Primary Site >> Colorectal Cancer

Gene >> GPX4

  • 2004
  • 2007
  • 2008
  • 2010
  • 2011
  • 2012
  • 2014
Ref: PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells.
PMID: 15274299
 Ref: Evidence that a polymorphism within the 3'UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer.
PMID: 18850177
 Ref: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.
PMID: 18483336
 Ref: Genetic variants in selenoprotein genes increase risk of colorectal cancer.
PMID: 20378690
 Ref: Dietary fish oil promotes colonic apoptosis and mitochondrial proton leak in oxidatively stressed mice.
PMID: 21490130
Ref: Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta-analysis.
PMID: 21765007
Ref: Expression of selenium-containing proteins in human colon carcinoma tissue.
PMID: 21868509
 Ref: Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells.
PMID: 22634395
 Ref: Selenium and cancer: a story that should not be forgotten-insights from genomics.
PMID: 24114479