Primary Site >> Colorectal Cancer
Gene >> GSTM1
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Ref: Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. PMID: 8403204 |
Ref: Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer. PMID: 7498640 Ref: Glutathione S-transferase M1 and T1 polymorphisms: susceptibility to colon cancer and age of onset. PMID: 7614702 |
Ref: Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers. PMID: 8625505 Ref: Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma. PMID: 8824506 Ref: Glutathione S-transferase M1 genotypes and the risk of anal cancer: a population-based case-control study. PMID: 8959321 Ref: The polymorphism of GSTM1, mutagen sensitivity in colon cancer and healthy control. PMID: 9003527 |
Ref: Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking. PMID: 9107426 Ref: Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2. PMID: 9202749 Ref: Pilot study of free and conjugated urinary mutagenicity during consumption of pan-fried meats: possible modulation by cruciferous vegetables, glutathione S-transferase-M1, and N-acetyltransferase-2. PMID: 9403034 |
Ref: Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients. PMID: 9511178 Ref: Urinary mutagenicity on TA98 and YG1024 Salmonella typhimurium strains after a hamburger meal: influence of GSTM1 and NAT2 genotypes. PMID: 9568593 Ref: Glutathione S-transferase GSTM1 and GSTT1 polymorphisms and colorectal cancer risk: a prospective study. PMID: 9829708 Ref: Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer. PMID: 9834266 Ref: NAT2, GSTM-1, cigarette smoking, and risk of colon cancer. PMID: 9865425 Ref: Polymorphisms in xenobiotic conjugation and disease predisposition. PMID: 10022251 Ref: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. PMID: 10026993 |
Ref: Meat consumption, genetic susceptibility, and colon cancer risk: a United States multicenter case-control study. PMID: 9950235 Ref: Glutathione S-transferase T1 and M1 genotypes in normal mucosa, transitional mucosa and colorectal adenocarcinoma. PMID: 10096244 Ref: Polymorphisms in GSTP1, GSTM1, and GSTT1 and susceptibility to colorectal cancer. PMID: 10207630 Ref: Polymorphism of glutathione S-transferase loci GSTM1 and GSTT1 and susceptibility to colorectal cancer in Egypt. PMID: 10424787 Ref: Glutathione S-transferase (GST) M1, T1, P1, N-acetyltransferase (NAT) 1 and 2 genetic polymorphisms and susceptibility to colorectal cancer. PMID: 10434361 Ref: Polymorphism of GSTM1 gene in patients with colorectal cancer and colonic polyps. PMID: 10445390 Ref: The glutathione S-transferases: influence of polymorphism on cancer susceptibility. PMID: 10493261 Ref: Genotypes of glutathione S-transferase M1 and N-acetyltransferase 2 in Japanese patients with gastric cancer. PMID: 11957090 |
Ref: Glutathione S-transferase polymorphisms and colorectal cancer: a HuGE review. PMID: 10625170 Ref: Western diet, family history of colorectal cancer, NAT2, GSTM-1 and risk of colon cancer. PMID: 10680724 Ref: Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes. PMID: 10769717 Ref: The glutathione S-transferase M1 genotype in ovarian cancer. PMID: 10868693 Ref: No association of glutathione S-transferase M1 gene polymorphism with diabetic nephropathy in Japanese type 2 diabetic patients. PMID: 10901185 Ref: Interplay between dietary inducers of GST and the GSTM-1 genotype in colon cancer. PMID: 10925368 Ref: Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer. PMID: 11059519 Ref: Associations between family history of cancer and genes coding for metabolizing enzymes (United States). PMID: 11075868 Ref: Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. PMID: 11133820 |
Ref: Glutathione S-transferase polymorphisms and risk of colorectal adenomas. PMID: 11165755 Ref: Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factor. PMID: 11408349 Ref: Glutathione S-transferase M1 and T1 null genotypes and the risk of gastric and colorectal cancers. PMID: 11410321 Ref: Metabolic genotypes and risk for colorectal cancer. PMID: 11422615 Ref: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype. PMID: 11448648 Ref: Polymorphisms and colorectal tumor risk. PMID: 11487538 |
Ref: Arylamine N-acetyltransferase type 2 and glutathione S-transferases M1 and T1 polymorphisms in familial adenomatous polyposis. PMID: 11773864 Ref: Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype. PMID: 11809532 Ref: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. PMID: 12072547 Ref: Meat consumption, cigarette smoking, and genetic susceptibility in the etiology of colorectal cancer: results from a Dutch prospective study. PMID: 12074508 Ref: GSTM-1 and NAT2 and genetic alterations in colon tumors. PMID: 12195642 Ref: Genetic polymorphisms in the cytochrome P450 1A1, glutathione S-transferase M1 and T1, and susceptibility to colon cancer. PMID: 12210502 Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. PMID: 12419832 Ref: Low-penetrance genes and their involvement in colorectal cancer susceptibility. PMID: 12433710 Ref: Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. PMID: 12507929 Ref: Glutathione S-transferase (GSTM1 and GSTT1)-dependent risk for colorectal cancer. PMID: 12530094 |
Ref: Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation. PMID: 12579293 Ref: Possible influence of glutathione S-transferase GSTT1 null genotype on age of onset of sporadic colorectal adenocarcinoma. PMID: 12682546 Ref: No modifying effect of NAT1, GSTM1, and GSTT1 on the relation between smoking and colorectal cancer risk. PMID: 12869413 Ref: Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. PMID: 12896903 Ref: Interaction between smoking, GSTM1 deletion and colorectal cancer: results from the GSEC study. PMID: 12944179 Ref: Associations between smoking, passive smoking, GSTM-1, NAT2, and rectal cancer. PMID: 14504199 Ref: A meta-analysis of 20 case-control studies of the glutathione S-transferase M1 (GSTM1) status and colorectal cancer risk. PMID: 14523342 Ref: Genetic polymorphisms and modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in human lymphocytes. PMID: 14601045 |
Ref: Meat consumption patterns and preparation, genetic variants of metabolic enzymes, and their association with rectal cancer in men and women. PMID: 15051825 Ref: Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer. PMID: 15069679 Ref: A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer. PMID: 15213713 Ref: Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk. PMID: 15319294 Ref: Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer. PMID: 15352038 Ref: CYP1A1, cigarette smoking, and colon and rectal cancer. PMID: 15496536 Ref: Genomic heterogeneity and instability in colorectal cancer: spectral karyotyping, glutathione transferase-Ml and ras. PMID: 15542115 Ref: Polymorphisms of glutathione-S-transferase and arylamine N-acetyltransferase enzymes and susceptibility to colorectal cancer. PMID: 15736440 Ref: [Associations between genetic polymorphisms of glutathione S-transferase M1 and T1, smoking and susceptibility to colorectal cancer: a case-control study]. PMID: 15777499 |
Ref: Relationship between metabolic enzyme polymorphism and colorectal cancer. PMID: 15637738 Ref: The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women. PMID: 15671210 Ref: Vegetable/fruit, smoking, glutathione S-transferase polymorphisms and risk for colorectal cancer in Taiwan. PMID: 15770723 Ref: Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphisms. PMID: 15840612 Ref: Glutathione S-transferase M1, T1, P1 genotypes and risk for development of colorectal cancer. PMID: 15932063 Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. PMID: 16006997 Ref: [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer]. PMID: 16471212 Ref: [Glutathione S-transferase M1 polymorphism and the risk on colorectal cancer: a multilevel meta regression]. PMID: 16676598 |
Ref: Polymorphisms in the glutathione S-transferase mu cluster are associated with tumour progression and patient outcome in colorectal cancer. PMID: 16328000 Ref: Validation of the use of DNA pools and primer extension in association studies of sporadic colorectal cancer for selection of candidate SNPs. PMID: 16395669 Ref: GSTM1 and GSTT1 polymorphisms, cigarette smoking, and risk of colon cancer: a population-based case-control study in North Carolina (United States). PMID: 16596290 Ref: [Association between genetic polymorphisms of metabolic enzymes and susceptibility of colorectal cancer]. PMID: 16620591 Ref: Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: a case-control study in the Grampian region of Scotland. PMID: 16823842 Ref: The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. PMID: 16829689 Ref: Expression of the glutathione enzyme system of human colon mucosa by localisation, gender and age. PMID: 16846540 Ref: Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients. PMID: 16865249 Ref: Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans. PMID: 16886896 Ref: Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility. PMID: 17010218 Ref: Genetic polymorphisms in xenobiotic clearance genes and their influence on disease expression in hereditary nonpolyposis colorectal cancer patients. PMID: 17119063 Ref: Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis. PMID: 17178849 |
Ref: Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan. PMID: 17191090 Ref: Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. PMID: 17603900 Ref: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas. PMID: 18093316 Ref: Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking. PMID: 18159984 |
Ref: GSTM, GSTT and p53 polymorphisms as modifiers of clinical outcome in colorectal cancer. PMID: 18630481 Ref: Genetic variation in genes for the xenobiotic-metabolizing enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and susceptibility to colorectal cancer in Lynch syndrome. PMID: 18768509 |
Ref: Urinary isothiocyanates; glutathione S-transferase M1, T1, and P1 polymorphisms; and risk of colorectal cancer: the Multiethnic Cohort Study. PMID: 19124514 Ref: Somatic alterations, metabolizing genes and smoking in rectal cancer. PMID: 19358278 Ref: GSTM1 and NAT2 polymorphisms and colon, lung and bladder cancer risk: a case-control study. PMID: 19443391 Ref: Polymorphisms of biotransforming enzymes (GSTs) and their association with colorectal cancer in the Slovak population. PMID: 19580344 Ref: Gene-smoking interaction on colorectal adenoma and cancer risk: review and meta-analysis. PMID: 19589345 Ref: [Genetic polymorphism in patients with colorectal and with head and neck cancer]. PMID: 19643719 Ref: Glutathione S-transferase polymorphisms and survival in African-American and white colorectal cancer patients. PMID: 19748847 Ref: Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population. PMID: 19960570 Ref: Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy. PMID: 20445800 |
Ref: Protein carbonyl levels, glutathione S-transferase polymorphisms and risk of colorectal cancer. PMID: 19933708 Ref: Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy. PMID: 20017670 Ref: Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk. PMID: 20042523 Ref: Glutathione S-transferase M1 polymorphism and sporadic colorectal cancer risk: An updating meta-analysis and HuGE review of 36 case-control studies. PMID: 20123161 Ref: GSTM1, GSTT1, GSTP1, GSTA1 and colorectal cancer risk: a comprehensive meta-analysis. PMID: 20207535 Ref: Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk. PMID: 20375710 Ref: Serum glutathione transferase does not respond to indole-3-carbinol: A pilot study. PMID: 20526440 Ref: Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. PMID: 20878130 Ref: Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. PMID: 20937634 |
Ref: Genetic polymorphisms of glutathione S-transferase genes and susceptibility to colorectal cancer: a case-control study in an Indian population. PMID: 20688591 Ref: CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese. PMID: 21385088 Ref: Glutathione S-transferase (GST) gene polymorphisms, cigarette smoking and colorectal cancer risk among Chinese in Singapore. PMID: 21803734 Ref: Glutathione S-transferase mu gene variants and colorectal cancer development--use of sequence-specific probes for an Iranian population. PMID: 22126490 |
Ref: Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran. PMID: 22228187 Ref: Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy. PMID: 22234881 Ref: GSTM1 and GSTT1 polymorphisms and colorectal cancer risk in Chinese population: a meta-analysis. PMID: 22237425 Ref: N-Acetyltransferase 2 and glutathione s-transferase M1 in colon and rectal cancer cases from an industrialized area. PMID: 22686318 Ref: Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population. PMID: 22697302 Ref: Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients. PMID: 22909207 |
Ref: Microsomal epoxide hydrolase polymorphisms, cigarette smoking, and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study. PMID: 22415791 Ref: A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen. PMID: 22868256 Ref: Systematic review: diet-gene interactions and the risk of colorectal cancer. PMID: 23216531 Ref: Glutathione S-transferase M1-null genotype as risk factor for SOS in oxaliplatin-treated patients with metastatic colorectal cancer. PMID: 23287989 Ref: Pharmacogenetic analysis of adjuvant FOLFOX for Korean patients with colon cancer. PMID: 23314736 Ref: MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland. PMID: 23626689 Ref: Glutathione S-transferase T1 gene polymorphism and colorectal cancer risk: an updated analysis. PMID: 23773486 Ref: GST gene variants in synchronous colorectal cancers and synchronous association of colorectal cancers with other cancers. PMID: 23790786 Ref: Cytochrome P450 1A1, 2E1 and GSTM1 gene polymorphisms and susceptibility to colorectal cancer in the Saudi population. PMID: 23886179 Ref: Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy. PMID: 23894404 Ref: Cytotoxic and anti-inflammatory effects of onion peel extract on lipopolysaccharide stimulated human colon carcinoma cells. PMID: 24001438 Ref: Polymorphisms of GSTP1, ERCC2 and TS-3'UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients. PMID: 24137384 |
Ref: Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. PMID: 23946381 Ref: An updated meta-analysis of the association between GSTM1 polymorphism and colorectal cancer in Asians. PMID: 24014086 Ref: Glutathione S-transferase M1 polymorphism and colorectal cancer risk in Chinese population. PMID: 24197978 Ref: Cruciferous vegetables, glutathione S-transferase polymorphisms, and the risk of colorectal cancer among Chinese men. PMID: 24238877 Ref: Polymorphisms of glutathione-S-transferases M1, T1, P1 and susceptibility to colorectal cancer in a sample of the Tunisian population. PMID: 24254297 Ref: GSTM1-null genotype as a risk factor for sporadic colorectal cancer in a Romanian population. Association with the NAT2-rapid-acetylator phenotype and exposure to environmental factors. PMID: 24467372 Ref: Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently. PMID: 24714741 Ref: Genetic variants in the glutathione S-transferase genes and survival in colorectal cancer patients after chemotherapy and differences according to treatment with oxaliplatin. PMID: 24842074 Ref: Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option. PMID: 25167226 Ref: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients. PMID: 25370899 Ref: Association between glutathione S-transferase T1, M1, and P1 genotypes and the risk of colorectal cancer. PMID: 25408579 |
Ref: Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan. PMID: 25249451 Ref: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy. PMID: 25677447 Ref: Association between glutathione S-transferase M1 and T1 polymorphisms and colorectal cancer risk in patients from Kazakhstan. PMID: 25807650 Ref: GSTM1 polymorphism contribute to colorectal cancer in Asian populations: a prospective meta-analysis. PMID: 26219826 Ref: Epidemiological factors related to GSTM1 and GSTT1 genes deletion in colon and rectum cancers: A case-control study. PMID: 26406947 Ref: Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors. PMID: 26682223 |
Ref: Glutathione S-transferase M1 null genotype related to poor prognosis of colorectal cancer. PMID: 26831664 Ref: GSTM1 gene polymorphism and the risk of colorectal cancer in a Saudi Arabian population. PMID: 26909940 Ref: Can GSTM1 and GSTT1 polymorphisms predict clinical outcomes of chemotherapy in gastric and colorectal cancers? A result based on the previous reports. PMID: 27382306 Ref: Pharmacogenetic and ethnicity influence on oxaliplatin therapy for colorectal cancer: a meta-analysis. PMID: 27636246 Ref: Glutathione S-transferase T1, M1 and P1 Genetic Polymorphisms and Susceptibility to Colorectal Cancer in Turkey. PMID: 27644629 Ref: Role of GSTM1 Copy Number Variant in the Prognosis of Thai Colorectal Cancer Patients Treated with 5-FU-based Chemotherapy PMID: 27893202 Ref: Evaluation of deletion polymorphisms of glutathione S-transferase genes and colorectal cancer risk in ethnic Kashmiri population: A case-control study. PMID: 28485343 |
Ref: Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population. PMID: 28397463 |
Ref: The Interaction of Smoking with Gene Polymorphisms on Four Digestive Cancers: A Systematic Review and Meta-Analysis. PMID: 29721061 Ref: GSTM1, GSTT1, and GSTP1 polymorphisms and colorectal cancer risk in Polish nonsmokers. PMID: 29765533 Ref: The diagnostic potential of glutathione S-transferase (GST) polymorphisms in patients with colorectal cancer. PMID: 30106268 Ref: Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer. PMID: 30356976 |