Primary Site >> Colorectal Cancer
Gene >> GSTT1
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Ref: Glutathione S-transferase M1 and T1 polymorphisms: susceptibility to colon cancer and age of onset. PMID: 7614702 |
Ref: Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers. PMID: 8625505 Ref: Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma. PMID: 8824506 |
Ref: Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients. PMID: 9511178 Ref: Glutathione S-transferase GSTM1 and GSTT1 polymorphisms and colorectal cancer risk: a prospective study. PMID: 9829708 Ref: Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer. PMID: 9834266 Ref: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. PMID: 10026993 |
Ref: Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma. PMID: 10096244 Ref: Polymorphisms in GSTP1, GSTM1, and GSTT1 and susceptibility to colorectal cancer. PMID: 10207630 Ref: Polymorphism of glutathione S-transferase loci GSTM1 and GSTT1 and susceptibility to colorectal cancer in Egypt. PMID: 10424787 Ref: Induction of genetic damage in human lymphocytes and mutations in Salmonella by trihalomethanes: role of red blood cells and GSTT1-1 polymorphism. PMID: 10473651 Ref: The glutathione S-transferases: influence of polymorphism on cancer susceptibility. PMID: 10493261 |
Ref: Glutathione S-transferase polymorphisms and colorectal cancer: a HuGE review. PMID: 10625170 |
Ref: Glutathione S-transferase polymorphisms and risk of colorectal adenomas. PMID: 11165755 Ref: Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factor. PMID: 11408349 Ref: Glutathione S-transferase M1 and T1 null genotypes and the risk of gastric and colorectal cancers. PMID: 11410321 Ref: Metabolic genotypes and risk for colorectal cancer. PMID: 11422615 Ref: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype. PMID: 11448648 Ref: Polymorphisms and colorectal tumor risk. PMID: 11487538 |
Ref: Arylamine N-acetyltransferase type 2 and glutathione S-transferases M1 and T1 polymorphisms in familial adenomatous polyposis. PMID: 11773864 Ref: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. PMID: 12072547 Ref: Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer. PMID: 12210502 Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. PMID: 12419832 Ref: Low-penetrance genes and their involvement in colorectal cancer susceptibility. PMID: 12433710 Ref: Glutathione S-transferase (GSTM1 and GSTT1)-dependent risk for colorectal cancer. PMID: 12530094 |
Ref: Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation. PMID: 12579293 Ref: Possible influence of glutathione S-transferase GSTT1 null genotype on age of onset of sporadic colorectal adenocarcinoma. PMID: 12682546 Ref: No modifying effect of NAT1, GSTM1, and GSTT1 on the relation between smoking and colorectal cancer risk. PMID: 12869413 Ref: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. PMID: 12896903 |
Ref: Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer. PMID: 15069679 Ref: A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer. PMID: 15213713 Ref: Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk. PMID: 15319294 Ref: Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. PMID: 15352038 Ref: Polymorphisms of glutathione-S-transferase and arylamine N-acetyltransferase enzymes and susceptibility to colorectal cancer. PMID: 15736440 Ref: [Associations between genetic polymorphisms of glutathione S-transferase M1 and T1, smoking and susceptibility to colorectal cancer: a case-control study]. PMID: 15777499 |
Ref: Relationship between metabolic enzyme polymorphism and colorectal cancer. PMID: 15637738 Ref: Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan. PMID: 15770723 Ref: Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphisms. PMID: 15840612 Ref: Glutathione S-transferase M1, T1, P1 genotypes and risk for development of colorectal cancer. PMID: 15932063 Ref: Glutathione S-transferase T1 polymorphisms are associated with outcome in colorectal cancer. PMID: 16051638 Ref: [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer]. PMID: 16471212 |
Ref: Exploring SNP-SNP interactions and colon cancer risk using polymorphism interaction analysis. PMID: 16217767 Ref: GSTM1 and GSTT1 polymorphisms, cigarette smoking, and risk of colon cancer: a population-based case-control study in North Carolina (United States). PMID: 16596290 Ref: [Association between genetic polymorphisms of metabolic enzymes and susceptibility of colorectal cancer]. PMID: 16620591 Ref: Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland. PMID: 16823842 Ref: The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. PMID: 16829689 Ref: Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients. PMID: 16865249 Ref: Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans. PMID: 16886896 Ref: Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients. PMID: 17119063 |
Ref: Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan. PMID: 17191090 Ref: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas. PMID: 18093316 |
Ref: Measuring the effects of genes and environment on complex traits. PMID: 18453084 Ref: GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer. PMID: 18630481 Ref: Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. PMID: 18768509 |
Ref: Urinary isothiocyanates; glutathione S-transferase M1, T1, and P1 polymorphisms; and risk of colorectal cancer: the Multiethnic Cohort Study. PMID: 19124514 Ref: Polymorphisms of biotransforming enzymes (GSTs) and their association with colorectal cancer in the Slovak population. PMID: 19580344 Ref: Gene-smoking interaction on colorectal adenoma and cancer risk: review and meta-analysis. PMID: 19589345 Ref: [Genetic polymorphism in patients with colorectal and with head and neck cancer]. PMID: 19643719 Ref: Glutathione S-transferase polymorphisms and survival in African-American and white colorectal cancer patients. PMID: 19748847 Ref: Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population. PMID: 19960570 Ref: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy. PMID: 20445800 |
Ref: An updating meta-analysis of the glutathione S-transferase T1 polymorphisms and colorectal cancer risk: a HuGE review. PMID: 19798506 Ref: Protein carbonyl levels, glutathione S-transferase polymorphisms and risk of colorectal cancer. PMID: 19933708 Ref: Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy. PMID: 20017670 Ref: Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk. PMID: 20042523 Ref: Genetic polymorphism of glutathione S-transferase T1 and the risk of colorectal cancer: a meta-analysis. PMID: 20061204 Ref: GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis. PMID: 20207535 Ref: Cigarette smoking, genetic polymorphisms and colorectal cancer risk: the Fukuoka Colorectal Cancer Study. PMID: 20534171 Ref: Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. PMID: 20878130 |
Ref: Genetic polymorphisms of glutathione S-transferase genes and susceptibility to colorectal cancer: a case-control study in an Indian population. PMID: 20688591 Ref: Glutathione S-transferase (GST) gene polymorphisms, cigarette smoking and colorectal cancer risk among Chinese in Singapore. PMID: 21803734 Ref: Null genotype of GSTT1 contributes to colorectal cancer risk in Asian populations: evidence from a meta-analysis. PMID: 22296370 |
Ref: Null genotype of glutathione S-transferase Tl contributes to colorectal cancer risk in the Asian population: a meta-analysis. PMID: 21916987 Ref: Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran. PMID: 22228187 Ref: Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy. PMID: 22234881 Ref: GSTM1 and GSTT1 polymorphisms and colorectal cancer risk in Chinese population: a meta-analysis. PMID: 22237425 Ref: Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population. PMID: 22697302 Ref: Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients. PMID: 22909207 |
Ref: Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study. PMID: 22415791 Ref: Systematic review: diet-gene interactions and the risk of colorectal cancer. PMID: 23216531 Ref: Glutathione S-transferase M1-null genotype as risk factor for SOS in oxaliplatin-treated patients with metastatic colorectal cancer. PMID: 23287989 Ref: Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer. PMID: 23314736 Ref: Differential toxicity biomarkers for irinotecan- and oxaliplatin-containing chemotherapy in colorectal cancer. PMID: 23543295 Ref: Glutathione S-transferase T1 gene polymorphism and colorectal cancer risk: an updated analysis. PMID: 23773486 Ref: GST gene variants in synchronous colorectal cancers and synchronous association of colorectal cancers with other cancers. PMID: 23790786 Ref: Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy. PMID: 23894404 Ref: Cytotoxic and anti-inflammatory effects of onion peel extract on lipopolysaccharide stimulated human colon carcinoma cells. PMID: 24001438 Ref: Polymorphisms of GSTP1, ERCC2 and TS-3'UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients. PMID: 24137384 |
Ref: Cruciferous vegetables, glutathione S-transferase polymorphisms, and the risk of colorectal cancer among Chinese men. PMID: 24238877 Ref: Polymorphisms of glutathione-S-transferases M1, T1, P1 and susceptibility to colorectal cancer in a sample of the Tunisian population. PMID: 24254297 Ref: Cruciferous vegetables and risk of colorectal neoplasms: a systematic review and meta-analysis. PMID: 24341734 Ref: GSTT1 is deregulated in left colon tumors. PMID: 24716977 Ref: Genetic variants in the glutathione S-transferase genes and survival in colorectal cancer patients after chemotherapy and differences according to treatment with oxaliplatin. PMID: 24842074 Ref: Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option. PMID: 25167226 Ref: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients. PMID: 25370899 Ref: Association between glutathione S-transferase T1, M1, and P1 genotypes and the risk of colorectal cancer. PMID: 25408579 |
Ref: Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan. PMID: 25249451 Ref: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy. PMID: 25677447 Ref: Association between glutathione S-transferase M1 and T1 polymorphisms and colorectal cancer risk in patients from Kazakhstan. PMID: 25807650 Ref: Epidemiological factors related to GSTM1 and GSTT1 genes deletion in colon and rectum cancers: A case-control study. PMID: 26406947 |
Ref: Can GSTM1 and GSTT1 polymorphisms predict clinical outcomes of chemotherapy in gastric and colorectal cancers? A result based on the previous reports. PMID: 27382306 Ref: Glutathione S-transferase T1, M1 and P1 Genetic Polymorphisms and Susceptibility to Colorectal Cancer in Turkey. PMID: 27644629 Ref: Evaluation of deletion polymorphisms of glutathione S-transferase genes and colorectal cancer risk in ethnic Kashmiri population: A case-control study. PMID: 28485343 |
Ref: The Interaction of Smoking with Gene Polymorphisms on Four Digestive Cancers: A Systematic Review and Meta-Analysis. PMID: 29721061 Ref: GSTM1, GSTT1, and GSTP1 polymorphisms and colorectal cancer risk in Polish nonsmokers. PMID: 29765533 Ref: Expression of CYP and GST in human normal and colon tumor tissues. PMID: 30092668 Ref: The diagnostic potential of glutathione S-transferase (GST) polymorphisms in patients with colorectal cancer. PMID: 30106268 Ref: Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer. PMID: 30356976 |