Primary Site >> Colorectal Cancer
Gene >> GNAQ
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Ref: A 'metastasis-prone' signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. PMID: 20143136 Ref: A novel mechanism underlying phytate-mediated biological action-phytate hydrolysates induce intracellular calcium signaling by a Galphaq protein-coupled receptor and phospholipase C-dependent mechanism in colorectal cancer cells. PMID: 20146267 |
Ref: Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer. PMID: 23434733 Ref: Identification of novel point mutations in splicing sites integrating whole-exome and RNA-seq data in myeloproliferative diseases. PMID: 24498620 |
Ref: Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing. PMID: 27568332 Ref: Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing. PMID: 27756406 |
Ref: Whole-exome sequencing identified mutational profiles of high-grade colon adenomas. PMID: 28179590 |