Primary Site >> Biliary tract Cancer

Gene >> HPGD

  • 2013
  • 2014
  • 2015
Ref: 15-hydroxyprostaglandin dehydrogenase-derived 15-keto-prostaglandin E2 inhibits cholangiocarcinoma cell growth through interaction with peroxisome proliferator-activated receptor-gamma, SMAD2/3, and TAP63 proteins.
PMID: 23687300
 Ref: miR-21 targets 15-PGDH and promotes cholangiocarcinoma growth.
PMID: 24699315
 Ref: Omega-3 Polyunsaturated Fatty Acids Upregulate 15-PGDH Expression in Cholangiocarcinoma Cells by Inhibiting miR-26a/b Expression.
PMID: 25691459