Primary Site >> Colorectal Cancer
Gene >> GLI3
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Ref: Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells. PMID: 15072830 |
Ref: Identification and characterization of rat Desert hedgehog and Indian hedgehog genes in silico. PMID: 15645142 Ref: Comparative genomics on Sonic hedgehog orthologs. PMID: 16142377 |
Ref: Sonic hedgehog-Gli1 pathway in colorectal adenocarcinomas. PMID: 17461467 Ref: Hedgehog signaling pathway is inactive in colorectal cancer cell lines. PMID: 17683069 |
Ref: Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation. PMID: 19280222 |
Ref: Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. PMID: 20610541 |
Ref: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. PMID: 21747117 |
Ref: Abrogation of Gli3 expression suppresses the growth of colon cancer cells via activation of p53. PMID: 22227409 |
Ref: Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes. PMID: 23176625 |
Ref: GSK3beta and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3beta downregulates the signaling pathway and reduces cell proliferation. PMID: 26385428 |
Ref: Clonal Structures of Regionally Synchronous Gastric Adenomas and Carcinomas. PMID: 29945994 |