Primary Site >> Colorectal Cancer
Gene >> HAS3
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Ref: Hyaluronan synthase-3 is upregulated in metastatic colon carcinoma cells and manipulation of expression alters matrix retention and cellular growth. PMID: 14566823 |
Ref: Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer. PMID: 15065603 Ref: Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44. PMID: 15231668 Ref: Hyaluronan mediates adhesion of metastatic colon carcinoma cells. PMID: 15522317 |
Ref: Inhibition of hyaluronan synthases decreases matrix metalloproteinase-7 (MMP-7) expression and activity. PMID: 19231585 |
Ref: Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth in mice. PMID: 20305449 |
Ref: Inhibition of hyaluronan synthase-3 decreases subcutaneous colon cancer growth by increasing apoptosis. PMID: 21453239 |
Ref: FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes. PMID: 22934709 Ref: Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/beta-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]. PMID: 23922913 |