Primary Site >> Stomach Cancer

Gene >> HES1

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Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Hath1 up-regulates gastric mucin gene expression in gastric cells.
PMID: 16647036
 Ref: Notch signaling in gastrointestinal tract (review).
PMID: 17143535
Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer.
PMID: 17611704
 Ref: Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53.
PMID: 18813803
 Ref: Over-activated Notch-1 protects gastric carcinoma BGC-823 cells from TNFalpha-induced apoptosis.
PMID: 19403345
 Ref: Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers.
PMID: 21466361
Ref: Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.
PMID: 22249198
 Ref: Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.
PMID: 22691042
Ref: ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-kappaB-dependent and Notch-independent mechanism.
PMID: 22781708
Ref: Notch2 regulates matrix metallopeptidase 9 via PI3K/AKT signaling in human gastric carcinoma cell MKN-45.
PMID: 23326131
 Ref: An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer.
PMID: 24317510
Ref: Gastric cancer cell growth and epithelial-mesenchymal transition are inhibited by gamma-secretase inhibitor DAPT.
PMID: 24932308
Ref: Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits.
PMID: 24944018
Ref: Role of Notch signaling pathway in gastric cancer: a meta-analysis of the literature.
PMID: 25083094
Ref: [Effect of siRNA-mediated silencing of Notch2 on proliferation of the HepG2 human hepatocellular carcinoma cells].
PMID: 25180870
Ref: Xiaotan Sanjie decoction attenuates tumor angiogenesis by manipulating Notch-1-regulated proliferation of gastric cancer stem-like cells.
PMID: 25278704
 Ref: Gastric tumor-initiating CD44(+) cells and epithelial-mesenchymal transition are inhibited by gamma-secretase inhibitor DAPT.
PMID: 26722328
 Ref: Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44(+) Gastric Cancer Stem Cells.
PMID: 28186678
Ref: Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro.
PMID: 28416750
Ref: Inhibition of Hes1 enhances lapatinib sensitivity in gastric cancer sphere-forming cells.
PMID: 28959362
 Ref: In vivo and in vitro effects of microRNA-124 on human gastric cancer by targeting JAG1 through the Notch signaling pathway.
PMID: 28941308
Ref: Effect of lenalidomide on the human gastric cancer cell line SGC7901/vincristine Notch signaling.
PMID: 29578180