Primary Site >> Colorectal Cancer

Gene >> HIC1

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Ref: Association between CpG island methylation and microsatellite instability in colorectal cancer.
PMID: 9269998
Ref: Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer.
PMID: 11341745
Ref: Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood.
PMID: 15068392
Ref: Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer.
PMID: 15704048
Ref: The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.
PMID: 17087942
Ref: Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas.
PMID: 17143621
Ref: CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
PMID: 18204436
Ref: Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study.
PMID: 18313025
Ref: Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
PMID: 18798261
Ref: Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
PMID: 19002263
Ref: CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
PMID: 18832519
Ref: JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
PMID: 19107235
Ref: SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
PMID: 19430421
Ref: DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
PMID: 19470733
Ref: A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
PMID: 19686742
Ref: Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.
PMID: 20682398
Ref: Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
PMID: 21037082
Ref: Loss of a single Hic1 allele accelerates polyp formation in Apc(Delta716) mice.
PMID: 21297660
Ref: B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
PMID: 21738611
Ref: DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polyps.
PMID: 22020530
Ref: Methylation of the polycomb group target genes is a possible biomarker for favorable prognosis in colorectal cancer.
PMID: 23010642
Ref: KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.
PMID: 27540971
Ref: Methylation of the Tumor Suppressor Genes HIC1 and RassF1A Clusters Independently From the Methylation of Polycomb Target Genes in Colon Cancer.
PMID: 26671036
Ref: Reelin-Dab1 signaling system in human colorectal cancer.
PMID: 27434856
Ref: Screening of exon methylation biomarkers for colorectal cancer via LC-MS/MS strategy.
PMID: 28940471