Primary Site >> Colorectal Cancer
Gene >> GPLD1
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Ref: Biosynthesis of carcinoembryonic antigen (CEA) gene family members expressed in human tumor cell lines: evidence for cleavage of the glycosyl phosphatidyl inositol (GPI) anchor by GPI-PLC and GPI-PLD. PMID: 1815506 |
Ref: Increased activity and expression of phospholipase D2 in human colorectal cancer. PMID: 14552589 |
Ref: Evidence for CEA release from human colon cancer cells by an endogenous GPI-PLD enzyme. PMID: 15893415 Ref: Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation. PMID: 16824927 |
Ref: Expression of phospholipase D2 in human colorectal carcinoma. PMID: 17914593 |
Ref: Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells. PMID: 20711340 |
Ref: The C-terminal domain of PLD2 participates in degradation of protein kinase CKII beta subunit in human colorectal carcinoma cells. PMID: 21944249 |
Ref: Regulation of carcinoembryonic antigen release from colorectal cancer cells. PMID: 21725636 Ref: 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer. PMID: 22187071 |
Ref: Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells. PMID: 25475140 |
Ref: Extravirgin olive oil up-regulates CB(1) tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms. PMID: 25533906 |
Ref: Inhibition of phospholipaseD2 increases hypoxia-induced human colon cancer cell apoptosis through inactivating of the PI3K/AKT signaling pathway. PMID: 26614430 |
Ref: Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment. PMID: 30305726 |