Primary Site >> Colorectal Cancer

Gene >> HEY1

  • 2006
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  • 2018
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Notch signaling in gastrointestinal tract (review).
PMID: 17143535
Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer.
PMID: 17611704
Ref: Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.
PMID: 23900217
Ref: Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.
PMID: 24265293
Ref: Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.
PMID: 27460529
Ref: Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
PMID: 27880939
Ref: Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer.
PMID: 29879147
Ref: Modification of alpha2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
PMID: 29981167