Primary Site >> Colorectal Cancer

Gene >> GRPR

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Ref: Bombesin stimulates adhesion, spreading, lamellipodia formation, and proliferation in the human colon carcinoma Isreco1 cell line.
PMID: 10029091
Ref: Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans.
PMID: 10070042
Ref: High gastrin releasing peptide receptor mRNA level is related to tumour dedifferentiation and lymphatic vessel invasion in human colon cancer.
PMID: 10211100
Ref: The human gastrin-releasing peptide receptor gene structure, its tissue expression and promoter.
PMID: 11245983
Ref: Contribution of gastrin-releasing peptide and its receptor to villus development in the murine and human gastrointestinal tract.
PMID: 11960700
Ref: Human gastrin-releasing peptide receptor mediates sustained CREB phosphorylation and transactivation in HuTu 80 duodenal cancer cells.
PMID: 12220644
Ref: Increased frequency of gastrin-releasing peptide receptor gene mutations during colon-adenocarcinoma progression.
PMID: 12720295
Ref: Phosphorylation of focal adhesion kinase tyrosine 397 critically mediates gastrin-releasing peptide's morphogenic properties.
PMID: 14978737
Ref: Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor.
PMID: 15498503
Ref: (99m)Tc-(Hydrazinonicotinic acid-beta-Ala-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2)(tricine)(TPPTS)
PMID: 20641678
Ref: Consequence of gastrin-releasing peptide receptor activation in a human colon cancer cell line: a proteomic approach.
PMID: 16739997
Ref: Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase.
PMID: 16920698
Ref: Targeting the epidermal growth factor receptor in colorectal cancer: a potential therapeutic role for gastrin-releasing peptide receptor antagonists.
PMID: 18160806
Ref: GRP-induced up-regulation of Hsp72 promotes CD16+/94+ natural killer cell binding to colon cancer cells causing tumor cell cytolysis.
PMID: 18350254
Ref: Expression of GRP and its receptor is associated with improved survival in patients with colon cancer.
PMID: 19430935
Ref: Reduced NGF secretion by HT-29 human colon cancer cells treated with a GRPR antagonist.
PMID: 19519524
Ref: BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer.
PMID: 21474968
Ref: In vivo MR/optical imaging for gastrin releasing peptide receptor of prostate cancer tumor using Gd-TTDA-NP-BN-Cy5.5.
PMID: 20493715
Ref: Gastrin-releasing peptide signaling alters colon cancer invasiveness via heterochromatin protein 1Hsbeta.
PMID: 21281799
Ref: Identification of ChIP-seq mapped targets of HP1beta due to bombesin/GRP receptor activation.
PMID: 22704345
Ref: Bowel exposure in rectal cancer IMRT using prone, supine, or a belly board.
PMID: 21723637
Ref: Galpha13/PDZ-RhoGEF/RhoA signaling is essential for gastrin-releasing peptide receptor-mediated colon cancer cell migration.
PMID: 24958816
Ref: Investigation of bombesin peptide as a targeting ligand for the gastrin releasing peptide (GRP) receptor.
PMID: 27670095