Primary Site >> Colorectal Cancer

Gene >> HEY2

  • 2001
  • 2006
  • 2007
Ref: Elevated expression of SAG/ROC2/Rbx2/Hrt2 in human colon carcinomas: SAG does not induce neoplastic transformation, but antisense SAG transfection inhibits tumor cell growth.
PMID: 11255265
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Notch signaling in gastrointestinal tract (review).
PMID: 17143535
Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer.
PMID: 17611704