Primary Site >> Liver Cancer

Gene >> HDAC4

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Ref: Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.
PMID: 18593903
Ref: Growth inhibition and gene induction in human hepatocellular carcinoma cell exposed to sodium 4-phenylbutanoate.
PMID: 19024104
Ref: microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity.
PMID: 20842113
Ref: The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma.
PMID: 21837748
Ref: Anticancer effects of sodium butyrate on hepatocellular carcinoma cells in vitro.
PMID: 23440283
Ref: Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers.
PMID: 24079712
Ref: Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: recruiting histone deacetylase and inhibiting activator protein 1 transcription factors.
PMID: 25051397
Ref: The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.
PMID: 26366213
Ref: 14-3-3zeta promotes hepatocellular carcinoma venous metastasis by modulating hypoxia-inducible factor-1alpha.
PMID: 26910835
Ref: Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes.
PMID: 27119349
Ref: Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy.
PMID: 28386016
Ref: Targeting histone deacetylase 4/ubiquitin-conjugating enzyme 9 impairs DNA repair for radiosensitization of hepatocellular carcinoma cells in mice.
PMID: 28646552
Ref: Hepatic stellate cell-specific deletion of SIRT1 exacerbates liver fibrosis in mice.
PMID: 28919365
Ref: MiR-520b restrains cell growth by targeting HDAC4 in lung cancer.
PMID: 30106218