Primary Site >> Colorectal Cancer
Gene >> GLS
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Ref: Significance of Lgr5(+ve) cancer stem cells in the colon and rectum. PMID: 21125339 |
Ref: [KRAS and BRAF gene mutations in correlation with clinicopathologic features of colorectal carcinoma in Chinese]. PMID: 23157824 |
Ref: Expression of glutaminase is upregulated in colorectal cancer and of clinical significance. PMID: 24696726 |
Ref: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. PMID: 26317652 |
Ref: Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells. PMID: 27902968 Ref: Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells. PMID: 28498807 Ref: Low-Dose Paclitaxel Inhibits Tumor Cell Growth by Regulating Glutaminolysis in Colorectal Carcinoma Cells. PMID: 28522974 Ref: Glutaminase sustains cell survival via the regulation of glycolysis and glutaminolysis in colorectal cancer. PMID: 28928849 |
Ref: Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis. PMID: 29730197 Ref: Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells. PMID: 30103008 |