Primary Site >> Colorectal Cancer

Gene >> HMGCS2

  • 2003
  • 2006
  • 2015
  • 2017
Ref: Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site.
PMID: 12626711
Ref: Ketogenic HMGCS2 Is a c-Myc target gene expressed in differentiated cells of human colonic epithelium and down-regulated in colon cancer.
PMID: 16940161
Ref: The prognostic impact of lipid biosynthesis-associated markers, HSD17B2 and HMGCS2, in rectal cancer treated with neoadjuvant concurrent chemoradiotherapy.
PMID: 25929810
Ref: HMGCS2 enhances invasion and metastasis via direct interaction with PPARalpha to activate Src signaling in colorectal cancer and oral cancer.
PMID: 27816970
Ref: Ketogenesis contributes to intestinal cell differentiation.
PMID: 27935584
Ref: HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers.
PMID: 28468827
Ref: Predictive significance of HMGCS2 for prognosis in resected Chinese esophageal squamous cell carcinoma patients.
PMID: 28546759
Ref: hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC.
PMID: 29262657