Primary Site >> Liver Cancer

Gene >> HMGCR

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  • 2017
Ref: Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats.
PMID: 19527300
Ref: [Effect of interfering hepatocyte nuclear factor-1 alfa in HepG2 on the expressions of apoM, apoA-I and the correlative key enzyme of cholesterol metabolism].
PMID: 21492516
Ref: Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.
PMID: 24260365
Ref: Activated AMPK explains hypolipidemic effects of sulfated low molecular weight guluronate on HepG2 cells.
PMID: 25089813
Ref: MicroRNA-449 suppresses proliferation of hepatoma cell lines through blockade lipid metabolic pathway related to SIRT1.
PMID: 25119660
Ref: Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs.
PMID: 26646011
Ref: Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells.
PMID: 26771844
Ref: Pro-inflammation NF-kappaB signaling triggers a positive feedback via enhancing cholesterol accumulation in liver cancer cells.
PMID: 28100270