Primary Site >> Stomach Cancer

Gene >> HK2

  • 2007
  • 2013
  • 2015
  • 2016
  • 2017
  • 2018
Ref: Expression of type 2 hexokinase and mitochondria-related genes in gastric carcinoma tissues and cell lines.
PMID: 17352240
Ref: [18F]Fluorodeoxyglucose accumulation as a biological marker of hypoxic status but not glucose transport ability in gastric cancer.
PMID: 23718763
Ref: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway.
PMID: 25333894
Ref: Inhibition of glucose-transporter 1 (GLUT-1) expression reversed Warburg effect in gastric cancer cell MKN45.
PMID: 25932183
Ref: MicroRNA-181b inhibits glycolysis in gastric cancer cells via targeting hexokinase 2 gene.
PMID: 27314295
Ref: Prognostic Significance of the Metabolic Marker Hexokinase-2 in Various Solid Tumors: A Meta-Analysis.
PMID: 27824926
Ref: Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
PMID: 28069585
Ref: Poor prognosis of hexokinase 2 overexpression in solid tumors of digestive system: a meta-analysis.
PMID: 28415659
Ref: Licochalcone A suppresses hexokinase 2-mediated tumor glycolysis in gastric cancer via downregulation of the Akt signaling pathway.
PMID: 29286170