Primary Site >> Colorectal Cancer

Gene >> HIPK2

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Ref: Nitric oxide prevents UV-induced phosphorylation of the p53 tumor-suppressor protein at serine 46: a possible role in inhibition of apoptosis.
PMID: 12927814
Ref: Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells.
PMID: 16467083
Ref: Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown.
PMID: 18483253
Ref: Tissue microarray cytometry reveals positive impact of homeodomain interacting protein kinase 2 in colon cancer survival irrespective of p53 function.
PMID: 21514416
Ref: Targeting COX-2/PGE(2) pathway in HIPK2 knockdown cancer cells: impact on dendritic cell maturation.
PMID: 23144866
Ref: Glucose restriction induces cell death in parental but not in homeodomain-interacting protein kinase 2-depleted RKO colon cancer cells: molecular mechanisms and implications for tumor therapy.
PMID: 23703384
Ref: Downregulation of serine/arginine-rich splicing factor 3 induces G1 cell cycle arrest and apoptosis in colon cancer cells.
PMID: 23503458
Ref: Verbascoside promotes apoptosis by regulating HIPK2-p53 signaling in human colorectal cancer.
PMID: 25282590
Ref: Homeodomain-interacting protein kinase 2 regulates DNA damage response through interacting with heterochromatin protein 1gamma.
PMID: 25151962
Ref: Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Deltae8 isoform.
PMID: 26625198
Ref: Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression.
PMID: 27096627
Ref: HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation.
PMID: 28060750