Primary Site >> Colorectal Cancer

Gene >> HNRNPK

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  • 2018
Ref: Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer.
PMID: 16953238
Ref: Immunohistochemical detection of HSP27 and hnRNP K as prognostic and predictive biomarkers for colorectal cancer.
PMID: 21861207
Ref: Heterogeneous nuclear ribonucleoprotein (HnRNP) K genome-wide binding survey reveals its role in regulating 3'-end RNA processing and transcription termination at the early growth response 1 (EGR1) gene through XRN2 exonuclease.
PMID: 23857582
Ref: Role of MYC-regulated long noncoding RNAs in cell cycle regulation and tumorigenesis.
PMID: 25663692
Ref: Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells.
PMID: 25701787
Ref: A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation.
PMID: 26804170
Ref: Baseline MAPK signaling activity confers intrinsic radioresistance to KRAS-mutant colorectal carcinoma cells by rapid upregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K).
PMID: 27793696
Ref: Down-regulation of DAB2IP promotes colorectal cancer invasion and metastasis by translocating hnRNPK into nucleus to enhance the transcription of MMP2.
PMID: 28335083
Ref: MRPL33 and its splicing regulator hnRNPK are required for mitochondria function and implicated in tumor progression.
PMID: 28869607
Ref: Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression.
PMID: 29410604
Ref: Expression levels of hnRNP K and p21WAF1/CIP1 are associated with resistance to radiochemotherapy independent of p53 pathway activation in rectal adenocarcinoma.
PMID: 30272263