cell mutagenesis? PMID: 7837971 Ref: [Synergistic cytotoxic effects of chemotherapy in colon tumor cells by simultaneous inhibition of de novo and salvage energy metabolism pathways]. PMID: 7941593 Ref: Mutator phenotypes in human colorectal carcinoma cell lines. PMID: 8022779 |
Ref: Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. PMID: 7824277 Ref: Molecular analysis of mutations in mutator colorectal carcinoma cell lines. PMID: 8589681 |
Ref: Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability. PMID: 8622858 Ref: Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype. PMID: 8649458 Ref: Loss of DNA mismatch repair in acquired resistance to cisplatin. PMID: 8674066 |
Ref: Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair. PMID: 9214593 Ref: A new T-lymphocyte cloning assay for detection of in vivo mutations in the human hypoxanthine-guanine phosphoribosyltransferase gene. PMID: 9258327 Ref: DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. PMID: 9294177 Ref: Mismatch repair defects and O6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells. PMID: 9353325 |
Ref: Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair. PMID: 9500919 Ref: Specificity of mutations in the PMS2-deficient human tumor cell line HEC-1-A. PMID: 9838164 |
Ref: New approaches to understanding p53 gene tumor mutation spectra. PMID: 10635987 |
Ref: Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability. PMID: 10822375 Ref: Specificity of mutations induced by the food-associated heterocyclic amine 2-amino-1-methyl-6-phenylimidazo-[4,5-b]-pyridine in colon cancer cell lines defective in mismatch repair. PMID: 10987307 |
Ref: Glycophosphatidylinositol-anchored protein deficiency as a marker of mutator phenotypes in cancer. PMID: 11212264 Ref: Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells. PMID: 11577013 Ref: The presence of single nucleotide instability in human breast cancer cell lines. PMID: 11691786 |
Ref: Effect of exogenous MSH6 and POLD1 expression on the mutation rate of the HPRT locus in a human colon cancer cell line with mutator phenotype, DLD-1. PMID: 14767555 Ref: Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization. PMID: 15519565 |
Ref: Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. PMID: 15543203 Ref: Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay. PMID: 15710547 |
Ref: Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair. PMID: 17178418 Ref: Cytostatic drug treatment causes seeding of gene promoter methylation. PMID: 17236756 |
Ref: Reverse transcription-quantitative polymerase chain reaction: description of a RIN-based algorithm for accurate data normalization. PMID: 19368728 Ref: Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells. PMID: 19861440 |
Ref: Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer. PMID: 20122155 Ref: Evidence of genetic instability in tumors and normal nearby tissues. PMID: 20186333 Ref: Evaluation of suitable reference genes for normalization of real-time reverse transcription PCR analysis in colon cancer. PMID: 21059236 |
Ref: Decreased expression of alpha-L-fucosidase gene FUCA1 in human colorectal tumors. PMID: 23965968 |
Ref: Expression stability of common housekeeping genes is differently affected by bowel inflammation and cancer: implications for finding suitable normalizers for inflammatory bowel disease studies. PMID: 24859296 |
Ref: Aldo-keto reductase 1B10 protects human colon cells from DNA damage induced by electrophilic carbonyl compounds. PMID: 26969882 |
Ref: Examination of Hypoxanthine Guanine Phosphoribosyltransferase as a biomarker for colorectal cancer patients. PMID: 30250925 |