Primary Site >> Colorectal Cancer

Gene >> HFE

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Ref: Cancer of the colon in an egg donor: policy repercussions for donor recruitment.
PMID: 9512262
 Ref: Colorectal cancer and HFE gene mutations.
PMID: 10329938
Ref: Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders.
PMID: 10383894
Ref: No evidence of increased risk of colorectal cancer in individuals heterozygous for the Cys282Tyr haemochromatosis mutation.
PMID: 10634155
 Ref: Interaction between haemochromatosis and transferrin receptor genes in hepatocellular carcinoma.
PMID: 11096344
 Ref: Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
PMID: 12529348
Ref: Health implications of iron overload: the role of diet and genotype.
PMID: 12674437
Ref: Re: Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.
PMID: 12783939
Ref: Heterozygosity for the Cys282Tyr mutation in the HFE gene and the risk of colorectal cancer (Netherlands).
PMID: 12948285
 Ref: Iron supplementation in athletes--first do no harm.
PMID: 15212743
 Ref: Hemochromatosis gene mutations and distal adenomatous colorectal polyps.
PMID: 15668490
Ref: Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer.
PMID: 15941956
 Ref: Haemochromatosis HFE gene polymorphisms as potential modifiers of hereditary nonpolyposis colorectal cancer risk and onset age.
PMID: 19291797
 Ref: HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.
PMID: 20099304
 Ref: Effects of selenium on colon carcinogenesis induced by azoxymethane and dextran sodium sulfate in mouse model with high-iron diet.
PMID: 21826154
 Ref: Screening for hereditary haemochromatosis.
PMID: 22198253
Ref: Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting.
PMID: 22469802
 Ref: HFE gene C282Y variant is associated with colorectal cancer in Caucasians: a meta-analysis.
PMID: 23553028
 Ref: Gender and plasma iron biomarkers, but not HFE gene mutations, increase the risk of colorectal cancer and polyps.
PMID: 25854174
Ref: Meta-Analysis of the Association between H63D and C282Y Polymorphisms in HFE and Cancer Risk.
PMID: 26107216
Ref: Implicating the H63D polymorphism in the HFE gene in increased incidence of solid cancers: a meta-analysis.
PMID: 26535689
 Ref: The risk of new-onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants.
PMID: 26893171
 Ref: Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells.
PMID: 28937159