Primary Site >> Stomach Cancer

Gene >> GRB2

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Ref: Gastrin and phorbol 12-myristate 13-acetate regulate the human histidine decarboxylase promoter through Raf-dependent activation of extracellular signal-regulated kinase-related signaling pathways in gastric cancer cells.
PMID: 9341140
Ref: Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition.
PMID: 11267961
Ref: Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.
PMID: 11809769
Ref: Targets of gene amplification and overexpression at 17q in gastric cancer.
PMID: 11980659
Ref: Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response.
PMID: 12719469
Ref: Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.
PMID: 14963045
Ref: Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation.
PMID: 15882975
Ref: FGF signaling network in the gastrointestinal tract (review).
PMID: 16773196
Ref: Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy.
PMID: 17211494
Ref: Increased expression of Gab2, a scaffolding adaptor of the tyrosine kinase signalling, in gastric carcinomas.
PMID: 17558859
Ref: Overexpression of Grb2/HER2 signaling in Chinese gastric cancer: their relationship with clinicopathological parameters and prognostic significance.
PMID: 19337752
Ref: Down-regulated miR-9 and miR-433 in human gastric carcinoma.
PMID: 19531230
Ref: Tyrosine phosphorylation of R3 subtype receptor-type protein tyrosine phosphatases and their complex formations with Grb2 or Fyn.
PMID: 20398064
Ref: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways.
PMID: 20651362
Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.
PMID: 20498032
Ref: Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells.
PMID: 22012247
Ref: Met receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodia.
PMID: 22366451
Ref: Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer.
PMID: 22383989
Ref: Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling.
PMID: 24469046
Ref: Intramolecular energies of the cytotoxic protein CagA of Helicobacter pylori as a possible descriptor of strains' pathogenicity level.
PMID: 29864542
Ref: MicroRNA-1258 suppresses tumour progression via GRB2/Ras/Erk pathway in non-small-cell lung cancer.
PMID: 30069987