Primary Site >> Colorectal Cancer
Gene >> HMGB1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer. PMID: 12579287 |
Ref: Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages. PMID: 15743787 Ref: Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas. PMID: 15789216 |
Ref: Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas. PMID: 16118352 Ref: Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer. PMID: 16424007 Ref: Gene expression of tumor angiogenesis dissected: specific targeting of colon cancer angiogenic vasculature. PMID: 16794251 Ref: DNA repair pathway profiling and microsatellite instability in colorectal cancer. PMID: 16951227 |
Ref: Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer. PMID: 17376711 Ref: The role of trophinin, an adhesion molecule unique to human trophoblasts, in progression of colorectal cancer. PMID: 17487845 |
Ref: E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release. PMID: 18324679 Ref: Identification of potential genes/proteins regulated by Tiam1 in colorectal cancer by microarray analysis and proteome analysis. PMID: 18675922 Ref: [Role of high mobility group box 1 in adriamycin-induced apoptosis in leukemia K562 cells]. PMID: 18799030 |
Ref: Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers. PMID: 19506549 Ref: Suppression of dendritic cells by HMGB1 is associated with lymph node metastasis of human colon cancer. PMID: 19571604 Ref: Ethyl pyruvate administration inhibits hepatic tumor growth. PMID: 19584311 |
Ref: Human IgG antibody profiles differentiate between symptomatic patients with and without colorectal cancer. PMID: 19828471 Ref: Immunogenic death of colon cancer cells treated with oxaliplatin. PMID: 19881547 Ref: Overexpression of high-mobility group box 1 correlates with tumor progression and poor prognosis in human colorectal carcinoma. PMID: 19898867 Ref: Application of hyperthermia in addition to ionizing irradiation fosters necrotic cell death and HMGB1 release of colorectal tumor cells. PMID: 19968962 Ref: HMGB1 attenuates anti-metastatic defence of the liver in colorectal cancer. PMID: 20018503 Ref: HMGB1 attenuates anti-metastatic defense of the lymph nodes in colorectal cancer. PMID: 20185963 Ref: TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. PMID: 20526283 Ref: Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. PMID: 20616616 Ref: Analysis of nuclear high mobility group box 1 (HMGB1)-binding proteins in colon cancer cells: clustering with proteins involved in secretion and extranuclear function. PMID: 20812762 Ref: Co-expression of nuclear and cytoplasmic HMGB1 is inversely associated with infiltration of CD45RO+ T cells and prognosis in patients with stage IIIB colon cancer. PMID: 20846416 |
Ref: Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer. PMID: 21204727 Ref: Prognostic impact of DeltaTAp73 isoform levels and their target genes in colon cancer patients. PMID: 21807636 |
Ref: Diagnostic significance of serum HMGB1 in colorectal carcinomas. PMID: 22496788 Ref: Direct molecular interactions between HMGB1 and TP53 in colorectal cancer. PMID: 22647615 Ref: Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells. PMID: 22745684 Ref: High mobility group box-1 is phosphorylated by protein kinase C zeta and secreted in colon cancer cells. PMID: 22750245 Ref: Combined treatment of human colorectal tumor cell lines with chemotherapeutic agents and ionizing irradiation can in vitro induce tumor cell death forms with immunogenic potential. PMID: 22800185 |
Ref: Rage signalling promotes intestinal tumourigenesis. PMID: 22469986 Ref: Immunogenic cell death biomarkers HMGB1, RAGE, and DNAse indicate response to radioembolization therapy and prognosis in colorectal cancer patients. PMID: 23047645 Ref: A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers. PMID: 23640455 Ref: HMGB1 recruits myeloid derived suppressor cells to promote peritoneal dissemination of colon cancer after resection. PMID: 23707808 Ref: 5-Fluorouracil Induce the Expression of TLR4 on HCT116 Colorectal Cancer Cell Line Expressing Different Variants of TLR4. PMID: 24250621 Ref: Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells. PMID: 24464829 |
Ref: Cancer usurps skeletal muscle as an energy repository. PMID: 24197136 Ref: TLR4 is essential for dendritic cell activation and anti-tumor T-cell response enhancement by DAMPs released from chemically stressed cancer cells. PMID: 24362470 Ref: D-K6L 9 peptide combination with IL-12 inhibits the recurrence of tumors in mice. PMID: 24487722 Ref: Therapeutic potential of transgenic mesenchymal stem cells engineered to mediate anti-high mobility group box 1 activity: targeting of colon cancer. PMID: 24679698 Ref: The role of high mobility group box 1 (HMGB1) in colorectal cancer. PMID: 24681824 Ref: Electrochemotherapy with bleomycin induces hallmarks of immunogenic cell death in murine colon cancer cells. PMID: 25083316 Ref: Prognostic significance of high mobility group box 1 (HMGB1) expression in patients with colorectal cancer. PMID: 25275029 |
Ref: Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia. PMID: 24973890 Ref: 5-Fluorouracil causes leukocytes attraction in the peritoneal cavity by activating autophagy and HMGB1 release in colon carcinoma cells. PMID: 25098891 Ref: Effect of ulinastatin on the expression and distribution of high mobility group box 1 in human colon carcinoma cells in vitro. PMID: 25385285 Ref: The HMGB1 protein sensitizes colon carcinoma cells to cell death triggered by pro-apoptotic agents. PMID: 25434832 Ref: Graphene oxide as a chemosensitizer: diverted autophagic flux, enhanced nuclear import, elevated necrosis and improved antitumor effects. PMID: 25498801 Ref: High-mobility group box 1: a novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma. PMID: 25511739 Ref: Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells. PMID: 25560408 Ref: Immunohistochemical detection of high-mobility group box 1 correlates with resistance of preoperative chemoradiotherapy for lower rectal cancer: a retrospective study. PMID: 25622595 Ref: HMGB1-mediated autophagy modulates sensitivity of colorectal cancer cells to oxaliplatin via MEK/ERK signaling pathway. PMID: 25778491 Ref: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. PMID: 25906152 Ref: Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody. PMID: 25943534 Ref: Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway. PMID: 25953698 Ref: Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer. PMID: 25986235 Ref: High-mobility group box 1 protein activating nuclear factor-kappaB to upregulate vascular endothelial growth factor C is involved in lymphangiogenesis and lymphatic node metastasis in colon cancer. PMID: 26001393 Ref: Redox status of high-mobility group box 1 performs a dual role in angiogenesis of colorectal carcinoma. PMID: 26099505 Ref: [Expression of high mobility group box-1 in colorectal cancer and its clinical significance]. PMID: 26108781 Ref: p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses. PMID: 26183718 Ref: The irradiated-fibroblasts elicit immune response against tumor in a murine colon cancer model. PMID: 26241534 Ref: Extraction of Peptidoglycan from L. paracasei subp. Paracasei X12 and Its Preliminary Mechanisms of Inducing Immunogenic Cell Death in HT-29 Cells. PMID: 26305246 Ref: Integrated transcriptional profiling and genomic analyses reveal RPN2 and HMGB1 as promising biomarkers in colorectal cancer. PMID: 26388988 Ref: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice. PMID: 26693068 Ref: [Silencing HMGB1 expression by lentivirus-mediated small interfering RNA (siRNA) inhibits the proliferation and invasion of colorectal cancer LoVo cells in vitro and in vivo]. PMID: 26813430 |
Ref: The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells. PMID: 26913599 Ref: The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. PMID: 26948869 Ref: Mesenchymal-epithelial signalling in tumour microenvironment: role of high-mobility group Box 1. PMID: 26979829 Ref: Impact of Pattern Recognition Receptors on the Prognosis of Breast Cancer Patients Undergoing Adjuvant Chemotherapy. PMID: 27197163 Ref: HMGB1 knockdown effectively inhibits the progression of rectal cancer by suppressing HMGB1 expression and promoting apoptosis of rectal cancer cells. PMID: 27220399 Ref: Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype. PMID: 27323825 Ref: Immunogenic cell death due to a new photodynamic therapy (PDT) with glycoconjugated chlorin (G-chlorin). PMID: 27363018 Ref: HMGB1 overexpression as a prognostic factor for survival in cancer: a meta-analysis and systematic review. PMID: 27391431 Ref: Downregulation of HMGB1 by miR-34a is sufficient to suppress proliferation, migration and invasion of human cervical and colorectal cancer cells. PMID: 27456356 Ref: Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis. PMID: 27467932 Ref: The association of HMGB1 expression with clinicopathological significance and prognosis in Asian patients with colorectal carcinoma: a meta-analysis and literature review. PMID: 27540303 Ref: [HMGB1 as metabolic weapon in the arsenal of natural killer cells]. PMID: 27638530 Ref: Association of HMGB1 Gene Polymorphisms with Risk of Colorectal Cancer in a Chinese Population. PMID: 27665685 Ref: DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up. PMID: 27709558 Ref: Treatment effects of oxaliplatin combined with gemcitabine on colorectal cancer and its influence on HMGB1 expression. PMID: 27899980 Ref: Whole cell vaccination using immunogenic cell death by an oncolytic adenovirus is effective against a colorectal cancer model. PMID: 28035331 |
Ref: Postoperative changes in high mobility group box 1 levels after colorectal cancer surgery. PMID: 27834305 Ref: Colon cancer cell treatment with rose bengal generates a protective immune response via immunogenic cell death. PMID: 28151483 Ref: Killing colon cancer cells through PCD pathways by a novel hyaluronic acid-modified shell-core nanoparticle loaded with RIP3 in combination with chloroquine. PMID: 28199887 Ref: Calcium electroporation induces tumor eradication, long-lasting immunity and cytokine responses in the CT26 colon cancer mouse model. PMID: 28638724 Ref: MiR-216b functions as a tumor suppressor by targeting HMGB1-mediated JAK2/STAT3 signaling way in colorectal cancer. PMID: 29119054 Ref: High mobility group box 1 promotes sorafenib resistance in HepG2 cells and in vivo. PMID: 29246127 |
Ref: LncRNA MALAT1 induces colon cancer development by regulating miR-129-5p/HMGB1 axis. PMID: 29226325 Ref: HMGB1 suppresses colon carcinoma cell apoptosis triggered by coculture with dendritic cells via an ER stressassociated autophagy pathway. PMID: 29257231 Ref: Cytosolic high-mobility group box protein 1 (HMGB1) and/or PD-1+ TILs in the tumor microenvironment may be contributing prognostic biomarkers for patients with locally advanced rectal cancer who have undergone neoadjuvant chemoradiotherapy. PMID: 29270668 Ref: Modulated electro-hyperthermia induced loco-regional and systemic tumor destruction in colorectal cancer allografts. PMID: 29290768 Ref: Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer. PMID: 29487701 Ref: Induction of PIR-A/B(+) DCs in the in vitro inflammatory condition and their immunoregulatory function. PMID: 29508072 Ref: Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancer. PMID: 29535803 Ref: Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-alpha, and HMGB1. PMID: 29546074 Ref: Treatment of colon cancer with liver X receptor agonists induces immunogenic cell death. PMID: 29573475 Ref: The function and mechanism of HMGB1 in lung cancer and its potential therapeutic implications. PMID: 29725415 Ref: Metformin increases the cytotoxicity of oxaliplatin in human DLD-1 colorectal cancer cells through down-regulating HMGB1 expression. PMID: 29737584 Ref: Hemidesmus indicus induces immunogenic death in human colorectal cancer cells. PMID: 29849952 Ref: RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer-a Review. PMID: 29987748 Ref: Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway. PMID: 30066846 Ref: HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer. PMID: 30258050 |